Hypertrophic pachymeningitis: A single entity for a variety of neuroradiological findings

2021 ◽  
Vol 429 ◽  
pp. 118325
Author(s):  
Sara Iolanda Piras ◽  
Maria Tappatà ◽  
Elena Pasini ◽  
Patrizia Riguzzi ◽  
Roberto Michelucci ◽  
...  
Keyword(s):  
Hypertrophic Pachymeningitis ◽  
Single Entity

scholarly journals IgG4-related intracranial disease

2018 ◽  
Vol 32 (1) ◽  
pp. 29-35 ◽  
Author(s):  
Shahine Goulam-Houssein ◽  
Jeffrey L Grenville ◽  
Katerina Mastrocostas ◽  
David G Munoz ◽  
Amy Lin ◽  
...  
Keyword(s):  
Plasma Cells ◽  
Surgical Intervention ◽  
Case Series ◽  
Hypertrophic Pachymeningitis ◽  
Diagnostic Challenge ◽  
Perineural Spread ◽  
Related Disease ◽  
The Third ◽  
Igg4 Related Disease ◽  
Intracranial Involvement

IgG4-related disease (IgG4-RD) is a multi-organ chronic inflammatory process caused by infiltration of IgG4-positive plasma cells in one or more organs. Intracranial involvement has only recently become better recognized. Our case series adds to the growing literature on the varying presentations of intracranial IgG4 by describing the clinical and imaging findings of three patients who presented to our institution with intracranial involvement. Our first patient presented with a mass-forming IgG4 pachymeningitis mimicking a sphenoid wing meningioma, which is to our knowledge the largest mass-forming pachymeningitis published in the literature. Our second case depicts another presentation of extensive IgG4 pachymeningitis involving both cavernous sinuses and surrounding Meckel’s caves. The third case describes a patient with presumed lymphocytic hypophysitis, which was later determined to be IgG4-related hypophysitis with concomitant pachymeningitis and perineural spread along the optic nerves. The delayed diagnoses in our cases illustrates the diagnostic challenge that clinicians face in differentiating intracranial IgG4-RD from other infiltrative diseases such as sarcoidosis, granulomatous disease, tuberculosis and lymphoma. Earlier consideration of IgG4-related hypophysitis and hypertrophic pachymeningitis in the differential diagnosis can prevent significant morbidity including unnecessary surgical intervention and organ failure secondary to extensive fibrosis.

scholarly journals THE ECONOMIST AS SCIENTIST, ENGINEER, OR PLUMBER?

2021 ◽  
Vol 43 (2) ◽  
pp. 297-312
Author(s):  
Huei-Chun Su ◽  
David Colander
Keyword(s):  
Radical Change ◽  
Economic Science ◽  
Single Entity ◽  
General Contractor

Some well-known economists suggest that a good economist should act like an engineer, a surgeon, a dentist, or even a plumber. These metaphors are useful in helping economists reflect the nature of economics and their role in society. But which is the most sensible one? This paper argues that economists should be playing all these roles and more, because economics is not a single entity, and each entity has separate goals, methods, and boundaries. To take this multiplicity of roles into account, this paper argues that in addition to the traditional boundary that delineates the disciplinary domain of economics against other sciences, an overarching boundary between economic science and applied policy needs to be recognized. It then examines Esther Duflo’s “economist as plumber” metaphor and suggests that a better metaphor for Duflo’s purpose would be “general contractor,” a metaphor that, if accepted, would suggest radical change in training applied policy economists.

Size-Resolved Single Entity Collision Biosensing for Dual Quantification of MicroRNAs in a Single Run

2021 ◽  
Author(s):  
Yi-Yan Bai ◽  
Yan-Ju Yang ◽  
Zhen Wu ◽  
Xiao-Yan Yang ◽  
Miao Lin ◽  
...  
Keyword(s):  
Single Entity

scholarly journals How to talk with the family of a dying patient: anger to understanding, rage to compassion, loss to acceptance

2021 ◽  
pp. bmjspcare-2021-002971
Author(s):  
Moshe Y Flugelman
Keyword(s):  
Goal Setting ◽  
Stressful Situation ◽  
Family Needs ◽  
The Third ◽  
Single Entity ◽  
The Family ◽  
Patient Families ◽  
The Difference ◽  
Dying Patient

Informing families about the impending or actual death of their relatives is one of the most challenging and complex tasks a physician may face. The following article describes goal setting and provides five roles/recommendations for conducting the encounter with patient families regarding the imminent or actual death of their relatives. Importantly, the encounter should be family-centred, and the physician should be highly attentive to family needs. The following roles should be applied based on family needs and should not be sequential as numbered. The first and basic role is to inform the family at the earliest possible time and as often as possible. The second goal of the physician is to convey to the family that their relative received the needed therapy during his hospitalisation or in the community. The third goal of the physician is to help the family reach acceptance of the death of their relative and leave the hospital having moved beyond anger and bargaining. The fourth goal of the physician during the encounters is to reduce or alleviate guilt by stating that nothing could have changed the course of the disease and that all efforts were made to save the patient. The fifth role of the physician is to try and help the family as a single entity and maintain their unity during this stressful situation. Following these roles/methods will help families in the stressful situation and will create the difference between anger and understanding, rage and compassion, and loss and acceptance.

Idiopathic Hypertrophic Pachymeningitis Mimicking Lymphoplasmacyte-Rich Meningioma

2007 ◽  
Vol 27 (2) ◽  
pp. 95-98 ◽  
Author(s):  
Matthew R Hosler ◽  
Roger E Turbin ◽  
Eun-Sook Cho ◽  
Leo J Wolansky ◽  
Larry P Frohman
Keyword(s):  
Hypertrophic Pachymeningitis
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