P1-356: DEMENTIA OCCURRENCE IN PEOPLE WITH COGNITIVE IMPAIRMENT AND SLOW WALKING SPEED: A 9-YEAR LONG POPULATION-BASED STUDY

AbstractWith the aging of the population, vision (VL), hearing (HL), and dual-sensory (DSL, concurrent VL and HL) loss will likely constitute important public health challenges. Walking speed is an indicator of functional status and is associated with mortality. Using the Health and Retirement Study, a nationally representative U.S. cohort, we analyzed the longitudinal relationship between sensory loss and walking speed. In multivariable mixed effects linear models, baseline walking speed was slower by 0.05 m/s (95% confidence interval [CI] = 0.04–0.07) for VL, 0.02 (95% CI = 0.003–0.03) for HL, and 0.07 (95% CI = 0.05–0.08) for DSL compared with those without sensory loss. Similar annual declines in walking speeds occurred in all groups. In time-to-event analyses, the risk of incident slow walking speed (walking speed < 0.6 m/s) was 43% (95% CI = 25–65%), 29% (95% CI = 13–48%), and 35% (95% CI = 13–61%) higher among those with VL, HL, and DSL respectively, relative to those without sensory loss. The risk of incident very slow walking speed (walking speed < 0.4 m/s) was significantly higher among those with HL and DSL relative to those without sensory loss, and significantly higher among those with DSL relative to those with VL or HL alone. Addressing sensory loss and teaching compensatory strategies may help mitigate the effect of sensory loss on walking speed.

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Clinical features of incidental mild cognitive impairment and dementia in a population-based study

Geriatrics and Gerontology International ◽

10.1111/ggi.12778 ◽

2016 ◽

Vol 17 (5) ◽

pp. 722-729 ◽

Cited By ~ 3

Author(s):

Nozomi Hishikawa ◽

Yusuke Fukui ◽

Kota Sato ◽

Toru Yamashita ◽

Yasuyuki Ohta ◽

...

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Clinical Features ◽

Population Based ◽

Population Based Study

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Relationship of an advanced glycation end product, plasma carboxymethyl-lysine, with slow walking speed in older adults: the InCHIANTI study

European Journal of Applied Physiology ◽

10.1007/s00421-009-1192-5 ◽

2009 ◽

Vol 108 (1) ◽

pp. 191-195 ◽

Cited By ~ 51

Author(s):

Richard D. Semba ◽

Stefania Bandinelli ◽

Kai Sun ◽

Jack M. Guralnik ◽

Luigi Ferrucci

Keyword(s):

Older Adults ◽

Walking Speed ◽

Advanced Glycation ◽

Advanced Glycation End Product ◽

Slow Walking ◽

Carboxymethyl Lysine ◽

Relationship Of ◽

Slow Walking Speed

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PREVALENCE OF MILD COGNITIVE IMPAIRMENT AND DEMENTIA IN OLDER NON-WESTERN IMMIGRANTS IN THE NETHERLANDS: A POPULATION-BASED STUDY

The Gerontologist ◽

10.1093/geront/gnv313.03 ◽

2015 ◽

Vol 55 (Suppl_2) ◽

pp. 602-603

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

The Netherlands ◽

Population Based ◽

Population Based Study

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Mild Cognitive Impairment that Does Not Progress to Dementia: A Population-Based Study

Journal of the American Geriatrics Society ◽

10.1111/jgs.15642 ◽

2018 ◽

Vol 67 (2) ◽

pp. 232-238 ◽

Cited By ~ 13

Author(s):

Mary Ganguli ◽

Yichen Jia ◽

Tiffany F. Hughes ◽

Beth E. Snitz ◽

Chung-Chou H. Chang ◽

...

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Population Based ◽

Population Based Study

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Associations between locomotive and non-locomotive physical activity and physical performance in older community-dwelling females with and without locomotive syndrome: a cross-sectional study

Journal of PHYSIOLOGICAL ANTHROPOLOGY ◽

10.1186/s40101-021-00268-8 ◽

2021 ◽

Vol 40 (1) ◽

Author(s):

Tomohiro Nishimura ◽

Atsushi Hagio ◽

Kanako Hamaguchi ◽

Toshiyuki Kurihara ◽

Motoyuki Iemitsu ◽

...

