Mental health outcome of long-term and episodic adolescent depression: 15-year follow-up of a community sample

2011 ◽  
Vol 130 (3) ◽  
pp. 395-404 ◽  
Author(s):  
U. Jonsson ◽  
H. Bohman ◽  
L. von Knorring ◽  
G. Olsson ◽  
A. Paaren ◽  
...  
Keyword(s):  
Mental Health ◽  
Health Outcome ◽  
Adolescent Depression ◽  
Community Sample ◽  
Mental Health Outcome

Long-term mental health outcome of returning migrant children and adolescents

1998 ◽  
Vol 7 (4) ◽  
pp. 219-224 ◽  
Author(s):  
L. Vuorenkoski ◽  
I. Moilanen ◽  
A. Myhrman ◽  
O. Kuure ◽  
V. Penninkilampi ◽  
...  
Keyword(s):  
Mental Health ◽  
Health Outcome ◽  
Children And Adolescents ◽  
Migrant Children ◽  
Mental Health Outcome

scholarly journals The long-term mental health outcome of adolescent with depression and alcohol abuse comorbidity

2021 ◽  
Vol 31 (Supplement_3) ◽  
Author(s):  
S Brolin Låftman ◽  
R Ssegonja ◽  
I Alaie ◽  
U Jonsson ◽  
H Bohman
Keyword(s):  
Mental Health ◽  
Alcohol Abuse ◽  
Adolescent Depression ◽  
Diagnostic Interview ◽  
Health Consequences ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Structured Diagnostic Interview

Abstract Background Alcohol abuse often co-occurs with adolescent depression and about 1-2% suffer from the dual diagnosis in adolescence. This group is often undertreated or receive inadequate treatment for either of the conditions. Both conditions affect the developing brain and poor long-term outcome might be a potential risk. Yet, long-term follow-up studies are scarce. The aim of this study was to analyse if adolescent depression and alcohol abuse predict poorer mental health in adulthood compared to individuals without either or both conditions. Methods A community-based sample of individuals with adolescent depression in 1991-93 and matched non-depressed peers were followed up using a structured diagnostic interview after 15 years. The participation rate was 65% (depressed n = 227; non-depressed controls n = 155). Information on alcohol abuse in adolescence was collected at baseline with a structured interview. The outcome was mental disorders between the ages 19-31 years; information on depression and alcohol abuse was collected at the follow-up with a structured diagnostic interview. The statistical method used was binary logistic regression. Results Adolescents with depression and alcohol abuse had an excess risk of recurrence of depression (OR 2.12, p < 0.05) and alcohol abuse (OR 6.72, p < 0.01) in adulthood, compared with adolescents with depression only, even when adjusted for confounders. Adolescents with alcohol abuse only had not significantly worse long-term outcome compared with their healthy peers. Conclusions The co-occurrence of depression and alcohol abuse in adolescence is associated with long-lasting health consequences compared to either condition alone. This finding indicates that there is a need to prioritize this group of patients that is at risk of suboptimal treatment, and to further develop effective treatment adjusted to the co-occurring condition. Key messages The co-occurrence of adolescent depression and alcohol abuse has long lasting mental health consequences compared to either condition alone. Improved treatment methods are important for this group of adolescents.

Six-month and 12-month mental health outcome of medical and surgical patients admitted to general hospital

2000 ◽  
Vol 30 (2) ◽  
pp. 359-367 ◽  
Author(s):  
M. BALESTRIERI ◽  
G. BISOFFI ◽  
M. DE FRANCESCO ◽  
B. ERIDANI ◽  
M. MARTUCCI ◽  
...  
Keyword(s):  
Mental Health ◽  
Health Outcome ◽  
General Hospital ◽  
Psychiatric Morbidity ◽  
Structured Interview ◽  
Poor Mental Health ◽  
Mental Health Outcome ◽  
Second Phase ◽  
Hospital Patients

Background. We have recently reported a two-phase study on psychiatric morbidity in a sample of general hospital patients. This paper reports the results of the 6-month and 12-month follow-up of these patients.Methods. The screening questionnaire was the GHQ-12. The main diagnostic instrument used in the second phase was the CIDI-PHC. All patients who had been interviewed with CIDI-PHC (N = 363) were followed-up and the baseline assessment was compared with the scoring on questionnaires administered in the 6-month postal enquiry and with the psychopathological status at 12-month, elicited with a telephone structured interview.Results. Sixty-two and 87% of patients completed the 6- and 12-month follow-up assessment respectively. The first follow-up indicated no significant decrease in the level of symptoms. The 12-month follow-up interview showed that 23% of males and 40% of females had poor/mostly poor mental health. The logistic model showed that females with a definite ICD-10 diagnosis, admitted to a medical department, who had consumed psychotropic drugs in the previous year, had the most unfavourable outcome. The risk of a poor/mostly poor outcome steadily increased with the severity of the psychopathology during hospitalization.Conclusion. In medical and surgical general hospital patients the risk factors associated with a poor mental health outcome are similar to those found in primary care patients. Greater attention should be paid in assessing routinely mental health status of general hospital patients during hospitalization.

Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis
Keyword(s):  
Mental Health ◽  
Mental Disease ◽  
Brain Disorders ◽  
Social Stressors ◽  
Labor Education ◽  
Mental Diseases ◽  
Long Term Follow Up ◽  
Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

scholarly journals 332 - Electroconvulsive therapy in older adults with major depression was not associated with cognitive decline during a 15-year follow-up

2020 ◽  
Vol 32 (S1) ◽  
pp. 91-91
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Major Depression ◽  
Cognitive Decline ◽  
Electroconvulsive Therapy ◽  
Antidepressant Treatment ◽  
Community Sample ◽  
Control Group

AUTHORS:Kerstin Johansson, Karolina Thömkvist, Ingmar Skoog and Sacuiu SF* (*presenter)OBJECTIVE:To determine the effects of electroconvulsive therapy (ECT) in major depression in relation to the development of dementia during long-term follow-up.METHOD:In an observational clinical prospective study of consecutive patients 70 years and older diagnosed with major depression at baseline 2000-2004 (n=1090), who were free of dementia and received antidepressant treatment, with or without ECT, we sought to determine if cognitive decline (mild cognitive impairment and dementia) during 15 -year follow-up was associated with receiving ECT at baseline. The control group was selected among the participants in the Gothenburg H70 Birth Cohort Studies matched by age group and sex 1:1.RESULTS:Among patients with affective syndromes 7% received ECT. During follow-up, 157 patients were diagnosed with dementia, equal proportions among those who received ECT (14.5%) and those who did not receive ECT (14.5%). The relation between ECT and cognitive decline remained non-significant irrespective antidepressive medication or presence of mild cognitive impairment at baseline.CONCLUSION:Preliminary results indicate that ECT was not associated with the development of cognitive decline in the long-term in a hospital-based cohort of 70+ year-olds. The results remain to verify against controls from a representative community sample.

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