Parenterally Administered Moderate Sedation and Paracervical Block Versus General Anesthesia for Hysteroscopic Polypectomy: A Pilot Study Comparing Postoperative Outcomes

2015 ◽  
Vol 22 (2) ◽  
pp. 193-198 ◽  
Author(s):  
Gabriele Centini ◽  
Andrea Calonaci ◽  
Lucia Lazzeri ◽  
Claudia Tosti ◽  
Caterina Palomba ◽  
...  
Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Jae Yen Song ◽  
Hoon Choi ◽  
Minsuk Chae ◽  
Jemin Ko ◽  
Young Eun Moon

Abstract Background Because of the indiscriminate use of opioids during the perioperative period, opioid-free anesthesia (OFA) has been increasingly required. Nevertheless, the studies on the detailed techniques and effects of OFA are not sufficient. The Quality of Recovery-40 (QoR-40) questionnaire is a validated assessment tool for measuring recovery from general anesthesia. However, no study has used the QoR-40 to determine if OFA leads to better recovery than standard general anesthesia. Therefore, we aim to perform this study to determine the effects of OFA using dexmedetomidine and lidocaine on the quality of recovery as well as the various postoperative outcomes. Methods The participants (n = 78) will be allocated to one of the two groups; the study group will receive bolus and infusion of dexmedetomidine and lidocaine, and the control group will receive remifentanil infusion during general anesthesia for gynecological laparoscopy. The other processes including anesthetic and postoperative care will be performed similarly in the two groups. Intraoperative hemodynamic, anesthetic, and nociceptive variables will be recorded. Postoperative outcomes such as QoR-40, pain severity, and opioid-related side effects will be assessed. Additionally, an ancillary cytokine study (inflammatory cytokine, stress hormone, and reactive oxygen species) will be performed during the study period. Discussion This will be the first study to determine the effect of OFA, using the combination of dexmedetomidine and lidocaine, on the quality of recovery after gynecological laparoscopy compared with standard general anesthesia using remifentanil. The findings from this study will provide scientific and clinical evidence on the efficacy of OFA. Trial registration ClinicalTrials.gov NCT04409964. Registered on 28 May 2020


1981 ◽  
Vol 54 (4) ◽  
pp. 310-313 ◽  
Author(s):  
Randall C. Cork ◽  
Robert W. Vaughan ◽  
John B. Bentley

Author(s):  
Leslie B. Scorza

Interventional radiology (IR) is a specialty often called on to help solve many different clinical problems. Sometimes, that help comes by obtaining a diagnosis, other times by treatment, and still other times by both. The array of problems for which an IR consultation can be helpful is quite broad. Some IR procedures, which are described in more detail in this chapter, include, Abscess drainage, Arterial procedures and interventions, Biliary procedures and interventions, Gastrointestinal procedures and interventions, Genitourinary procedures and interventions, Intraoperative cases, Noninvasive vascular imaging, Percutaneous oncologic interventions, Percutaneous biopsies, Venous procedures and interventions, Venous access. The anesthesia needed to accomplish these procedures, just like the procedures themselves, varies widely. Anesthesia support can range from none at all up to and including general anesthesia. However, the majority of these procedures can be successfully accomplished with the use of “sedation and analgesia,” also known as moderate sedation.


2020 ◽  
Vol 35 (11) ◽  
pp. 3138-3144
Author(s):  
Mohanad Baldawi ◽  
George McKelvey ◽  
Wael Saasouh ◽  
Sameul Perov ◽  
Gamal Mostafa ◽  
...  

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