A combined spectroscopic and molecular docking study on site selective binding interaction of Toluidine blue O with Human and Bovine serum albumins

2014 ◽  
Vol 151 ◽  
pp. 206-218 ◽  
Author(s):  
Arumugam Selva Sharma ◽  
Shanmugam Anandakumar ◽  
Malaichamy Ilanchelian
Keyword(s):  
Molecular Docking ◽  
Toluidine Blue ◽  
Bovine Serum ◽  
Docking Study ◽  
Serum Albumins ◽  
Molecular Docking Study ◽  
Binding Interaction ◽  
Selective Binding ◽  
Site Selective

Exploring the thermodynamics and conformational aspects of nicotinic acid binding with bovine serum albumin: a detailed calorimetric, spectroscopic and molecular docking study

RSC Advances ◽  
2016 ◽  
Vol 6 (41) ◽  
pp. 34754-34769 ◽  
Author(s):  
Tarlok Singh Banipal ◽  
Amandeep Kaur ◽  
Imran Ahmd Khan ◽  
Parampaul Kaur Banipal
Keyword(s):  
Molecular Docking ◽  
Light Scattering ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Docking Study ◽  
Vitamin B ◽  
Spectroscopic Techniques ◽  
Molecular Docking Study ◽  
Binding Interaction

An attempt to obtain a physicochemical and conformational outlook on the binding interaction of vitamin B3 (NA) with a model transport protein BSA using calorimetry, light scattering, molecular docking, and spectroscopic techniques.

Probing the binding interaction of zinc (II) Schiff bases with bovine serum albumin: A spectroscopic and molecular docking study

2021 ◽  
Author(s):  
Megha Sen Chowdhury ◽  
Anwita Sarkar ◽  
Sristi Raj Rai ◽  
Sanchari Dasgupta ◽  
Ishani Majumder ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Schiff Bases ◽  
Bovine Serum ◽  
Docking Study ◽  
Molecular Docking Study ◽  
Binding Interaction

scholarly journals Synthesis, Cyclooxygenases Inhibition Activities and Interactions with BSA of N-substituted 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones Derivatives

Molecules ◽  
2020 ◽  
Vol 25 (12) ◽  
pp. 2934 ◽  
Author(s):  
Edward Krzyżak ◽  
Dominika Szkatuła ◽  
Benita Wiatrak ◽  
Tomasz Gębarowski ◽  
Aleksandra Marciniak
Keyword(s):  
Molecular Docking ◽  
Docking Study ◽  
Serum Albumins ◽  
Molecular Docking Study ◽  
Binding Interaction ◽  
Ic50 Value ◽  
Cox 2 ◽  
Therapeutic Activities ◽  
Cox 1

Inhibition of cyclooxygenase is the way of therapeutic activities for anti-inflammatory pharmaceuticals. Serum albumins are the major soluble protein able to bind and transport a variety of exogenous and endogenous ligands, including hydrophobic pharmaceuticals. In this study, a novel N-substituted 1H-pyrrolo[3–c]pyridine-1,3(2H)-diones derivatives were synthesized and biologically evaluated for their inhibitory activity against cyclooxygenases and interactions with BSA. In vitro, COX-1 and COX-2 inhibition assays were performed. Interaction with BSA was studied by fluorescence spectroscopy and circular dichroism measurement. The molecular docking study was conducted to understand the binding interaction of compounds in the active site of cyclooxygenases and BSA. The result of the COX-1 and COX-2 inhibitory studies revealed that all the compounds potentially inhibited COX-1 and COX-2. The IC50 value was found similar to meloxicam. The intrinsic fluorescence of BSA was quenched by tested compounds due to the formation of A/E–BSA complex. The results of the experiment and molecular docking confirmed the main interaction forces between studied compounds and BSA were hydrogen bonding and van der Waals force.

Binding interaction, conformational change, and molecular docking study of N-(pyridin-2-ylmethylene)aniline derivatives and carbazole Ru(II) complexes with human serum albumins

Polyhedron ◽  
2016 ◽  
Vol 107 ◽  
pp. 124-135 ◽  
Author(s):  
Saravanan Thangavel ◽  
Ramar Rajamanikandan ◽  
Holger B. Friedrich ◽  
Malaichamy Ilanchelian ◽  
Bernard Omondi
Keyword(s):  
Molecular Docking ◽  
Human Serum ◽  
Conformational Change ◽  
Docking Study ◽  
Serum Albumins ◽  
Molecular Docking Study ◽  
Binding Interaction ◽  
Aniline Derivatives

Binding interaction of an anionic amino acid surfactant with bovine serum albumin: physicochemical and spectroscopic investigations combined with molecular docking study

RSC Advances ◽  
2015 ◽  
Vol 5 (96) ◽  
pp. 79107-79118 ◽  
Author(s):  
Somnath Dasmandal ◽  
Arjama Kundu ◽  
Suparna Rudra ◽  
Ambikesh Mahapatra
Keyword(s):  
Molecular Docking ◽  
Amino Acid ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Docking Study ◽  
Molecular Docking Study ◽  
Binding Interaction ◽  
Spectroscopic Investigations

Exploration of binding interaction between anionic amino acid surfactant and BSA.

Molecular interaction of cationic gemini surfactant with bovine serum albumin: A spectroscopic and molecular docking study

2014 ◽  
Vol 49 (4) ◽  
pp. 623-630 ◽  
Author(s):  
Muzaffar Ul Hassan Mir ◽  
Jitendra Kumar Maurya ◽  
Shahnawaz Ali ◽  
Shah Ubaid-ullah ◽  
Abbul Bashar Khan ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Molecular Interaction ◽  
Bovine Serum ◽  
Gemini Surfactant ◽  
Docking Study ◽  
Molecular Docking Study ◽  
Cationic Gemini Surfactant
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