scholarly journals P1-575: PRE-INJURY MILD COGNITIVE IMPAIRMENT IN OLDER ADULTS PRESENTING ACUTELY WITH TRAUMATIC BRAIN INJURY: THE TRANSFORMING RESEARCH AND CLINICAL KNOWLEDGE IN GERIATRIC TBI PILOT STUDY (TRACK-GERI PILOT)

2019 ◽  
Vol 15 ◽  
pp. P496-P496
Author(s):  
Michele Diaz ◽  
Chelsea Camara ◽  
Molly Rose Morrissey ◽  
Geoffrey T. Manley ◽  
Raquel C. Gardner
2015 ◽  
Vol 5 (1) ◽  
pp. 51-63 ◽  
Author(s):  
Kerry L. Hildreth ◽  
Rachael E. Van Pelt ◽  
Kerrie L. Moreau ◽  
Jim Grigsby ◽  
Karin F. Hoth ◽  
...  

Aims: To examine the effects of pioglitazone or endurance exercise training on cognitive function in older adults with mild cognitive impairment (MCI) and insulin resistance. Methods: Seventy-eight adults (mean age ± SD: 65 ± 7 years) with central obesity and MCI were randomized to 6 months of endurance exercise, pioglitazone or control. Results: Sixty-six participants completed the study. Exercise training did not significantly increase peak oxygen uptake compared to control (p = 0.12). Compared to control, insulin resistance improved in the pioglitazone group (p = 0.002) but not in the exercise group (p = 0.25). There was no measureable effect of pioglitazone or exercise on cognitive performance compared to control. Conclusion: In this pilot study, pioglitazone improved insulin resistance but not cognitive performance in older adults with MCI and insulin resistance.


2016 ◽  
Vol 51 (3) ◽  
pp. 727-736 ◽  
Author(s):  
Christian LoBue ◽  
David Denney ◽  
Linda S. Hynan ◽  
Heidi C. Rossetti ◽  
Laura H. Lacritz ◽  
...  

2016 ◽  
Vol 263 (7) ◽  
pp. 1280-1285 ◽  
Author(s):  
Wei Li ◽  
Shannon L. Risacher ◽  
Thomas W. McAllister ◽  
Andrew J. Saykin

2015 ◽  
Vol 11 (7S_Part_9) ◽  
pp. P444-P444
Author(s):  
Munro Cullum ◽  
Christian Lobue ◽  
David Denney ◽  
Linda Hynan ◽  
Heidi Rossetti ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document