scholarly journals Role of echocardiography for catheter-based management of valvular heart disease

2017 ◽  
Vol 69 (1) ◽  
pp. 66-73 ◽  
Author(s):  
Takahiro Shiota
Keyword(s):  
Heart Disease ◽  
Valvular Heart Disease

scholarly journals The Emerging Role of Exercise Testing and Stress Echocardiography in Valvular Heart Disease

2009 ◽  
Vol 54 (24) ◽  
pp. 2251-2260 ◽  
Author(s):  
Eugenio Picano ◽  
Philippe Pibarot ◽  
Patrizio Lancellotti ◽  
Jean Luc Monin ◽  
Robert O. Bonow
Keyword(s):  
Heart Disease ◽  
Exercise Testing ◽  
Valvular Heart Disease ◽  
Stress Echocardiography

scholarly journals Role of Serotoninergic Pathways in Drug-Induced Valvular Heart Disease and Diagnostic Features by Echocardiography

2009 ◽  
Vol 22 (8) ◽  
pp. 883-889 ◽  
Author(s):  
Sakima A. Smith ◽  
Alan D. Waggoner ◽  
Lisa de las Fuentes ◽  
Victor G. Davila-Roman
Keyword(s):  
Heart Disease ◽  
Valvular Heart Disease ◽  
Drug Induced ◽  
Diagnostic Features

Comparative Effects of Platelet Suppressant Drugs on Platelet Survival Time

1975 ◽  
Author(s):  
E. Genton ◽  
J. Ellis ◽  
P. Steele
Keyword(s):  
Heart Disease ◽  
Venous Thromboembolism ◽  
Valvular Heart Disease ◽  
Laboratory Tests ◽  
Drug Effect ◽  
Platelet Reactivity ◽  
In Vitro Tests ◽  
Platelet Survival

The important role of platelets in thrombosis makes inhibitors of their reactivity potentially useful therapeutically. A number of laboratory tests have been identified which measure platelet reactivity, but it is not clear which test and which drug effect will correlate with thrombosis and thrombosis prevention. Platelet survival (SURV) correlates with thromboembolism in patients with valvular heart disease and is shortened in several other diseases. Therefore, it is of interest to identify drugs which prolong shortened SURV. Patients with arterial and venous thromboembolism and shortened SURV (51Chromium) were treated with platelet suppressants and restudied after 12 weeks. Sulfinpyrazone prolonged SURV(2.4±.04 to 3.1 ±.06 days; p < 0.001; n = 94; average ± SEM; normal, 3.7±.04 days) and 68 (72%) had some prolongation and 39 (42%) had normalization (> 3.3 days). Dipyridamole (100 mg qd) combined with aspirin (1200 mg qd) prolonged SURV (2.6±.11 to 3.2±0.12 days; p < 0.001; n = 13) and 9 of 13 (69%) had prolongation and 6 (46%) had normalization. Clofibrate altered SURV (2.6±.09 to 3.4±.14days;p < 0.001; n = 12) and 10 of 12 (83% ) had prolongation and normalization occurred in 6 (50%). Aspirin (1200 mg qd), cyproheptadine (32 mg qd) and propranolol (160 mg qd) failed to alter SURV.Thus, of drugs which alter in vitro tests of platelet reactivity, only sulfinpyrazone, dipyridamole and clofibrate improve shortened SURV.

scholarly journals Clinical Applications of Natriuretic Peptides in Assessment of Valvular Heart Disease

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Abhishek Sharma ◽  
Vaseem Ahmed ◽  
Aakash Garg ◽  
Chirag Aggarwal
Keyword(s):  
Heart Disease ◽  
Natriuretic Peptides ◽  
Valvular Heart Disease ◽  
Clinical Utility ◽  
Surgical Intervention ◽  
Clinical Applications ◽  
Asymptomatic Patients ◽  
Routine Surveillance ◽  
Valvular Lesions

Biomarkers such as natriuretic peptides (NPs) have evolving clinical utility beyond the scope of heart failure. The role of NPs in the management of valvular heart disease is a growing area of investigation. NPs have much potential in the assessment of asymptomatic patients with hemodynamically significant valvular lesions who have traditionally been excluded from consideration of surgical intervention. NPs also have a role in the risk stratification of these patients as well as in routine surveillance and monitoring. Together with echocardiographic data and functional status, NPs are being incorporated into the management of valvular heart disease. In this review we examine the evidence for the role of natriuretic peptides in assessment of VHD.

scholarly journals “A Tale of Two Cities”: Anticoagulation Management in Patients with Atrial Fibrillation and Prosthetic Valves in the Era of Direct Oral Anticoagulants

Medicina ◽  
2019 ◽  
Vol 55 (8) ◽  
pp. 437
Author(s):  
Giuseppe Palmiero ◽  
Enrico Melillo ◽  
Antonino Salvatore Rubino
Keyword(s):  
Atrial Fibrillation ◽  
Heart Disease ◽  
Valvular Heart Disease ◽  
Therapeutic Option ◽  
Vitamin K Antagonists ◽  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Anticoagulation Management ◽  
Prosthetic Valves

Valvular heart disease and atrial fibrillation often coexist. Oral vitamin K antagonists have represented the main anticoagulation management for antithrombotic prevention in this setting for decades. Novel direct oral anticoagulants (DOACs) are a new class of drugs and currently, due to their well-established efficacy and security, they represent the main therapeutic option in non-valvular atrial fibrillation. Some new evidences are exploring the role of DOACs in patients with valvular atrial fibrillation (mechanical and biological prosthetic valves). In this review we explore the data available in the medical literature to establish the actual role of DOACs in patients with valvular heart disease and atrial fibrillation.

scholarly journals Cardiovascular magnetic resonance imaging in valvular heart disease

2016 ◽  
Vol 20 (2) ◽  
Author(s):  
Miranda Durand
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Heart Disease ◽  
Magnetic Resonance ◽  
Valvular Heart Disease ◽  
Pulse Sequences ◽  
Optimal Time ◽  
Resonance Imaging ◽  
Excellent Tool

The superb spatial and temporal resolution of cardiovascular magnetic resonance (CMR), as well as its reproducibility and independence from patient body habitus and acoustic window, make it an excellent tool for not only diagnostic assessment but also follow-up of valvular heart disease (VHD) patients to determine the optimal time for intervention. This article reviews the anatomy and pulse sequences used to assess these patients and provides an approach for CMR valvular assessment. In addition, it reviews the role of CMR in the assessment of patients with VHD.

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