scholarly journals Epigenetic correlates of the psychological intervention outcomes: A systematic review and meta-analysis

Author(s):  
Pellicano Gaia Romana ◽  
Sambucini Daniela ◽  
Ciacchella Chiara ◽  
Giusti Arianna ◽  
Aceto Paola ◽  
...  
2019 ◽  
Author(s):  
Mathias Harrer ◽  
Sophia Helen Adam ◽  
Eva-Maria Messner ◽  
Harald Baumeister ◽  
Pim Cuijpers ◽  
...  

Background. Eating problems are highly prevalent among young adults. Universities could be an optimal setting to prevent eating disorders through psychological intervention. As part of the World Mental Health-International College Student initiative, this systematic review and meta-analysis synthesizes data on the efficacy of eating disorder prevention programs targeting university students.Method. A systematic literature search of bibliographical databases (CENTRAL, MEDLINE, PsycINFO) for randomized trials comparing psychological preventive interventions for eating disorders in university students to psychoeducation or inactive controls was performed through October 8th, 2018.Results. Twenty-two studies were included. Eight (36.4%) were rated to have a low risk of bias. The relative risk of developing a subthreshold or full-blown eating disorder was IRR=0.62 (95%CI: 0.44-0.87, n=8; standardized clinical interviews only), indicating a 38% decrease in incidence in the intervention groups compared to controls. Small to moderate between- group effects at post-test were found on self-reported global eating disorder symptoms (g=0.36, 95%CI: 0.25-0.47, n=20), dieting (g=0.47, 95%CI: 0.30- 0.64, n=18), body dissatisfaction (g=0.50, 95%CI: 0.33-0.67, n=14), drive for thinness (g=0.43, 95%CI: 0.27-0.59, n=12), weight concerns (g=0.33, 95%CI: 0.10-0.57, n=13) and affective symptoms (g=0.28, 95%CI: 0.16-0.40, n=14). Effects on bulimia were not significant. Heterogeneity was low to moderate across comparisons.Discussion. Eating disorder prevention on campus can have significant, small-to-moderate effects on eating disorder symptoms and risk factors. Results also suggest that the prevention of subthreshold and full-syndrome eating disorders is feasible using such interventions. More research is needed to identify effects on academic functioning, as well as ways to motivate students to use preventive eating disorder interventions.


2019 ◽  
Vol 49 (11) ◽  
pp. 1787-1798 ◽  
Author(s):  
Juan M. Flujas-Contreras ◽  
Azucena García-Palacios ◽  
Inmaculada Gómez

AbstractBackgroundParenting interventions have important consequences for the wellbeing and emotional competences of parents and their children. Technology provides an opportunity with advantages for psychological intervention. The aim of this systematic review and meta-analysis is to analyze the characteristics and effectiveness of technology-based interventions for parents to promote children's physical health or psychological issues.MethodsWe conducted a systematic review and meta-analysis for articles about parenting skills for prevention or treatment of children's physical or psychological concerns using technology. We explore the aim of the intervention with parents, kind of problem with children, intervention model, instruments, methodological quality, and risk of bias. A random-effects meta-analysis was conducted.ResultsTwenty-four studies were included in the systematic review and a meta-analysis of 22 studies was performed to find out the effects of intervention depending on the kind of problem, intervention model, follow-up, type of intervention, type of control condition, and type of outcome data. Results show the usefulness of technology-based therapy for parenting interventions with moderate effect sizes for intervention groups with statistically significant differences from control groups.ConclusionsTechnology-based parenting programs have positive effects on parenting and emotional wellbeing of parents and children. Attendance and participation level in technology-based treatment increase compared with traditional parenting intervention.


2019 ◽  
Vol 37 (31) ◽  
pp. 2899-2915 ◽  
Author(s):  
Nina M. Tauber ◽  
Mia S. O’Toole ◽  
Andreas Dinkel ◽  
Jacqueline Galica ◽  
Gerry Humphris ◽  
...  

PURPOSE Fear of cancer recurrence (FCR) is a significantly distressing problem that affects a substantial number of patients with and survivors of cancer; however, the overall efficacy of available psychological interventions on FCR remains unknown. We therefore evaluated this in the present systematic review and meta-analysis. METHODS We searched key electronic databases to identify trials that evaluated the effect of psychological interventions on FCR among patients with and survivors of cancer. Controlled trials were subjected to meta-analysis, and the moderating influence of study characteristics on the effect were examined. Overall quality of evidence was evaluated using the GRADE system. Open trials were narratively reviewed to explore ongoing developments in the field (PROSPERO registration no.: CRD42017076514). RESULTS A total of 23 controlled trials (21 randomized controlled trials) and nine open trials were included. Small effects (Hedges’s g) were found both at postintervention ( g = 0.33; 95% CI, 0.20 to 0.46; P < .001) and at follow-up ( g = 0.28; 95% CI, 0.17 to 0.40; P < .001). Effects at postintervention of contemporary cognitive behavioral therapies (CBTs; g = 0.42) were larger than those of traditional CBTs ( g = 0.24; β = .22; 95% CI, .04 to .41; P = .018). At follow-up, larger effects were associated with shorter time to follow-up (β = −.01; 95% CI, −.01 to −.00; P = .027) and group-based formats (β = .18; 95% CI, .01 to .36; P = .041). A GRADE evaluation indicated evidence of moderate strength for effects of psychological intervention for FCR. CONCLUSION Psychological interventions for FCR revealed a small but robust effect at postintervention, which was largely maintained at follow-up. Larger postintervention effects were found for contemporary CBTs that were focused on processes of cognition—for example, worry, rumination, and attentional bias—rather than the content, and aimed to change the way in which the individual relates to his or her inner experiences. Future trials could investigate how to further optimize and tailor interventions to individual patients’ FCR presentation.


