Binuclear Ni(II) complexes containing ONS donor Schiff base ligands: Preparation, spectral characterization, X-ray crystallography and biological exploration

2,4,6-Triphenylbenzaldehyde 1 undergoes a condensation reaction with 2-aminophenol to give N-(2′,4′,6′-triphenylbenzylidene)-2-iminophenol (TPIP) 2. The imine 2 can be reduced with NaBH4 in ethanol to form N-(2′,4′,6′-triphenylbenzyl)-2-aminophenol (TPAP) 3. Addition of trimethylaluminum to 2 or 3 results in the formation of the complexes TPIP-AlMe2·AlMe3 (4) or TPAP-AlMe2 (5). Compounds 2, 3, and 4 have been crystallographically characterized.Key words: N,O ligands, aluminum, m-terphenyl, Schiff bases, X-ray crystallography.

Download Full-text

Structure and spectroscopy of uranyl salicylaldiminate complexes

Radiochimica Acta ◽

10.1524/ract.2013.2071 ◽

2013 ◽

Vol 101 (10) ◽

pp. 631-636 ◽

Cited By ~ 1

Author(s):

A. L. Tamasi ◽

C. L. Barnes ◽

J. R. Walensky

Keyword(s):

Schiff Base ◽

Nmr Spectroscopy ◽

Coordination Sphere ◽

Ancillary Ligand ◽

Schiff Base Ligands ◽

Uranyl Complexes ◽

X Ray ◽

X Ray Crystallography ◽

Chloride Ligand ◽

C Nmr

Summary The synthesis of uranyl complexes coordinated to tridentate, monoanionic salicylaldiminate (Schiff base) ligands was achieved by the reaction of UO2Cl2(THF)3, 1, with one equivalent of the corresponding sodium salicylaldiminate salts affording [(C9H6N)N=C(H)C6H2t Bu2O]UO2Cl(THF), 2, [(NC5H4)N=C(H)C6H2 t Bu2O]UO2Cl(THF), 3, and [(C6H4SCH3)N=C(H)C6H2tBu2O]UO2Cl(THF), 4. These are uncommon examples of uranyl complexes with a monoanionic ancillary ligand to stabilize the coordination sphere and one chloride ligand. Compounds 2-4 have been characterized by 1H and 13C NMR spectroscopy as well as IR and UVVis spectroscopy and their structures determined by X-ray crystallography.

Download Full-text

A series of trinuclear zinc(ii) complexes with reduced Schiff base ligands: turn-off fluorescent chemosensors with high selectivity for nitroaromatics

New Journal of Chemistry ◽

10.1039/c9nj02060h ◽

2019 ◽

Vol 43 (25) ◽

pp. 10093-10102 ◽

Cited By ~ 13

Author(s):

Mainak Karmakar ◽

Sourav Roy ◽

Shouvik Chattopadhyay

Keyword(s):

Schiff Base ◽

High Selectivity ◽

Fluorescent Chemosensors ◽

Schiff Base Ligands ◽

X Ray ◽

X Ray Crystallography ◽

Reduced Schiff Base ◽

Reduced Schiff Base Ligands

A series of trinuclear zinc(ii) complexes have been synthesized and characterized by X-ray crystallography. The ability of the complexes to act as sensors for the detection of nitroaromatics in DMF has been assessed.

Download Full-text

Molybdenum(VI) complexes with tridentate Schiff base ligands derived from isoniazid as catalysts for the oxidation of sulfides: synthesis, X-ray crystal structure determination and spectral characterization

Journal of the Iranian Chemical Society ◽

10.1007/s13738-021-02355-0 ◽

2021 ◽

Author(s):

Hadi Kargar

Keyword(s):

Crystal Structure ◽

Schiff Base ◽

Structure Determination ◽

Spectral Characterization ◽

Crystal Structure Determination ◽

Schiff Base Ligands ◽

X Ray ◽

Oxidation Of Sulfides ◽

Tridentate Schiff Base

Download Full-text

Rhenium and technetium complexes from pentadentate (N3O2) and tetradentate (N2O2) Schiff base ligands

Canadian Journal of Chemistry ◽

10.1139/v95-281 ◽

1995 ◽

Vol 73 (12) ◽

pp. 2272-2281 ◽

Cited By ~ 16

Author(s):

Hongyan Luo ◽

Shuang Liu ◽

Steven J. Rettig ◽

Chris Orvig

Keyword(s):

