Huffer’s neuropathy: A case of acute-onset tetraparesis mimicking Guillain-Barré syndrome

2021 ◽  
Vol 429 ◽  
pp. 119936
Author(s):  
Valentina Tommasini ◽  
Mauro Catalan ◽  
Lucia Antonutti ◽  
Giulia Mazzon ◽  
Marta Cheli ◽  
...  
2019 ◽  
Vol 12 (4) ◽  
pp. e228845 ◽  
Author(s):  
Sajid Hameed ◽  
Sara Khan

Chikungunya (CHIK) viral fever is a self-limiting illness that presents with severe debilitating arthralgia, myalgia, fever and rash. Neurological complications are rare. We present a case of a 36-year-old woman who presented with acute onset progressive difficulty swallowing and left arm weakness. She was diagnosed with CHIK viral fever 4 weeks prior to admission. After investigations, she was diagnosed with a pharyngeal–cervical–brachial variant of Guillain-Barré syndrome. In hospital, she required ventilator support. Her condition improved after five sessions of intravenous immunoglobulin with almost complete resolution within 6 months of symptom onset. With frequent CHIK outbreaks, the neurological complications are increasingly seen in the emergency department. The knowledge of these associations will result in early diagnosis and treatment.


2019 ◽  
Vol 10 (10.2) ◽  
pp. 98-102 ◽  
Author(s):  
Mihai Sava ◽  
Maria-Gabriela Catană ◽  
Corina Roman-Filip

Abstract Guillain-Barre syndrome (GBS) is the most common cause of acute flaccid paralysis worldwide, having an incidence of about 1/100,000 across several studies in a number of countries. We present the case of a 60-year-old female patient, with known hypertension, admitted to our department for paresthesia and muscle weakness predominantly in the distal upper and lower limbs. Symptomatology had an acute onset after 14 days from influenza vaccine administration. Lumbar puncture revealed CSF glucose (91 mg/dl), CSF protein (0.508 g/l) and no pleocytosis. Electromyography supported the presumptive diagnosis of polyradiculoneuritis. The patient underwent three sessions of double filtration and the final diagnosis was Guillain-Barre polyradiculoneuritis secondary to influenza vaccination. Approximately 80% of patients with polyradiculoneuritis recover completely within a few months to one year; however, 5-10% of these patients experience one or more recurrences. It should be emphasized that acute-phase rehabilitation must start immediately and include an individualized program of gentle strengthening, and manual resistive and progressive resistive exercises. Key words: polyradiculoneuropathy, influenza vaccine, neurorehabilitation,


2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Dhrubajyoti Bandyopadhyay ◽  
Vijayan Ganesan ◽  
Cankatika Choudhury ◽  
Suvrendu Sankar Kar ◽  
Parthasarathi Karmakar ◽  
...  

We are presenting two cases of Guillain-Barré syndrome where it is preceded by hepatitis E virus (HEV) and Japanese encephalitis virus (JEV) infection, respectively. Our first case is a forty-three-year-old nondiabetic, nonhypertensive female who was initially diagnosed with acute HEV induced viral hepatitis and subsequently developed acute onset ascending quadriparesis with lower motor neuron type of bilateral facial nerve palsies and respiratory failure. Second patient was a 14-year-old young male who presented with meningoencephalitis with acute onset symmetric flaccid paraparesis. After thorough investigations it was revealed as a case of Japanese encephalitis. Our idea of reporting these two cases is to make ourselves aware about this potential complication of these two common infections.


2017 ◽  
Vol 7 (2) ◽  
pp. 111-112
Author(s):  
NS Neki ◽  
Gagandeep Singh Shergill ◽  
Amanpreet Kaur

Guillain-Barré syndrome (GBS) is an acquired acute autoimmune polyradiculoneuropathy. Progressive motor weakness and areflexia are essential for diagnosis. But in some cases hyperreflexia can be seen. Diagnosis of GBS was made based on history and clinical findings and was supported by cerebrospinal fluid (CSF) studies and nerve conduction study (NCS). We hereby report a case of a 42-year-old male presenting with acute onset flaccid quadriparesis. There was frank hyperreflexia in all four limbs. Although reflex preservation and hyperreflexia can be noted in axonal variant of GBS in Chinese, Japanese, and European populations, it is uncommon in India.J Enam Med Col 2017; 7(2): 111-112


2010 ◽  
Vol 55 (6) ◽  
pp. 1234-1235 ◽  
Author(s):  
Ankur Bahl ◽  
Biswaroop Chakrabarty ◽  
Sheffali Gulati ◽  
K.N. Vykunta Raju ◽  
Ali Raja ◽  
...  

Author(s):  
Vinod John ◽  
Jiya Thankam Koshy ◽  
Nikhil Gladson ◽  
Vimod K. Wills

Several reports and studies are being conducted to this day based on the safety profile of COVID-19 vaccines. COVID-19 vaccination inducing GBS is a rare adverse effect and is likely to be causal. Though, there are reports concerning the relation between coronavirus infections and GBS, the pathogenic mechanism and relevant factors behind COVID-19 vaccines inducing GBS are still not being corroborated so far. Guillain-Barre syndrome is the principal cause of acute flaccid paralysis with a prevalence rate of 2 in 100, 000 people per year. We illustrate a 55 years old female patient who presented with acute onset paraesthesia and progressive weakness of bilateral lower limbs and gait imbalance of 5 days duration to the Hospital during the first week of September. Her symptoms occurred within 2 weeks of the first dose of the ChAdOx1-n-CoV-19 (Covishield) vaccine proving a major possibility of vaccine-induced neurological adverse effect as she didn't have any likely significant history of illness or allergies in the past rather than type 2 diabetes mellitus. This report aims to highlight the incidence and to ruminate upon this matter while evaluating any GBS cases in the current eras of the COVID-19 pandemic and vaccination.


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