Characterization of three-dimensional anisotropic heart valve tissue mechanical properties using inverse finite element analysis

2016 ◽  
Vol 62 ◽  
pp. 33-44 ◽  
Author(s):  
Mostafa Abbasi ◽  
Mohammed S. Barakat ◽  
Koohyar Vahidkhah ◽  
Ali N. Azadani
Keyword(s):  
Mechanical Properties ◽  
Finite Element Analysis ◽  
Finite Element ◽  
Heart Valve ◽  
Three Dimensional ◽  
Element Analysis ◽  
Valve Tissue ◽  
Heart Valve Tissue ◽  
Inverse Finite Element Analysis

Three-Dimensional High Resolution Scaffold Fiber Architecture and Morphology in Tissue Engineered Heart Valve Tissue

2010 ◽  
Author(s):  
Chad E. Eckert ◽  
Brandon T. Mikulis ◽  
Dane Gerneke ◽  
Danielle Gottlieb ◽  
Bruce Smaill ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
High Resolution ◽  
Heart Valve ◽  
Structural Information ◽  
Three Dimensional ◽  
Tissue Scaffold ◽  
Valve Tissue ◽  
Sampling Protocols ◽  
Heart Valve Tissue

Engineered heart valve tissue (EHVT) has received much attention as a potential pediatric valve replacement therapy, offering prospective long-term functional improvements over current options. A significant gap in the literature exists, however, regarding estimating tissue mechanical properties from tissue-scaffold composites. Detailed three-dimensional structural information prior to implantation (in vitro) and after implantation in (in vivo) is needed for improved modeling of tissue properties. As such, a novel high-resolution imaging technique will be employed to obtain three-dimensional microstructural information. Analysis techniques will be used to fully quantify constituents of interest including scaffold, collagen, and cellular information and to develop appropriate two-dimensional sectioning sampling protocols. It is the intent of this work to guide modeling efforts to better elucidate EHVT tissue-specific mechanical properties.

Influence of Different Shapes to the Dynamic Mechanical Properties of Bioprosthetic Heart Valve

2012 ◽  
Vol 500 ◽  
pp. 417-422
Author(s):  
Xu Huang ◽  
Quan Yuan ◽  
Cheng Rui Zhang ◽  
Hai Bo Ma ◽  
Xin Ye
Keyword(s):  
Mechanical Properties ◽  
Finite Element Analysis ◽  
Finite Element ◽  
Heart Valve ◽  
Dynamic Mechanical Properties ◽  
Bioprosthetic Heart Valve ◽  
Element Analysis ◽  
Geometrical Features ◽  
The Finite Element Analysis ◽  
Different Shapes

The stress with different shapes of the same thickness of the leaflet under the same load is analysed and compared by us. We create the spherical and ellipsoidal curved surface in accordance with geometrical features. The experimental results of the finite element analysis show that stress distribution of the different bioprosthetic heart valve leaflets with the same thickness is different. This work is very helpful to manufacture reasonable shaped valvular leaflets and to prolong the lifetime of the bioprosthetic heart valve.

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