P2-168: Family history of non-Alzheimer's Demeutia memory problems predicts rate of cognitive decline in APOE E4 non-carriers in Alzheimer's disease: The Cache County Dementia Progression Study.

2011 ◽  
Vol 7 ◽  
pp. S366-S366
Author(s):  
JoAnn Tschanz ◽  
Daniel Hatch ◽  
Stephanie Croasdell ◽  
Joseph Wanzek ◽  
John Kauwe ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Family History ◽  
Cognitive Decline ◽  
Memory Problems ◽  
History Of ◽  
Cache County

scholarly journals PERSONALITY AND FAMILY HISTORY OF ALZHEIMER’S DISEASE AS PREDICTORS OF OLDER ADULTS’ SELF-REPORTED MEMORY PROBLEMS

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S220-S220
Author(s):  
Sakshi Bhargava ◽  
Nikki Hill ◽  
Jacqueline Mogle ◽  
Tyler R Bell ◽  
Rachel Wion
Keyword(s):  
Alzheimer’S Disease ◽  
Older Adults ◽  
Alzheimer's Disease ◽  
Family History ◽  
Multilevel Modeling ◽  
Individual Factors ◽  
Memory Decline ◽  
Memory Problems ◽  
History Of ◽  
One Year

Abstract Understanding individual factors (e.g., personality) associated with self-reported memory problems is important to refine identification of individuals at a higher risk of developing Alzheimer’s disease (AD). Using multilevel modeling, we examined the association of family history of AD and personality traits with self-reported memory problems in older adults (n = 421; 72.21% White; 62.95% female; Mage = 76.69). Results showed that individuals with a family history of AD reported more frequent memory problems and greater one-year memory decline. Similar findings were reported for individuals with higher extraversion scores. Further, older adults with higher neuroticism scores reported greater one- and ten-year memory decline. Neuroticism was positively related to frequency of memory problems, but only among participants with a family history of AD. Findings suggest that higher neuroticism and lower extraversion may increase older adults’ reports of memory problems. Family history of AD may further exacerbate this tendency.

Mnemonics Usage and Cognitive Decline in Age-Associated Memory Impairment

1997 ◽  
Vol 9 (1) ◽  
pp. 47-56 ◽  
Author(s):  
Gary W. Small ◽  
Asenath La Rue ◽  
Scott Komo ◽  
Andrea Kaplan
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Family History ◽  
Cognitive Decline ◽  
Memory Impairment ◽  
Memory Function ◽  
Subjective Memory ◽  
Memory Measure ◽  
History Of

To determine predictors of cognitive deterioration, the authors performed baseline and 1- to 5-year follow-up (mean ± SD = 2.5 ± 1.2 years) neuropsychological assessments on 36 persons (mean age ± SD = 62.1 ± 8.0; range = 50 to 81 years) with age-associated memory impairment. Subjects were recruited from a larger group of volunteers, had minimal medical comorbidity, and 25 of them had a family history of Alzheimer's disease. Baseline age and a subjective memory measure indicating reported frequency of mnemonics usage were significant decline predictors. Subjects reporting more frequent mnemonics use at baseline were more likely to show objective cognitive decline at follow-up. Baseline full-scale IQ, educational level, and family history of Alzheimer's disease failed to predict decline. These findings suggest that although age is the strongest decline predictor in some people with age-associated memory impairment, self-perception of memory function may also predict subsequent cognitive loss.

O3-03-08: The association between family history of Alzheimer's disease, APOE status, and cognitive decline

2008 ◽  
Vol 4 ◽  
pp. T164-T165
Author(s):  
Kathleen M. Hayden ◽  
Peter P. Zandi ◽  
Nancy A. West ◽  
JoAnn T. Tschanz ◽  
Maria C. Norton ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Family History ◽  
Cognitive Decline ◽  
History Of

scholarly journals P4-573: PROXIMITY TO PARENTAL ONSET AND APOE ε4 INDEPENDENTLY CONTRIBUTE TO AMYLOID BURDEN IN MIDDLE-AGED ADULTS WITH A FAMILY HISTORY OF SPORADIC ALZHEIMER'S DISEASE

2019 ◽  
Vol 15 ◽  
pp. P1539-P1539
Author(s):  
Eider M. Arenaza-Urquijo ◽  
Gemma Salvadó ◽  
Carolina Minguillón ◽  
Marta Crous-Bou ◽  
Gonzalo Sánchez-Benavides ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Family History ◽  
Amyloid Burden ◽  
Middle Aged ◽  
Sporadic Alzheimer’S Disease ◽  
Apoe Ε4 ◽  
History Of ◽  
Middle Aged Adults
Sign in / Sign up

Export Citation Format

Share Document