Long-term outcome of excimer laser phototherapeutic keratectomy for treatment of Salzmannʼs nodular degeneration

PurposeTo evaluate long-term outcome of femtosecond laser-assisted lamellar keratectomy (FLK) with phototherapeutic keratectomy (PTK) in patients with anterior corneal stromal dystrophies.MethodsA total of 10 eyes from seven patients who underwent FLK were included. The patients had suffered from recurrent corneal erosion or visual disturbance in anterior corneal dystrophies (five Avellino dystrophies and two lattice dystrophies). Planar-shaped lamellar keratectomy was performed using femtosecond laser. The amount of corneal excision was determined by the depth of corneal opacity. Additional PTK with mitomycin C application was performed for smoothening of corneal cut surface. The patients were evaluated with following parameters: uncorrected visual acuity, best-corrected visual acuity (BCVA), mean anterior keratometric value, corneal irregularity, corneal high-order aberrations (HOA) and the recurrence of corneal erosion.ResultsMean duration of follow-up was 64 months (2.5–9.5 years). The BCVA improved more than two lines of Snellen chart at last visit. The changes of keratometric values were within ±1 D in eight out of 10 eyes. Corneal irregularities in central 5 mm cornea and the values of total corneal HOA in central 6 mm cornea decreased by 0.3–3.1 D and 0.01–2.2 µm, respectively. Corneal erosion did not recur in any of those patients during follow-up and corneal dystrophy did not recur in eight out of 10 eyes.ConclusionIn anterior corneal stromal dystrophies, FLK with PTK can be an effective surgical option to improve VA through decreasing corneal irregularities and HOA, while minimising corneal curvature changes.

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THE IMPACT OF THE ABLATION BY EXCIMER LASER SYSTEM ON THE LONG-TERM OUTCOME IN IN-STENT RESTENOSIS

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(19)31714-0 ◽

2019 ◽

Vol 73 (9) ◽

pp. 1107

Author(s):

Takao Sato ◽

Keiichi Tsuchida ◽

Sho Yuasa ◽

Yuji Taya ◽

Masaaki Okabe ◽

...

Keyword(s):

Excimer Laser ◽

Laser System ◽

Term Outcome ◽

Long Term Outcome ◽

Stent Restenosis ◽

The Impact ◽

In Stent Restenosis

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Comparison of Percent Tissue altered in Topography Guided and Wavefront Optimized Laser-assisted in situ Keratomileusis using Zeiss MEL 80 Excimer Laser

Nepalese Journal of Ophthalmology ◽

10.3126/nepjoph.v13i2.26665 ◽

2021 ◽

Vol 13 (2) ◽

pp. 69-76

Author(s):

Shwetambari Singh ◽

Neha Shilpy ◽

Dipali Purohit ◽

Zalak Shah

Keyword(s):

Excimer Laser ◽

Visual Outcome ◽

Laser Materials ◽

Term Outcome ◽

Long Term Outcome ◽

Group I ◽

Tissue Alteration ◽

Group Ii

Introduction: Laser-assisted in situ Keratomileusis (LASIK) is the most commonly performed refractive surgical procedure. The amount of tissue ablated in LASIK affects the safety and long-term outcome. The objective of this study was to compare the percent tissue altered (PTA) in topography guided (TG) and wavefront optimized (WFO) LASIK using Zeiss MEL 80 excimer laser. Materials and methods: This retrospective observational study was conducted at a tertiary eye center. Patients with moderate myopia who underwent LASIK between June 2016 and January 2019 were divided into two groups (Group I: TG LASIK, 69 eyes; Group II: WFO LASIK, 70 eyes). The groups were compared for preoperative parameters [spherical equivalent (SE), keratometry and pachymetry], intraoperative parameters [ablation depth (AD), PTA and residual stromal bed thickness (RSBT)] and postoperative parameters (vision, SE). Results: Among preoperative parameters, SE and keratometry were similar while thinnest pachymetry was significantly less in group I. Among the intraoperative parameters, PTA (P < 0.01) and AD (P < 0.01) were significantly less in group I while RSBT (P = 0.54) was not significantly different. Postoperatively at 6 months, 92.75% (64) eyes in group I and 90% (63) eyes in group II had visual acuity of 6/6 or better (P = 0.57). 98.55% (68) and 97.14% (68) eyes in group I and group II respectively had SE refraction within ± 0.5 dioptres. Conclusion: TG LASIK induces less tissue alteration for given refractive error with similar visual outcome as compared to WFO LASIK which makes TG apparently safer and is the preferred technique for borderline thin corneas.

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