Association between domestic water hardness, chlorine, and atopic dermatitis risk in early life: A population-based cross-sectional study

Abstract Background Previous studies have revealed that current secondhand smoke exposure showed highly suggestive evidence for increased risk of simultaneous sleep problems in children. Data on the associations between early-life exposure to SHS with subsequent sleep problems in children were scarce. We aimed to evaluate the associations of early-life SHS exposure with sleep problems in children. Methods In this cross-sectional study, children were recruited from elementary and middle schools in Liaoning Province, China between April 2012 and January 2013. We assessed early-life SHS exposure (pregnancy and the first 2 years of life) via questionnaires. Sleep problems and different types of sleep-related symptoms were measured based on the validated tool of the Sleep Disturbance Scale for Children (SDSC). Generalized linear mixed models were applied to estimate the associations of early-life SHS exposure with sleep problems. Results We included a total of 45,562 children (22,657 [49.7%] males; mean [SD] age, 11.0 [2.6] years) and 6167 of them (13.5%) were exposed to early-life SHS during both pregnancy and the first 2 years of life. Compared with unexposed counterparts, children exposed to early-life SHS had higher total T-scores of SDSC (β = 4.32; 95%CI: 4.06, 4.58) and higher odds of increased sleep problems (OR = 2.14; 95%CI: 1.89, 2.42). When considering different sleep-related symptoms, the associations between early-life SHS exposure and symptom of sleep-wake transition disorders (i.e., bruxism) were the strongest in all analyses. Conclusions Early-life SHS exposure was associated with higher odds of global sleep problems and different sleep-related symptoms in children aged 6–18 years. Our findings highlight the importance to strengthen efforts to support the critical importance of maintaining a smoke-free environment especially in early life.

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25442 Relationship between topical corticosteroid utilization and atopic dermatitis severity and burden: A population-based cross-sectional study

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2021.06.258 ◽

2021 ◽

Vol 85 (3) ◽

pp. AB58

Author(s):

Alexander Egeberg ◽

Jeanette Halskou Hougaard ◽

Linda Weyler ◽

Philip Sugerman ◽

Jacob P. Thyssen

Keyword(s):

Atopic Dermatitis ◽

Topical Corticosteroid ◽

Population Based ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Atopic Dermatitis Severity

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Adult Atopic Dermatitis with Comorbid Atopic Disease is Associated with Increased Risk of Infections: A Population-Based Cross-Sectional Study

Dermatology and Therapy ◽

10.1007/s13555-017-0172-7 ◽

2017 ◽

Vol 7 (1) ◽

pp. 111-121 ◽

Cited By ~ 5

Author(s):

Saisindhu Narala ◽

Tissa R. Hata

Keyword(s):

Atopic Dermatitis ◽

Atopic Disease ◽

Population Based ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Increased Risk

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Faculty Opinions recommendation of Body composition and basal metabolic rate in Hidradenitis Suppurativa: a Danish population-based and hospital-based cross-sectional study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726010578.793534526 ◽

2017 ◽

Author(s):

Iltefat Hamzavi

Keyword(s):

Body Composition ◽

Metabolic Rate ◽

Basal Metabolic Rate ◽

Hidradenitis Suppurativa ◽

Population Based ◽

Cross Sectional Study ◽

Sectional Study ◽

Danish Population ◽

Cross Sectional

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Cow’s milk exposure and atopic dermatitis after six months of age

Paediatrica Indonesiana ◽

10.14238/pi56.6.2016.325-9 ◽

2017 ◽

Vol 56 (6) ◽

pp. 325

Author(s):

Surya Jayanti Kadek ◽

Dewi Kumara Wati Ketut ◽

Karyana Putu Gede

Keyword(s):

Atopic Dermatitis ◽

Maternal Diet ◽

Multiple Logistic Regression Analysis ◽

Cross Sectional Study ◽

Cow’S Milk ◽

Milk Formula ◽

Sectional Study ◽

Cross Sectional ◽

Cow's Milk ◽

Study Population

Background About 60% of individuals with atopic dermatitis (AD) develop their first manifestation during infancy. Cow’s milk (CM) exposure is considered to be a risk factor for AD.Objective To evaluate for an association between cow’s milk exposure and atopic dermatitis in infants > 6 months of age. Methods This cross-sectional study consisted of subjects from a previous study and new subjects recruited in order to meet the minimum required number of subjects. Our study population comprised 120 infants, born between 1 February and 30 November, 2012 in Sanglah Hospital, Denpasar. Subjects were divided into CM and non-CM groups and analyzed for their risk of AD. Subjects were included to CM group if they were fed with cow’s milk/formula and included to non-CM group if they were breastfeed exclusively in the first six months of life. Other possible risk factors were assessed by multivariate analysis. Results One hundred twenty subjects were enrolled and analyzed (59 in the CM and 61 in the non-CM groups). The prevalence of AD was 30%. Multiple logistic regression analysis revealed a significant association between CM exposure and AD, with odds ratio (OR) 2.37 (95%CI 1.036 to 5.420; P=0.04). In addition, maternal diet including eggs and/or cow’s milk during the breastfeeding period was significantly associated with AD in infants (OR 3.18; 95%CI 1.073 to 9.427; P=0.04).Conclusion Cow’s milk exposure is significantly associated with atopic dermatitis in infants > six months of age.

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