Development and characterization of enteric coated pectin pellets containing mesalamine and Saccharomyces boulardii for specific inflamed colon: In vitro and in vivo evaluation

2021 ◽  
Vol 62 ◽  
pp. 102393
Author(s):  
Amandeep Singh ◽  
Uttam Kumar Mandal ◽  
Raj Kumar Narang
2008 ◽  
Vol 70 (1) ◽  
pp. 302-312 ◽  
Author(s):  
A DUKICOTT ◽  
T DEBEER ◽  
J REMON ◽  
W BAEYENS ◽  
P FOREMAN ◽  
...  

2009 ◽  
Vol 19 (6) ◽  
pp. 1553-1559 ◽  
Author(s):  
C. Thomas ◽  
O. Patschan ◽  
D. Ketelsen ◽  
I. Tsiflikas ◽  
A. Reimann ◽  
...  

2014 ◽  
Vol 40 (5) ◽  
pp. 890-903 ◽  
Author(s):  
Younes Majdouline ◽  
Jacques Ohayon ◽  
Zahra Keshavarz-Motamed ◽  
Marie-Hélène Roy Cardinal ◽  
Damien Garcia ◽  
...  

2021 ◽  
Vol 17 (5) ◽  
pp. 889-900
Author(s):  
Cuizhen Sun ◽  
Dianju He ◽  
Yonghua Qi ◽  
Guiqin Zhang ◽  
Qiujin Huang

In the current study, we hypothesized that the electrospun scaffold chitosan (CS)/polycaprolactone (PCL)/titanium dioxide (TiO2) could be prepared by combining CS, PCL, and TiO2 nanoparticles (TiO2 NPs) using an electrospinning technique for wound dressing applications. The CS/PCL/TiO2 electrospun scaffold was prepared and characterized by UV-Vis, SEM, TEM, FTIR, and XRD analyses. Based on the UV-Vis analysis, the incorporation of CS/PCL on the surface of TiO2 NPs affected their optical properties. Further, CS/PCL and CS/PCL/TiO2 were found to have uniform distribution in fiber diameter with no bead morphology, as confirmed by SEM. The XRD spectrum of the CS/PCL/TiO2 revealed that the TiO2 NPs were adequately mixed with the CS/PCL solution, exhibiting the planes of TiO2 peaks (112), (105), (204), (116), and (301), which aligned well with the lattice structure. The antibacterial activity of CS/PCL/TiO2 against Staphylococcus aureus and Escherichia coli was evaluated using the zone of inhibition method. By testing the cytocompatibility of CS/PCL/TiO2 in vitro, this dressing was found to have a less toxic nature. In addition, In Vivo wound healing studies showed that the dressing prepared with the CS/PCL/TiO2 electrospun scaffold improved wound healing compared to that prepared with CS/PCL alone. The above results strongly support the use of CS/PCL/TiO2 electrospun scaffold as an effective dressing for wound healing.


2012 ◽  
Vol 13 (3) ◽  
pp. 934-943 ◽  
Author(s):  
B. M. Ursekar ◽  
P. S. Soni ◽  
Abhijit A. Date ◽  
M. S. Nagarsenker

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