Schiff Base ◽

Least Squares ◽

Oxygen Transfer ◽

Schiff Base Ligands ◽

Full Matrix ◽

Space Group ◽

X Ray ◽

X Ray Crystallography ◽

Rhenium Complex

The rhenium(V) and technetium(V) complexes: [ReO(apa)], [{ReO(epa)}2O], and [TcOCl(epa)] have been prepared from a potentially pentadentate N3O2 ligand, N,N′-3-azapentane-1,5-diylbis(3-(1-iminoethyl)-6-methyl-2H-pyran-2,4(3H)-dione) (H3apa), or a potentially tetradentate N2O2 ligand, N,N′-ethylene-diylbis(3-(1-iminoethyl)-6-methyl-2H-pyran-2,4(3H)-dione) (H2epa). The N2O2 complexes were synthesized in low yields. There was also evidence indicating that H2ppa, N,N′-propylene-diylbis(3-(1-iminoethyl)-6-methyl-2H-pyran-2,4(3H)-dione), hydrolyzed in the course of coordination, forms a rhenium complex of the bidentate monoprotic (O,O) dehydroacetate (dha−), [Re(dha)Cl2(OPPh3)(PPh3)]•EtOH. The structure of this complex was determined by X-ray crystallography. Crystals of [Re(dha)Cl2(OPPh3)(PPh3)] EtOH (C44H37Cl2O5P2Re•C2H6O) are monoclinic, a = 11.064(2), b = 24.167(2), c = 16.6687(8) Å, β = 98.779(7)°, Z = 4, space group P21/c. The structure was solved by the Patterson method and refined by full-matrix least-squares procedures to R = 0.030 and Rw = 0.025 for 6942 reflections with I ≥ 3σ(F2). Keywords: dehydroacetic acetate based Schiff base ligands, rhenium, technetium, N3O2 Schiff base, N2O2 Schiff base, oxygen transfer.

Download Full-text

Tetranuclear Copper and Mononuclear Nickel Complex of the Schiff Base of (3Z)-3-Hydrazonobutan-2-One Oxime with Different Aromatic Carbonyl Compounds: Synthesis, Single Crystal X-Ray Structure, Catecholase Activity, Phenoxazinone Synthase Activity, Catalytic Study for the Homocoupling of Benzyl Amines

10.26434/chemrxiv.9632036.v1 ◽

2019 ◽

Author(s):

Swaraj Sengupta ◽

Sahanwaj Khan ◽

Shyamal K. Chattopadhyay ◽

Indrani Banerjee ◽

Tarun K. Panda ◽

...

Keyword(s):

Schiff Base ◽

Single Crystal ◽

Copper Complex ◽

Carbonyl Compounds ◽

Nickel Complex ◽

Schiff Base Ligands ◽

X Ray ◽

Phenoxazinone Synthase ◽

Catecholase Activity ◽

Aromatic Carbonyl Compounds

Synthesis and characterisation of one trinuclear copper complex, ([Cu3L3O]ClO4) (1) and one nickel complex ([Ni(L'H)2(dmso)2](ClO4)2) (2) with Schiff base ligands: (3Z)-3-((Z)-(1-(thiophen-2-yl)ethylidene)hydrazono)butan-2-one oxime (LH) and 1-(pyridin-2-yl)ethylidene)hydrazono)butan-2-one oxime (L'H). 1 shows high catecholase activity and has also been tested as a catalyst for the synthesis of benzylimine. 2 shows phenoxazinone synthase activity.

Download Full-text

New Copper Compounds with Antiplatelet Aggregation Activity

Medicinal Chemistry ◽

10.2174/1573406415666190222123207 ◽

2019 ◽

Vol 15 (8) ◽

pp. 850-862

Author(s):

Mirthala Flores-García ◽

Juan Manuel Fernández-G. ◽

Cristina Busqueta-Griera ◽

Elizabeth Gómez ◽

Simón Hernández-Ortega ◽

...

Keyword(s):

Schiff Base ◽

Solid State ◽

Thrombotic Event ◽

X Ray Diffraction ◽

Nmr Studies ◽

Schiff Base Ligands ◽

X Ray ◽

Antiplatelet Aggregation ◽

Aggregation Activity ◽

L1 And L2

Background: Ischemic heart disease, cerebrovascular accident, and venous thromboembolism have the presence of a thrombotic event in common and represent the most common causes of death within the population. Objective: Since Schiff base copper(II) complexes are able to interact with polyphosphates (PolyP), a procoagulant and potentially prothrombotic platelet agent, we investigated the antiplatelet aggregating properties of two novel tridentate Schiff base ligands and their corresponding copper( II) complexes. Methods: The Schiff base ligands (L1) and (L2), as well as their corresponding copper(II) complexes (C1) and (C2), were synthesized and characterized by chemical analysis, X-ray diffraction, mass spectrometry, and UV-Visible, IR and far IR spectroscopy. In addition, EPR studies were carried out for (C1) and (C2), while (L1) and (L2) were further analyzed by 1H and 13C NMR. Tests for antiplatelet aggregation activities of all of the four compounds were conducted. Results: X-ray diffraction studies show that (L1) and (L2) exist in the enol-imine tautomeric form with a strong intramolecular hydrogen bond. NMR studies show that both ligands are found as enol-imine tautomers in CDCl3 solution. In the solid state, the geometry around the copper(II) ion in both (C1) and (C2) is square planar. EPR spectra suggest that the geometry of the complexes is similar to that observed in the solid state by X-ray crystallography. Compound (C2) exhibited the strongest antiplatelet aggregation activity. Conclusion: Schiff base copper(II) complexes, which are attracting increasing interest, could represent a new approach to treat thrombosis by blocking the activity of PolyP with a potential anticoagulant activity and, most importantly, demonstrating no adverse bleeding events.

Download Full-text