Screening With Serology Testing Children With Asthma Could Contribute To Substantial Cost Savings To US Payors: A Population-Based Simulation Study

Recent years have seen the approvals, more so in the EU than the United States, of follow-on biological drugs. These products have been new formulations of recombinant therapeutic proteins, developed to compete with the marketed originator products. Intended to closely mimic the originator products in terms of chemistry and therapeutic properties, these so-called ‘biosimilar’ products were initially conceived to be developed according to abbreviated development programmes, presumably at a substantial cost savings to both the drug developer and the consumer. With several such products now recently approved, however, it has become clear that their development programmes have been quite extensive and not particularly abbreviated. Accordingly, cost savings to consumers appear to be relatively modest.

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The factors behind working in virtual community

Journal of Global Operations and Strategic Sourcing ◽

10.1108/jgoss-03-2018-0011 ◽

2019 ◽

Vol 12 (2) ◽

pp. 246-267 ◽

Cited By ~ 1

Author(s):

Anitha Acharya

Keyword(s):

Virtual Teams ◽

Virtual Community ◽

Cost Savings ◽

Working Hours ◽

Substantial Cost ◽

Content Type ◽

Part Time ◽

Research Findings ◽

Hourly Basis ◽

Practical Implications

Purpose In this paper, the prior research on virtual teams was reviewed to assess the state of the literature. The purpose of this paper is to determine why individuals prefer working in virtual teams (also termed liquid workers and part-time workers). Previous researchers have focussed on the benefits that organizations receive if they hire liquid workers, but to date, no research has been conducted to determine the perspective of these liquid workers. The various definitions of virtual teams are discussed and an integrative definition is proposed that suggests all teams may be defined in terms of their extent of virtualness. Design/methodology approach A systematic review of the literature on virtual teams was conducted. The data were collected from 12 informants. A thematic analysis was used to analyse the data. Findings Six main themes were identified, namely, pliability, opportunities, increased earnings, vigour, family and transportation. Research limitations/implications This study was conducted in a three-metropolitan city in India and warrants being extended to rural and international settings to gain additional insights and confirmation of the research findings. Practical implications It is suggested that organizations who recruit liquid workers will be in a position for substantial cost savings; this is because organizations usually make payment of liquid workers’ wages on an hourly basis. This will help the organizations to schedule the number of working hours depending on their needs. Originality/value The current study is novel as there is a paucity of research in identifying the factors behind working in the virtual community in India. This study presents the first research of its kind to the best knowledge of the author, and the findings will be valuable for companies who are looking for cost savings.

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Documenting the Benefits and Cost Savings of a Large Multistate Cancer Pathway Program From a Payer's Perspective

Journal of Oncology Practice ◽

10.1200/jop.2012.000871 ◽

2013 ◽

Vol 9 (5) ◽

pp. e241-e247 ◽

Cited By ~ 30

Author(s):

Eugene D. Kreys ◽

Jim M. Koeller

Keyword(s):

Clinical Pathways ◽

Cost Savings ◽

Substantial Cost ◽

Physician Compliance

Broadly implemented clinical pathways can achieve reasonable physician compliance, resulting in substantial cost savings.

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Asthma and subsequent school performance at age 15–16 years: A Swedish population-based sibling control study

Scientific Reports ◽

10.1038/s41598-020-64633-w ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Cecilia Lundholm ◽

Bronwyn K. Brew ◽

Brian M. D’Onofrio ◽

Emma Caffrey Osvald ◽

Henrik Larsson ◽

...

Keyword(s):

School Performance ◽

Population Based ◽

Uncontrolled Asthma ◽

Swedish Population ◽

Grade Point ◽

Familial Factors ◽

Cohen’S D ◽

Children With Asthma ◽

Cohen's D ◽

And Control

AbstractAsthma may negatively affect children’s school performance, such as grades and exam results. Results from previous studies have shown varying results and may have suffered from confounding and other biases. We used a Swedish population-based cohort of 570,595 children with data on asthma (including severity and control) in Grades 7–8 and 9, school performance from Grade 9 (grade point sum, non-eligibility for upper secondary school and national test results) and measured confounders from national registers. We used sibling comparisons to account for unmeasured familial factors. Children with asthma and severe asthma performed slightly better in school than children without asthma when adjusting for measured confounders, but the associations were attenuated in sibling comparisons. In contrast, children with uncontrolled asthma performed slightly worse (e.g. Grade 9: βadj = −9.9; 95% CI −12.8 to −7.0; Cohen’s d = 0.16). This association remained for uncontrolled asthma in Grade 9 in sibling comparisons (Grade 9: β = −7.7 points; 95% CI −12.6 to −2.6; Cohen’s d = 0.12), but not for Grades 7–8. The attenuation of estimates when controlling for familial factors using sibling comparisons suggests that the differences were due to familial factors, rather than being causal. The remaining associations in sibling comparisons between uncontrolled asthma in Grade 9 and school performance are consistent with a causal association.

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POPULATION-BASED AND OPPORTUNISTIC SCREENING AND ERADICATION OF HELICOBACTER PYLORI

International Journal of Technology Assessment in Health Care ◽

10.1017/s0266462399015445 ◽

1999 ◽

Vol 15 (4) ◽

pp. 649-660 ◽

Cited By ~ 3

Author(s):

James M. Mason ◽

Paul Moayyedi ◽

Philip J. Young ◽

Sara Duffett ◽

Will Crocombe ◽

...

Keyword(s):

Helicobacter Pylori ◽

Cost Savings ◽

Population Based ◽

Opportunistic Screening ◽

Test Results ◽

Data Set ◽

Limited Dependent Variable ◽

H Pylori ◽

The Cost ◽

Care Costs

Objectives: To examine whether screening and eradication of Helicobacter pylori by population-based invitation or opportunistic screening by general practitioners reduces costs to the National Health Service (NHS) of treating dyspepsia.Methods: A limited dependent, variable, two-step regression analysis was used to explore the baseline annual health care costs of dyspepsia for men and women aged 40–49 enrolled in the Leeds H. pylori screening and eradication trial.Results: Epidemiological and clinical questionnaires, general practitioner notes, and 13C urea breath test results were available for 4,754 individuals. After adjusting for covariates, H. pylori was associated with a 6.7% increased probability of incurring gastrointestinal-related NHS costs (p < .0001) in the population aged 40-49. Additionally, H pylori increased average costs in those who seek medical care (p = .001). In consequence, H. pylori is associated with an average increased cost to the NHS of £0.30 per year (95% CI: £0.17 to £0.45) per adult aged 40–49. In those consulting for dyspepsia, the increased cost to the NHS was £1.04 per year (95% CI: £0.42 to £1.75) per patient. The cost of population screening and treatment would not be recovered in reduced dyspepsia costs in the lifetime of those screened. Assuming laboratory-based serology screening is used opportunistically in patients presenting with dyspepsia, it is estimated that costs would be recouped in 18 years.Conclusions: This observational data set suggests that the costs of screening and treatment in all individuals aged 40–49 or in those presenting in primary care with dyspeptic symptoms are unlikely to be attractive on the basis of cost savings alone.

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