towards stem cell therapy of polycystic ovary syndrome (PCOS): therapeutic effect of human mesenchymal stem cells transplantation in pcos mouse model by regulating ovarian vascularization

Cytotherapy ◽  
2019 ◽  
Vol 21 (5) ◽  
pp. S78
Author(s):  
H. Park ◽  
D. Ashour ◽  
A. Elsharoud ◽  
R. Chugh ◽  
A. Al-Hendy ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Polycystic Ovary Syndrome ◽  
Mouse Model ◽  
Cell Therapy ◽  
Polycystic Ovary ◽  
Human Mesenchymal Stem Cells ◽  
Ovary Syndrome ◽  
Stem Cells Transplantation

scholarly journals Journey of Mesenchymal Stem Cells for Homing: Strategies to Enhance Efficacy and Safety of Stem Cell Therapy

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Sung Keun Kang ◽  
Il Seob Shin ◽  
Myung Soon Ko ◽  
Jung Youn Jo ◽  
Jeong Chan Ra
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Human Mesenchymal Stem Cells ◽  
Cellular Damage ◽  
Efficacy And Safety ◽  
Clinical Benefits

Human mesenchymal stem cells (MSCs) communicate with other cells in the human body and appear to “home” to areas of injury in response to signals of cellular damage, known as homing signals. This review of the state of current research on homing of MSCs suggests that favorable cellular conditions and thein vivoenvironment facilitate and are required for the migration of MSCs to the site of insult or injuryin vivo. We review the current understanding of MSC migration and discuss strategies for enhancing both the environmental and cellular conditions that give rise to effective homing of MSCs. This may allow MSCs to quickly find and migrate to injured tissues, where they may best exert clinical benefits resulting from improved homing and the presence of increased numbers of MSCs.

scholarly journals Use of Photobiomodulation and Mesenchymal Stem Cells in Polycystic Ovary Syndrome‐Induced Rats

2019 ◽  
Vol 33 (S1) ◽  
Author(s):  
Eduardo Donato Alves ◽  
Luíz Guilherme Dércore Benevenuto ◽  
Rebeca Gall Amin ◽  
João Antônio Donadoni ◽  
Kamile Bausells Ferrari ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome

scholarly journals Instant stem cell therapy: Characterization and concentration of human mesenchymal stem cells in vitro

2008 ◽  
Vol 16 ◽  
pp. 47-55 ◽  
Author(s):  
P Kasten ◽  
◽  
I Beyen ◽  
M Egermann ◽  
AJ Suda ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Human Mesenchymal Stem Cells

scholarly journals Mesenchymal stem cell applications in polycystic ovary syndrome treatment

2021 ◽  
Vol 38 (3) ◽  
pp. 361-366
Author(s):  
Mehmet Volkan BULBUL ◽  
Berna YILDIRIM ◽  
Bircan KOLBASI ◽  
İlknur KESKIN
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Polycystic Ovary Syndrome ◽  
Spinal Cord Injuries ◽  
Polycystic Ovary ◽  
Experimental Studies ◽  
Tooth Pulp ◽  
Therapeutic Effects ◽  
Ovary Syndrome ◽  
Paracrine Factors

Mesenchymal stem cells (MSCs) are highly capable of self-renewal and differentiation. They can be isolated from a variety of sources such as adipose tissue, bone marrow, umbilical cord, tooth pulp and can be cultured under in vitro conditions. MSCs have anti-inflammatory, anti-apoptotic, angiogenic, immunomodulatory and many more therapeutic effects due to the effects of paracrine factors they secrete. Today, mesenchymal stem cells are used for treatment in more than twenty diseases, from spinal cord injuries to diabetes. However, there is little mention in the literature of the use of these cells in female reproductive system diseases. In this review, a limited number of clinical and experimental studies on the use of mesenchymal stem cells in the treatment of polycystic ovary syndrome, which is very common in women, were examined and analyzed.

Human mesenchymal stem cells promote survival and prevent intestinal damage in a mouse model of radiation injury

RSC Advances ◽  
2016 ◽  
Vol 6 (69) ◽  
pp. 65105-65111 ◽  
Author(s):  
Meng-Zheng Guo ◽  
Wei Gong ◽  
Hong-Wei Zhang ◽  
Yan Wang ◽  
Li-Qing Du ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Mouse Model ◽  
Radiation Injury ◽  
Human Mesenchymal Stem Cells ◽  
Intestinal Stem Cell ◽  
Human Umbilical Cord ◽  
Intestinal Damage ◽  
Protective Effects

In the present study, we examined the protective effects of human umbilical cord mesenchymal stem cells (hMSCs) against intestinal stem cell (ISC) death and intestinal damage in a mouse model of radiation injury.

scholarly journals Amide-Type Local Anesthetics and Human Mesenchymal Stem Cells: Clinical Implications for Stem Cell Therapy

2014 ◽  
Vol 3 (3) ◽  
pp. 365-374 ◽  
Author(s):  
Ryan C. Dregalla ◽  
Nicolette F. Lyons ◽  
Patrick D. Reischling ◽  
Christopher J. Centeno
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Local Anesthetics ◽  
Human Mesenchymal Stem Cells ◽  
Clinical Implications
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