Evolution and long term outcome in patients presenting with large demyelinating lesions as their first clinical event

2010 ◽  
Vol 297 (1-2) ◽  
pp. 29-35 ◽  
Author(s):  
Pandurang R. Wattamwar ◽  
Neeraj N. Baheti ◽  
Chandrasekharan Kesavadas ◽  
Muralidharan Nair ◽  
Ashalatha Radhakrishnan
2016 ◽  
Vol 37 (7) ◽  
pp. 1113-1117 ◽  
Author(s):  
Rocco Totaro ◽  
C. Di Carmine ◽  
A. Splendiani ◽  
S. Torlone ◽  
L. Patriarca ◽  
...  

Blood ◽  
2010 ◽  
Vol 116 (12) ◽  
pp. 2040-2045 ◽  
Author(s):  
Bertrand Coiffier ◽  
Catherine Thieblemont ◽  
Eric Van Den Neste ◽  
Gérard Lepeu ◽  
Isabelle Plantier ◽  
...  

Abstract We report the outcome of patients included in the LNH-98.5 study, which compared cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) to rituximab plus CHOP (R-CHOP) therapy in 399 patients with diffuse large B-cell lymphoma (DLBCL) aged 60 to 80 years, with a median follow-up time of 10 years. Clinical event information was updated in all living patients (with the exception of 3 patients) in 2009. Survival end points were improved in patients treated with R-CHOP: the 10-year progression-free survival was 36.5%, compared with 20% with CHOP alone, and the 10-year overall survival was 43.5% compared with 27.6%. The same risk of death due to other diseases, secondary cancers, and late relapses was observed in both study arms. Relapses occurring after 5 years represented 7% of all disease progressions. The results from the 10-year analysis confirm the benefits and tolerability of the addition of rituximab to CHOP. Our findings underscore the need to treat elderly patients as young patients, with the use of curative chemotherapy.


2001 ◽  
Vol 120 (5) ◽  
pp. A624-A624 ◽  
Author(s):  
J ARTS ◽  
M ZEEGERS ◽  
G DHAENS ◽  
G VANASSCHE ◽  
M HIELE ◽  
...  

2006 ◽  
Vol 175 (4S) ◽  
pp. 490-490
Author(s):  
Stefan Zastrow ◽  
Sven Oehlschläger ◽  
Oliver W. Hakenberg ◽  
Steffen Leike ◽  
Manfred P. Wirth

2006 ◽  
Vol 175 (4S) ◽  
pp. 420-421
Author(s):  
Gemma Viola Fantini ◽  
Andrew Nisbet ◽  
Pejman Mortarjem ◽  
Claudia Panzer ◽  
Ricardo Munarriz

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