Keyword(s):

Physical Activity ◽

Walking Speed ◽

Cross Sectional Study ◽

Community Dwelling ◽

Step Test ◽

Locomotive Syndrome ◽

Sectional Study ◽

Cross Sectional ◽

Slow Walking ◽

Slow Walking Speed

Abstract Background Locomotive syndrome (LS) is a condition of reduced mobility due to a disorder of the locomotive system. Increasing moderate to vigorous physical activity (MVPA) has been recommended to prevent LS. However, to increase daily MVPA is difficult for older people with LS. The MVPA consists of not only locomotive activities such as walking but also non-locomotive activities such as household activities. The aim of this study was to examine the associations between locomotive/non-locomotive MVPA and physical performance in older females with and without LS. Methods Participants of this cross-sectional study were 143 older community-dwelling Japanese females. The participants were divided into two groups based on the results of the stand-up test: the normal group (NL) (n = 86) and the LS group (n = 57). Both the locomotive and non-locomotive PA seperately measured with its intensity. The intensity of physical activity (PA) was calculated as METs and classified as sedentary behavior (SB 1–1.5 metabolic equivalent tasks (METs)), low-intensity physical activity (LPA 1.6–2.9 METs), and MVPA (≥ 3 METs). For example, locomotive LPA is slow walking speed of 54 m/min, and locomotive MVPA is walking speed of 67 m/min. While non-locomotive LPA is office work and cooking, non-locomotive MVPA is housecleaning. Physical function was evaluated by handgrip strength, walking speed, and 2-step test. Results Walking speed, hand-grip strength, 2-step test, daily step counts, and all PA measurements were not significantly different between two groups. In the LS, locomotive MVPA (r = 0.293, p < 0.05) and total MVPA (r = 0.299, p < 0.05) was significantly correlated with walking speed, but not in the NL. Conclusions Walking speed was positively correlated with locomotive MVPA and total MVPA in the LS group, but not in NL group. This result suggests that slow walking speed in older people with LS occur in connection with lower locomotive MVPA and total MVPA.

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Prevalence, risk and protective factors for mild cognitive impairment in a population-based study of Singaporean elderly

Journal of Psychiatric Research ◽

10.1016/j.jpsychires.2021.11.041 ◽

2021 ◽

Author(s):

Ling-Yun Liu ◽

Yanxia Lu ◽

Liang Shen ◽

Chun-Bo Li ◽

Jin-Tai Yu ◽

...

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Protective Factors ◽

Risk And Protective Factors ◽

Population Based ◽

Population Based Study

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Disparities in Subjective Cognitive Impairment by Sexual Orientation and Gender in a National Population Based Study of U.S. Adults, 2013–2018

Journal of Aging and Health ◽

10.1177/08982643211046466 ◽

2021 ◽

pp. 089826432110464

Author(s):

Karen I. Fredriksen-Goldsen ◽

Hailey Jung ◽

Hyun-Jun Kim ◽

Ryan Petros ◽

Charles Emlet

Keyword(s):

Cognitive Impairment ◽

Sexual Orientation ◽

Sexual Minority ◽

Sexual Minorities ◽

Population Based ◽

Population Based Study ◽

Subjective Cognitive Impairment ◽

Targeted Interventions ◽

National Population ◽

And Gender

Objectives: This is the first national population-based study to examine cognitive impairment disparities among sexual minority mid-life and older adults. Methods: Using the National Health Interview Survey (2013–2018), we compared weighted prevalence of subjective cognitive impairment by sexual orientation and gender, among those aged 45 plus, applying logistic regressions adjusting for age, income, education, race/ethnicity, and survey years. Results: Sexual minorities (24.5%) were more likely to have subjective cognitive impairment than heterosexuals (19.1%). Sexual minority women had higher odds of greater severity, frequency, and extent of subjective cognitive impairment. Sexual minorities were also more likely to report activity limitations resulting from cognitive impairment and were no more likely to attribute limitations to dementia or senility. Discussion: Cognitive health disparities are of particular concern in this historically and socially marginalized population. The investigation of explanatory factors is needed, and targeted interventions and policies are warranted to address cognitive challenges faced by sexual minorities.

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