Early life stress, resilience and emotional dysregulation in major depressive disorder with comorbid borderline personality disorder

2018 ◽  
Vol 236 ◽  
pp. 113-119 ◽  
Author(s):  
Min-Kyeong Kim ◽  
Jong-Sun Kim ◽  
Hae-In Park ◽  
Sun-Woo Choi ◽  
Wook-Jin Oh ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Life Stress ◽  
Early Life ◽  
Early Life Stress ◽  
Borderline Personality ◽  
Emotional Dysregulation ◽  
Major Depressive ◽  
Stress Resilience

“Floating” MMPI Profiles and DSM-III Diagnoses

1983 ◽  
Vol 53 (3_suppl) ◽  
pp. 1119-1122
Author(s):  
Charles S. Newmark ◽  
Pamela Chassin ◽  
Lee Gentry ◽  
Dwight L. Evans
Keyword(s):  
Major Depressive Disorder ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Chart Review ◽  
Psychiatric Patients ◽  
Retrospective Chart Review ◽  
Borderline Personality ◽  
Major Depressive ◽  
Male Patients ◽  
A Prospective Study

DSM-III diagnoses of 55 hospitalized psychiatric male patients who produced “floating” MMPI profiles were obtained via retrospective chart review. A prospective study of 16 then was conducted to cross-validate the initial diagnostic findings The results from both investigations suggested that at least half of these hospitalized psychiatric patients received a DSM-III diagnosis of either borderline personality disorder or major depressive disorder. A paucity of schizophrenic diagnoses was noted.

Stress and the Brain

2018 ◽  
pp. 434-462
Author(s):  
Deanna M. Barch ◽  
David Pagliaccio
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Life Stress ◽  
Early Life ◽  
Diffusion Imaging ◽  
Early Life Stress ◽  
Resting State Functional Connectivity ◽  
Major Depressive ◽  
Brain Structure And Function ◽  
And Function

This chapter reviews associations between early life stress and brain structure and function as assessed by structural and functional magnetic resonance imaging. Particularly, this chapter focuses on structural associations in children and adults and the regional overlap with neural alterations observed in major depressive disorder, though we also more briefly cover diffusion imaging, task-based imaging, and resting-state functional connectivity. Major depressive disorder is highlighted given that early life stress is a critical risk factor for depression and the neural alterations observed with stress and depression may serve as key mediating factors of this association. A brief methodological overview is provided for each neuroimaging domain as well as a discussion of limitations and future directions for this field.

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