The Association Between Family History of Atopy and Food Allergy in Hispanic Children

2021 ◽  
Vol 147 (2) ◽  
pp. AB116
Author(s):  
Stephania Lairet ◽  
Stanislav Ivanov ◽  
Jose Calderon ◽  
Vivian Hernandez-Trujillo
2019 ◽  
Vol 143 (2) ◽  
pp. AB83
Author(s):  
Justin M. Zaslavsky ◽  
Waheeda Samady ◽  
Jialing Jiang ◽  
Christopher M. Warren ◽  
Bridget M. Smith ◽  
...  

2008 ◽  
Vol 25 (9) ◽  
pp. 1043-1048 ◽  
Author(s):  
C. Koebnick ◽  
L. A. Kelly ◽  
C. J. Lane ◽  
C. K. Roberts ◽  
G. Q. Shaibi ◽  
...  

2013 ◽  
Vol 10 (11) ◽  
pp. 5364-5377 ◽  
Author(s):  
Jennifer Koplin ◽  
Katrina Allen ◽  
Lyle Gurrin ◽  
Rachel Peters ◽  
Adrian Lowe ◽  
...  

BMJ Open ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. e024594 ◽  
Author(s):  
Adrian Lowe ◽  
John Su ◽  
Mimi Tang ◽  
Caroline J Lodge ◽  
Melanie Matheson ◽  
...  

IntroductionThe skin is an important barrier against environmental allergens, but infants have relatively impaired skin barrier function. There is evidence that impaired skin barrier function increases the risk of allergic sensitisation, atopic dermatitis (AD) and food allergy. We hypothesise that regular prophylactic use of emollients, particularly those that are designed to improve skin barrier structure and function, will help prevent these conditions. With the aim of determining if application of a ceramide-dominant emollient two times per day reduces the risk of AD and food allergy, we have commenced a multicentre phase III, outcome assessor blinded, randomised controlled trial of this emollient applied from birth to 6 months.Methods and analysisInfants (n=760) with a family history of allergic disease will be recruited from maternity hospitals in Melbourne. The primary outcomes are as follows: the presence of AD, assessed using the UK Working Party criteria, and food allergy using food challenge, in the first 12 months of life as assessed by a blinded study outcome assessor. Secondary outcomes are as follows: food sensitisation (skin prick test), skin barrier function, AD severity, the presence of new onset AD after treatment cessation (between 6 and 12 months) and the presence of parent reported AD/eczema. Recruitment commenced in March 2018.Ethics and disseminationThe PEBBLES Study is approved by the Human Research Ethics Committees of the Royal Children’s Hospital (RCH) (#37090A) and the Mercy Hospital for Women (2018–008). Parents or guardians will provide written informed consent. Outcomes will be disseminated through peer-reviewed publications and presented at scientific conferences.Trial registration numbersACTRN12617001380381 andNCT03667651.


2011 ◽  
Vol 8 (3) ◽  
pp. 41-47
Author(s):  
Svetlana Nikolaevna Denisova ◽  
M Yu Belitskaya ◽  
T B Sentsova ◽  
I Ya Kon' ◽  
O O Kirillova ◽  
...  

Aim. to analyze a family history of the allergic diseases, course of pregnancy and delivery in mothers, effect of concomitant diseases on the development and course of food allergy in infants. methods. We examined 471 infants with food allergy and different severity index of the atopic dermatitis (AD). Moderate and severe AD were more common at the age of 0-12 months old than at the age of 12-36 months old (80,9 and 55,6%, respectively). in boys of the 12-36 months severe course of the disease was more common then in girls at the same age (14,6 and 7,3%, respectively). We used SCORAD index for estimation of severity of AD. Results. positive family histories of the allergic diseases were revealed in 67,9 and 67,3% of the infants with moderate and severe course of AD, respectively. in the half of these infants allergic diseases were found in the maternal line. Disturbances of the pregnancy and delivery in mothers of the infants with and without AD were equal; however these disturbances were more common in mothers of the infants with severe AD. the postnatal risk factors of allergy were revealed in 11,7% of infants: prematurity (3,2%), prenatal hypotrophy (4,7%), intranatal asphyxia (2,3%), cephalohaematoma (1,5%). Conclusion. the positive family history of allergy was high in all infants with AD independently on the age of the appearance of first signs of food allergy. Mothers with pathological course of pregnancy and delivery more often had an infants with severe course of AD. prevalence of the postnatal risk factors in healthy and ill infants was equal.


2014 ◽  
Vol 10 (S2) ◽  
Author(s):  
Arunmozhi Dominic ◽  
Vaishaali Manga ◽  
Immaculate Nevis ◽  
Laura Kim ◽  
Harold Kim

1982 ◽  
Vol 25 (4) ◽  
pp. 482-486 ◽  
Author(s):  
Robin A. Seider ◽  
Keith L. Gladstien ◽  
Kenneth K. Kidd

Time of language onset and frequencies of speech and language problems were examined in stutterers and their nonstuttering siblings. These families were grouped according to six characteristics of the index stutterer: sex, recovery or persistence of stuttering, and positive or negative family history of stuttering. Stutterers and their nonstuttering same-sex siblings were found to be distributed identically in early, average, and late categories of language onset. Comparisons of six subgroups of stutterers and their respective nonstuttering siblings showed no significant differences in the number of their reported articulation problems. Stutterers who were reported to be late talkers did not differ from their nonstuttering siblings in the frequency of their articulation problems, but these two groups had significantly higher frequencies of articulation problems than did stutterers who were early or average talkers and their siblings.


2001 ◽  
Vol 120 (5) ◽  
pp. A442-A442
Author(s):  
P TSIBOURIS ◽  
M HENDRICKSE ◽  
P ISAACS

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