scholarly journals Gastric parietal cell and thyroid autoantibodies in recurrent aphthous stomatitis patients with concomitant oral lichen planus

2018 ◽  
Vol 117 (11) ◽  
pp. 987-993 ◽  
Author(s):  
Yang-Che Wu ◽  
Julia Yu-Fong Chang ◽  
Yi-Ping Wang ◽  
Yu-Hsueh Wu ◽  
Hsin-Ming Chen ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Parietal Cell ◽  
Oral Lichen Planus ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Thyroid Autoantibodies ◽  
Gastric Parietal Cell ◽  
Oral Lichen

scholarly journals Topical NAVS naphthalan for the treatment of oral lichen planus and recurrent aphthous stomatitis: A double blind, randomized, parallel group study

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0249862
Author(s):  
Ana Andabak Rogulj ◽  
Iva Z. Alajbeg ◽  
Vlaho Brailo ◽  
Ivana Škrinjar ◽  
Ivona Žužul ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Secondary Outcome ◽  
Double Blind ◽  
Link Type ◽  
Lesion Diameter ◽  
Group A ◽  
Oral Lichen

Aim To evaluate the effectiveness of non-aromatic very rich in steranes (NAVS) naphthalan in the treatment of oral lichen planus (OLP) and recurrent aphthous stomatitis (RAS). Null hypothesis was that there would be no difference between NAVS and topical steroids in the treatment of OLP and RAS. Methods The study consisted of two sub-trials conducted as randomized, double-blind controlled studies: first included OLP patients and second patients with RAS. Patients received either NAVS or 0.05% betamethasone dipropionate. Primary outcomes were activity score (OLP patients), No of lesions and lesion diameter (RAS patients) and pain intensity (VAS) while secondary outcome included the impact of the disease on quality of life assessed by Oral health impact profile (OHIP 14). Results No significant differences in terms of OLP clinical signs (p = 0.84, η2 = 0.001) and responses on the OHIP-14 (p = 0.81, η2 = 0.002) or on VAS (p = 0.14, η2 = 0.079) between NAVS and betamethasone groups were observed. In RAS patients, no significant differences between the groups in terms of lesion number (at days 3 and 5, p = 0.33 and p = 0.98, respectively), lesion diameter (days 3 and 5, p = 0.24 and p = 0.84, respectively) were observed. However, in NAVS group a significant reduction of lesions diameter was observed on the 3rd day, while in betamethasone group a significant reduction in lesions diameter was evident only after the 5th day. No significant differences in VAS (p > 0.05) and the OHIP-14 (p > 0.05) between groups were found. Conclusion No evidence of differences between the two compared interventions was found. Registration Retrospective registration of this trial was conducted in ClinicalTrials.gov on September 30, 2016; trial registration number: NCT02920658. https://clinicaltrials.gov/ct2/show/NCT02920658?term=NAVS&draw=2&rank=4.

scholarly journals Role of Zinc in Improvement, Prevention, and Treatment of the Noncommunicable Oral Diseases: Review of Literature

2021 ◽  
Vol 10 ◽  
pp. 2071
Author(s):  
Farzaneh Agha-Hosseini ◽  
Mahdieh-Sadat Moosavi ◽  
Sanam Talaei
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Burning Mouth Syndrome ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Oral Lesions ◽  
Oral Diseases ◽  
Burning Mouth ◽  
Oral Lichen

Zinc, as the second most abundant trace element present in the living organisms after iron, plays a key role in the structural, catalytic, and signaling felds. Beyond the numerous systemic symptoms of zinc defciency, it may also contribute to different processes of oral diseases. The articles were collected from three search engines including PUBMED, GOOGLE SCHOLAR, and SCOPUS. The search keywords are as follows: Zinc, trace elements, zinc defciency, oral diseases, oral lesions, recurrent aphthous stomatitis, oral lichen planus, oral squamous cell carcinoma, burning mouth syndrome, xerostomia, neuropathy. Many diverse articles including original article, case report/case series, and review articles were collected. Several studies have investigated the role of zinc and its defciency in the development of various types of noncommunicable oral lesions including recurrent aphthous stomatitis (RAS), oral lichen planus (OLP), precancerous lesions of the oral cavity (leukoplakia and submucosal fbrosis), oral cancer, xerostomia and burning mouth syndrome, periodontal disease, and Caries. Therefore, the present research was conducted to review the previous studies performed in this feld. [GMJ.2021;10:e2071]

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