scholarly journals TCT-339 Partial Inferior Vena Cava Occlusion During Exercise in Heart Failure Patients Prevents Left Ventricular Pressure Overload, Improves Exercise Times, and Reduces Respiratory Rate: Mechanical “Balancing” of Biventricular Function as a Novel Therapy for Heart Failure Qualify of Life

2019 ◽  
Vol 74 (13) ◽  
pp. B336
Author(s):  
Daniel Kaiser ◽  
Clayton Kaiser ◽  
James Canfield ◽  
Rupal Patel ◽  
Frederick St. Goar
1980 ◽  
Vol 238 (4) ◽  
pp. H423-H429 ◽  
Author(s):  
O. Stokland ◽  
M. M. Miller ◽  
A. Ilebekk ◽  
F. Kiil

To examine left ventricular responses to aortic occlusion, changes in end-diastolic volume (EDV) and end-systolic volume (ESV) were estimated by ultrasonic recordings of myocardial distances in atropinized open-chest dogs. During aortic occlusion EDV and ESV increased equally, systolic left ventricular pressure (LVP) rose by 86 +/- 8 mmHg, and blood flow more than doubled in the superior vena cava and fell by 90% in the inferior vena cava. During combined occlusion of aorta and inferior vena cava, systolic LVP and superior vena cava flow did not rise above control and EDV declined. By infusing 25 +/- 2 ml/kg body wt of blood during combined occlusion, the effects of aortic occlusion could be reproduced; control values before blood infusion were reestablished by withdrawal of only one-third of the infused volume, indicating a shunt line along the spinal column. Thus during aortic occlusion, transfer of blood accounts for the rise in EDV and increased activation of the Frank-Starling mechanism; increased afterload raises ESV as much as EDV in anesthetized dogs not subjected to sympathetic stimulation. Consequently, stroke volume is maintained and systolic LVP increased.


1996 ◽  
Vol 60 (9) ◽  
pp. 652-661 ◽  
Author(s):  
Koshi Miyahara ◽  
Atsushi Mikuniya ◽  
Hiroyuki Hanada ◽  
Takemichi Kanazaw ◽  
Kogo Onodera ◽  
...  

Cardiology ◽  
2021 ◽  
pp. 1-8
Author(s):  
Yuanming Yan ◽  
Mingfang Ye ◽  
Xianfeng Dong ◽  
Qin Chen ◽  
Huashan Hong ◽  
...  

<b><i>Introduction:</i></b> Contrast-induced nephropathy (CIN) is a common complication resulting from the administration of contrast media. This study was designed to determine whether inferior vena cava (IVC) ultrasonography (IVCU)-guided hydration can reduce the risk of CIN in chronic heart failure patients undergoing coronary angiography or coronary angiography with percutaneous coronary intervention compared with standard hydration. <b><i>Methods:</i></b> This prospective clinical trial enrolled 207 chronic heart failure patients from February 2016 to November 2017, who were randomly assigned to either the IVCU-guided hydration group (<i>n</i> = 104) or the routine hydration group (<i>n</i> = 103). In the IVCU-guided group, the hydration infusion rate was set according to the IVC diameter determined by IVCU, while the control group received intravenous infusion of 0.9% saline at 0.5 mL/(kg·h). Serum Cr was measured before and 48–72 h after the procedure. All patients were followed up for 18 months. The incidence of nephropathy and major adverse cardiovascular or cerebrovascular events (MACCEs) was also compared between the 2 groups. <b><i>Results:</i></b> Statistically significant difference between the 2 groups regarding the occurrence of CIN was observed (12.5 vs. 29.1%, <i>p</i> = 0.004). The hydration volume of the IVCU-guided group was significantly higher than that of the routine group (<i>p</i> &#x3c; 0.001). In addition, patients receiving IVCU-guided hydration had significantly lower risk of developing MACCEs than patients in the control group during the 18-month follow-up (14.4 vs. 27.2%, <i>p</i> = 0.027). <b><i>Conclusion:</i></b> Our findings support that IVCU-guided hydration is superior to standard hydration in prevention of CIN and may substantially reduce longtime composite major adverse events.


Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Yuanming Yan ◽  
Mingfang Ye ◽  
qin chen ◽  
yukun luo

Introduction: Contrast-induced nephropathy (CIN) is a common complication resulting from the administration of contrast media. This study was designed to determine whether inferior vena cava ultrasonography (IVCU)-guided hydration can reduce the risk of CIN in chronic heart failure patients undergoing coronary angiography or coronary angiography with percutaneous coronary intervention (PCI) than standard hydration. Methods: This prospective clinical trial enrolled 207 chronic heart failure patients from February 2016 to November 2017, who were randomly assigned to either IVCU-guided hydration group (n = 104) or the routine hydration group (n = 103). In the IVCU-guided group, the hydration infusion rate was set according to inferior vena cava diameter (IVC-D) determined by IVCU; while the control group received intravenous infusion of 0.9% saline at 0.5 ml/((kg·h)). Serum creatinine (SCr) was measured before and 48-72 hours after procedure. All patients were followed up for 18 months. The incidence of nephropathy and major adverse cardiovascular or cerebrovascular events (MACCE) were also compared between two groups. Results: Statistically significant difference between two groups regarding the occurrence of CIN were observed (12.5% vs. 29.1%, p = 0.003); The hydration volume of the IVCU-guided group is significantly higher than routine group (p<0.001). In addition, patients receiving IVCU-guided hydration had significantly lower risk of developing MACCE compared with patients in control group during 18 months follow-up (14.4% vs. 27.2%, p = 0.027). Conclusions: IVCU-guided hydration is superior to standard hydration in prevention of CIN and substantially reduce longtime composite major adverse events.


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