Seasonal occurrence and risk assessment of pharmaceutical and personal care products in Bengaluru rivers and lakes, India

Author(s):  
Chikmagalur Mallappa Gopal ◽  
Krishnamurthy Bhat ◽  
Babu Rajendran Ramaswamy ◽  
Virendra Kumar ◽  
Rakesh Kumar Singhal ◽  
...  
2018 ◽  
Vol 35 (11) ◽  
pp. 1263-1272 ◽  
Author(s):  
Alinne Mizukawa ◽  
Gabriela Reichert ◽  
Tais Cristina Filippe ◽  
Franciane de Almeida Brehm ◽  
Júlio César Rodrigues de Azevedo

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Heba Shaaban ◽  
Wejdan Alhajri

Reliable data regarding the usage patterns of personal care products (PCPs) are needed to determine the health risks posed by the ingredients of these products such as parabens, phthalates, and bisphenol A. There are no published data regarding the consumption patterns of PCPs in the Middle East in general and in Saudi Arabia in particular. To fill this gap, this study aimed to assess important factors such as the percentage of users and the frequency of use and co-use of twenty-three cosmetic and PCPs among the female population in Saudi Arabia. Additionally, this study aimed to assess the common cosmetic-related adverse events among the participants. The studied products included general hygiene, hair care, skin care, makeup, fragrances, and other products. The data were collected from 709 female participants of different age groups through a digital questionnaire. It was found that eighteen of the investigated products are consumed by at least 50% of the respondents. The frequency of use of PCPs varied over a wide range. Cosmetic-related adverse events were experienced by 16.1% of the participants. Use frequencies of many hygiene and makeup products were correlated with each other. This study provides, for the first time, baseline data on the usage patterns of a large number of widely consumed PCPs among female population pertaining to several sociodemographic strata. Such information is crucial for exposure and risk assessment and also needed for updating the current knowledge on usage of PCPs in Saudi Arabia.


2014 ◽  
Vol 470-471 ◽  
pp. 1078-1086 ◽  
Author(s):  
Feng Chen ◽  
Guang-Guo Ying ◽  
Yi-Bing Ma ◽  
Zhi-Feng Chen ◽  
Hua-Jie Lai ◽  
...  

2016 ◽  
Vol 38 (6) ◽  
pp. 634-645 ◽  
Author(s):  
S. E. Stewart ◽  
M. D. Parker ◽  
A. Amézquita ◽  
T. L. Pitt

2020 ◽  
Author(s):  
Xu Li ◽  
Wenping Zhang ◽  
Jiapei Lv ◽  
Wenxiu Liu ◽  
Shanwei Sun ◽  
...  

Abstract Background: Phthalates were detected in various environments due to their widespread application. In this study, indoor dust samples from 94 buildings, including 72 residences and 22 dormitories, were collected in seven geographical regions in China and analyzed for eight phthalate esters (PAEs). Investigation of contamination profiles, geographical distribution, sources and risks of PAEs in indoor dusts was explored.Results: The highest Σ8PAEs concentration in residential buildings was found in Northeast China (median: 164.71 μg·g−1), which was 2.3 and 2.8 times higher than that in South China (median: 71.71 μg·g−1) and Southwest China (median: 58.53 μg·g−1), respectively. Di(2-ethylhexyl) phthalate (DEHP), di-iso-butyl phthalate (DIBP), and di-n-butyl phthalate (DBP) were the dominant compounds of Σ8PAEs in indoor dusts from residences and dormitories. The administrative levels revealed that the highly serious contamination occurred in the provincial capital, followed by non-provincial cities and countries. Such an occurrence was related to the usage of PAE products and the level of urbanization. Principal component analysis and positive matrix factorization showed that the emission from cosmetics and personal care products, plasticizers, and household building materials were the possible PAE sources in indoor dusts. Among three routes of ingestion, dermal adsorption, and inhalation, dust ingestion was the main route of human exposure to PAEs. The health risk of PAE exposure for different populations decreased in the order of children > women > men. The hazard indexes of non-cancer were higher than the threshold value of 10−6 during human exposure to DBP and DEHP. Children also faced potential non-cancer risk due to benzyl butyl phthalate (BBzP) and di-n-octyl phthalate (DnOP) exposure. The carcinogenic risks via exposure to BBzP and DEHP were low and negligible.Conclusion: Overall, PAEs were widely presented in indoor dusts. Obvious difference was observed in the distribution of PAEs concentration in indoor dusts due to the differences in economic development and usage of PAEs product. Plasticizers, household building materials, and cosmetics and personal care products were likely PAE sources in indoor dusts. The risk assessment suggested that carcinogenic risks of BBzP and DEHP were negligible, but DBP, DEHP, DnOP and BBzP may pose non-cancer risks to humans.


2021 ◽  
Author(s):  
Xu Li ◽  
Wenping Zhang ◽  
Jiapei Lv ◽  
Wenxiu Liu ◽  
Shanwei Sun ◽  
...  

Abstract Background: Phthalates were detected in various environments due to their widespread application. In this study, indoor dust samples from 94 buildings, including 72 residences and 22 dormitories, were collected in seven geographical regions in China and analyzed for eight phthalate esters (PAEs). Investigation of contamination profiles, geographical distribution, sources and risks of PAEs in indoor dusts was explored.Results: The highest Σ8PAEs concentration in residential buildings was found in Northeast China (median: 164.71 μg·g−1), which was 2.3 and 2.8 times higher than that in South China (median: 71.71 μg·g−1) and Southwest China (median: 58.53 μg·g−1), respectively. Di(2-ethylhexyl) phthalate (DEHP), di-iso-butyl phthalate (DIBP), and di-n-butyl phthalate (DBP) were the dominant compounds of Σ8PAEs in indoor dusts from residences and dormitories. The administrative levels revealed that the highly serious contamination occurred in the provincial capital, followed by non-provincial cities and countries. Such an occurrence was related to the usage of PAE products and the level of urbanization. Principal Component Analysis (PCA) and Positive Matrix Factorization (PMF) showed that the emission from cosmetics and personal care products, plasticizers, and household building materials were the possible PAE sources in indoor dusts. Among three routes of ingestion, dermal adsorption, and inhalation, dust ingestion was the main route of human exposure to PAEs. The health risk of PAE exposure for different populations in descending order of children > women > men. The hazard indexes of non-cancer were higher than the threshold value of 10−6 during human exposure to DBP and DEHP. Children also faced potential non-cancer risk due to benzyl butyl phthalate (BBzP) and di-n-octyl phthalate (DnOP) exposure. The carcinogenic risks via exposure to BBzP and DEHP were negligible.Conclusion: Overall, PAEs were widely presented in indoor dusts. Obvious difference was observed in the distribution of PAEs concentration in indoor dusts due to the differences in economic development and usage of PAEs product. Plasticizers, household building materials, and cosmetics and personal care products were likely PAE sources in indoor dusts. The risk assessment suggested that carcinogenic risks of BBzP and DEHP were negligible, but DBP, DEHP, DnOP and BBzP may pose non-cancer risks to humans.


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