TCTAP A-020 Gender Difference in Short Term Mortality After Acute Myocardial Infarction in Korea

Acute myocardial infarction (AMI) is a leading cause of death and not a few of these patients are combined with acidemia. This study aimed to detect the association of acidemia with short-term mortality of AMI patients. A total of 972 AMI patients were selected from the Medical Information Mart for Intensive Care (MIMIC) III database for analysis. Propensity-score matching (PSM) was used to reduce the imbalance. Kaplan-Meier survival analysis was used to compare the mortality, and Cox-proportional hazards model was used to detect related factors associated with mortality. After PSM, a total of 345 non-acidemia patients and 345 matched acidemia patients were included. The non-acidemia patients had a significantly lower 30-day mortality (20.0% vs. 28.7%) and lower 90-day mortality (24.9% vs. 31.9%) than the acidemia patients ( P < 0.001 for all). The severe-acidemia patients (PH < 7.25) had the highest 30-day mortality (52.6%) and 90-day mortality (53.9%) than non-acidemia patients and mild-acidemia (7.25 ≤ PH < 7.35) patients ( P < 0.001). In Cox-proportional hazards model, acidemia was associated with improved 30-day mortality (HR = 1.518; 95%CI = 1.110-2.076, P = 0.009) and 90-day mortality (HR = 1.378; 95%CI = 1.034 -1.837, P = 0.029). These results suggest that severe acidemia is associated with improved 30-day mortality and 90-day mortality of AMI patients.

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59 Admission hyperglycemia is an independent predictor of acute heart failure and short-term mortality in patients after acute myocardial infarction in the contemporary primary angioplasty era

European Journal of Heart Failure Supplements ◽

10.1016/s1567-4215(05)80024-4 ◽

2005 ◽

Vol 4 (1) ◽

pp. 10-10

Keyword(s):

Myocardial Infarction ◽

Heart Failure ◽

Acute Myocardial Infarction ◽

Acute Heart Failure ◽

Independent Predictor ◽

Primary Angioplasty ◽

Short Term ◽

Short Term Mortality

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Abstract P155: Low Socioeconomic Status Relates to Short-term Mortality Risk After Acute Myocardial Infarction, Especially in Men: Results From a Nationwide Study

Circulation ◽

10.1161/circ.125.suppl_10.ap155 ◽

2012 ◽

Vol 125 (suppl_10) ◽

Author(s):

Louise van Oeffelen ◽

Charles Agyemang ◽

Carla Koopman ◽

Michiel Bots ◽

Karien Stronks ◽

...

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Low Socioeconomic Status ◽

Case Fatality ◽

Day Case ◽

Short Term ◽

Low Socioeconomic ◽

Nationwide Study ◽

Short Term Mortality ◽

Age And Sex

Introduction Previous studies show poorer short-term prognosis after an acute myocardial infarction (AMI) in subjects with a low socioeconomic status (SES). Yet, the magnitude of these relations may differ by age and sex. Data on these issues are however scarce. Methods A nationwide Dutch cohort of first AMI patients between January 1 st 1998 and December 31 st 2007 was identified through linkage of national registers. SES was defined as the standardized disposable income on household level in 1997. For every SES quintile, age- and sex- specific short-term mortality rates were quantified. Logistic regression models were used to estimate differences between SES quintiles in out-of-hospital mortality and 28-day case-fatality. Results We identified 70.368 first AMI patients with income data available, of which 55.860 were men and 14.508 were women. There were strong inverse associations between SES and both short-term mortality outcomes when comparing the lowest with the highest income quintile (out-of-hospital mortality: Odds Ratio (OR) 1.26; 95% Confidence Interval (95% CI) 1.18–1.34), 28-day case-fatality: OR 1.26; 95% CI 1.15–1.37). For men graded relations were found across quintiles of SES, whereas for women only differences between the lowest and the highest quintile were seen. These relations remained consistent across all age categories, except for women below 55 years of age. Conclusion The results from our nationwide study show an increased risk of short-term mortality after a first AMI in subjects with a low SES of all ages, which is most pronounced in men.

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