Author(s):  
Leila BAGHERI ◽  
Ali Mohammad NAZARI ◽  
Reza CHAMAN ◽  
Ashraf GHIASI ◽  
Zahra MOTAGHI

Background: Abortion is the ending of pregnancy due to removing an embryo or fetus before it can survive outside the uterus. Some women suffer from psychological disorders such as anxiety, depression and grief after abortion. Early detection of high-risk women after abortion and psychological intervention is one of the healing methods than can lead to improving outcomes but its effectiveness is not clear. The present meta-analysis evaluated the efficacy of this approach. Methods: The international and national electronic databases were searched from Jan 1998 until Aug 2018 including Medline, Web of Knowledge, Ovid, Embase, PubMed, Scopus, Cochrane, ScienceDirect, PsycINFO, ProQuest, Google Scholar, Iranmedex, Scientific Information Database (SID), and Magiran. The pooled mean difference with the random-effects model was used for meta-analyses. The preferred reporting items for systematic reviews and meta-analyses guidelines adhered in this study. Results: We enrolled 7 relevant studies involving 918 subjects into the meta-analysis process. The metaanalysis of the interventions aiming at prevention of post-abortion grief yielded a pooled standardized mean difference (SMD) of −0.03 (95% CI: −0.40−0.34; Z=0.16; P=0.87) at post-test and of -0.21 (95% CI:-0.53- 0.10; Z=1.32; P=0.19) at follow-up. Conclusion: This systematic review found psychotherapy-based interventions are effective in post-abortion grief treatment but; we found psychotherapy-based interventions are somewhat effective in short-term postabortion grief and it has a better effect on long-term grief.


2020 ◽  
Vol 8 (1) ◽  
pp. e001150
Author(s):  
Kirsty Winkley ◽  
Rebecca Upsher ◽  
Daniel Stahl ◽  
Daniel Pollard ◽  
Alan Brennan ◽  
...  

The quality of evidence that psychological interventions are effective in improving glycemic control in adults with type 2 diabetes (T2D) is weak.We conducted a systematic review and meta-analysis of psychological interventions in T2D to assess whether their effectiveness in improving glycemic levels has improved over the past 30 years. We applied the protocol of a systematic review and aggregate meta-analysis conducted to January 2003. We added network meta-analysis (NMA) to compare intervention and control group type against usual care. MEDLINE, Cumulative Index to Nursing and Allied Health Literature, PsycINFO, EMBASE, Cochrane Controlled Trials Database, Web of Science, and Dissertation Abstracts International were searched from January 2003 to July 2018. Only randomized controlled trials (RCT) of psychological interventions for adults with T2D reported in any language were included. The primary outcome was change in glycemic control (glycated hemoglobin (HbA1c) in mmol/mol). Data were extracted from study reports and authors were contacted for missing data.94 RCTs were eligible for inclusion in the systematic review since the last review. In 70 RCTs (n=14 796 participants) the pooled mean difference in HbA1c in those randomized to psychological intervention compared with control group was −0.19 (95% CI −0.25 to −0.12), equivalent to a reduction in HbA1c of 3.7 mmol/mol, with moderate heterogeneity across studies (I2=64.7%, p<0.001). NMA suggested the probability of intervention effectiveness is highest for self-help materials, cognitive–behavioral therapy, and counseling, compared with usual care. Limitations of this study include that there is a possibility that some studies may have been missed if diabetes did not appear in the title or abstract.The effectiveness of psychological interventions for adults with T2D have minimal clinical benefit in improving glycemic control.PROSPERO registration numberCRD42016033619.


2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Naonori Yasuma ◽  
Zui Narita ◽  
Natsu Sasaki ◽  
Erika Obikane ◽  
Junpei Sekiya ◽  
...  

Abstract Background Prevention of antenatal and postnatal depression is crucial, given its high prevalence and severe consequences. Although several systematic reviews and meta-analyses have examined the effects of psychological interventions on the population at risk for perinatal depression, few studies have focused on universal prevention and none have focused specifically on universal prevention in pregnancy. The aim of this study is to examine the effects of psychological interventions with a universal prevention focus on perinatal depression during pregnancy by performing a systematic review and meta-analysis based on both the latest articles and a broader literature search. Methods The literature search will be conducted using the Cochrane Controlled Register of Trials (CENTRAL), Embase, PubMed and PsycINFO, from inception onwards. Randomized controlled trials that examined the association between psychological interventions and universal prevention of antenatal and postnatal depression among pregnant women will be included. Study selection, data collection, quality assessment, and statistical syntheses will be conducted following a priori defined methods in the protocol. Discussion The findings of this systematic review and meta-analysis will have both clinical and political importance in the context of perinatal mental health. In addition, this study will promote future studies and clarify the direction of research on universal prevention of perinatal depression. Systematic review registration PROSPERO CRD42019118041


2019 ◽  
Vol 10 (1) ◽  
pp. 1695486 ◽  
Author(s):  
Neil P. Roberts ◽  
Neil J. Kitchiner ◽  
Justin Kenardy ◽  
Catrin E. Lewis ◽  
Jonathan I. Bisson

Sign in / Sign up

Export Citation Format

Share Document