Efficient intracellular siRNA delivery strategy through rapid and simple two steps mixing involving noncovalent post-PEGylation

2009 ◽  
Vol 138 (2) ◽  
pp. 141-147 ◽  
Author(s):  
Won-Ho Kong ◽  
Dong-Kyung Sung ◽  
Yong-Ho Shim ◽  
Ki Hyun Bae ◽  
Philippe Dubois ◽  
...  
Keyword(s):  
Sirna Delivery ◽  
Delivery Strategy

scholarly journals Novel siRNA delivery strategy: a new “strand” in CNS translational medicine?

2013 ◽  
Vol 71 (1) ◽  
pp. 1-20 ◽  
Author(s):  
Lisa Gherardini ◽  
Giuseppe Bardi ◽  
Mariangela Gennaro ◽  
Tommaso Pizzorusso
Keyword(s):  
Translational Medicine ◽  
Sirna Delivery ◽  
Delivery Strategy

Optimization of a synthetic siRNA delivery for the treatment of rhabdomyosarcoma

2008 ◽  
Vol 3 (4) ◽  
pp. 371-379 ◽  
Author(s):  
Ewa Lesko ◽  
Katarzyna Miekus ◽  
Agnieszka Grabowska ◽  
Aleksandra Gładys ◽  
Marcin Majka
Keyword(s):  
Gene Silencing ◽  
Small Interfering Rna ◽  
Target Gene ◽  
Target Genes ◽  
Sirna Delivery ◽  
Basic Research ◽  
Delivery Strategy ◽  
Therapeutic Benefits ◽  
Interfering Rna

AbstractSilencing of a target-genes by small interfering RNA (siRNA) has emerged as a powerful new tool not only for basic research but also with potential therapeutic benefits. This paper demonstrates that optimal delivery strategy is crucial for effective target-gene silencing. Using lipofection, under defined conditions, we were able to markedly down-regulate expression of the selected genes involved in rhabdomyosarcoma metastasis: MET, CXCR4, LIFR and PAX3-FKHR.

Polymersomes-mediated siRNA delivery for states of hormone excess

2013 ◽  
pp. 1-1
Author(s):  
Georgia Bakirtzi ◽  
Giuseppe Battaglia ◽  
Giuseppe Battaglia ◽  
John Price Newell
Keyword(s):  
Sirna Delivery

Lipid-based siRNA Delivery Systems

2012 ◽  
Vol 39 (5) ◽  
pp. 396-401 ◽  
Author(s):  
Wen-Juan DONG ◽  
Yin-Jian ZHOU ◽  
Wei LIANG
Keyword(s):  
Sirna Delivery ◽  
Delivery Systems
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