Early mobilization reduces the medical care cost and the risk of disuse syndrome in patients with acute osteoporotic vertebral fractures

Background: Vertebral fractures are the most common type of osteoporotic fractures. These are developing into a significant health problem worldwide as about 30% of the patients above 50 years suffer from a fracture secondary to osteoporosis. Osteoporotic vertebral fractures may be treated with rest and analgesics. Some fractures may also require surgery. Percutaneous procedure like vertebroplasty and kyphoplasty done under local anaesthesia can reduce the pain and restore height of vertebral body without need for an open surgery. The aim of the study was to assess the clinical and radiological outcomes following unilateral percutaneous vertebroplasty under local anaesthesia. Methods: 21 patients who underwent unilateral vertebroplasty for symptomatic osteoporotic compression fracture between August 2019 and July 2020 were included in the study. Unilateral vertebroplasty using an 11-gauge trocar through transpedicular technique was performed under c-arm guidance. Patient was mobilized as soon as tolerated. Oswestry disability index and visual analogue scale were assessed pre-operatively, in the immediate post-op and at 1-year follow up. Results: There were 15 females and 6 males. The mean age was 70.04±6.07 years. The pre-op ODI score was 76.8±7.6. The pre-op VAS score was 7.66±0.71. The average time period from fracture to vertebroplasty is 4.19±3.19 days. The immediate post-operative VAS score was 5.76±0.8 and the ODI score was 62.85±7.17. The VAS at final follow up was 1.23±1.19. ODI at final follow up was 9.04±3.19. There was a showed a significant improvement when preoperative, immediate post-operative ODI and VAS scores and final follow up (p<0.001). Conclusions: In our study unilateral percutaneous vertebroplasty has provided pain relief, early mobilization of the patient with less complication without the requirement of general anaesthesia.

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Unilateral percutaneous vertebroplasty for symptomatic osteoporotic vertebral compression fractures -evaluation of radiological and clinical outcomes

International Journal of Research in Orthopaedics ◽

10.18203/issn.2455-4510.intjresorthop20185328 ◽

2018 ◽

Vol 5 (1) ◽

pp. 19

Author(s):

Shanmuga Sundaram Pooswamy ◽

Niranjanan Raghavn Muralidharagopalan

Keyword(s):

Vertebral Fractures ◽

Local Anaesthesia ◽

Percutaneous Vertebroplasty ◽

Compression Fracture ◽

Osteoporotic Fractures ◽

Early Mobilization ◽

Vertebral Compression Fractures ◽

Vas Score ◽

Osteoporotic Vertebral Fractures

Background: Vertebral fractures are the most common type of osteoporotic fractures. These are developing into a significant health problem worldwide as about 30% of the patients above 50 years suffer from a fracture secondary to osteoporosis. Osteoporotic vertebral fractures may be treated with rest and analgesics. Some fractures may also require surgery. Percutaneous procedure like vertebroplasty and kyphoplasty done under local anaesthesia can reduce the pain and restore height of vertebral body without need for an open surgery. The aim of the study was to assess the clinical and radiological outcomes following unilateral percutaneous vertebroplasty under local anaesthesia.Methods: 21 patients who underwent unilateral vertebroplasty for symptomatic osteoporotic compression fracture between 2012 and 2015 were included in the study. Unilateral vertebroplasty using an 11-gauge trocar through transpedicular technique was performed under c-arm guidance. Patient was mobilized as soon as tolerated. Oswestry disability index and visual analogue scale were assessed pre-operatively, in the immediate post-op and at 1-year follow up.Results: There were 15 females and 6 males. The mean age was 70.04±6.07 years. The pre-op ODI score was 76.8±7.6. The pre-op VAS score was 7.66±0.71. The average time period from fracture to vertebroplasty is 4.19±3.19 days. The immediate post-operative VAS score was 5.76±0.8 and the ODI score was 62.85±7.17. The VAS at final follow up was 1.23±1.19. ODI at final follow up was 9.04±3.19. There was a showed a significant improvement when preoperative, immediate post-operative ODI and VAS scores and final follow up (p<0.001).Conclusions: In our study unilateral percutaneous vertebroplasty has provided pain relief, early mobilization of the patient with less complication without the requirement of general anaesthesia.

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Kinesiotherapy rehabilitation program to correct deep core stability muscle dysfunction in patients with osteoporotic vertebral fractures

Endocrine Abstracts ◽

10.1530/endoabs.56.gp57 ◽

2018 ◽

Author(s):

Ekaterina Makarova ◽

Larisa Marchenkova ◽

Michail Eryomushkin

Keyword(s):

Vertebral Fractures ◽

Rehabilitation Program ◽

Core Stability ◽

Muscle Dysfunction ◽

Osteoporotic Vertebral Fractures

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The factors affecting balance function in patients with osteoporotic vertebral fractures

Endocrine Abstracts ◽

10.1530/endoabs.63.p99 ◽

2019 ◽

Author(s):

Larisa Marchenkova ◽

Ekaterina Makarova ◽

Mikhail Eryomushkin ◽

Lilia Shakurova

Keyword(s):

Vertebral Fractures ◽

Balance Function ◽

Factors Affecting ◽

Osteoporotic Vertebral Fractures

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Radiation Exposure of Anaesthetists Visualised by Real-time Dosimetry

Current Medical Imaging Formerly Current Medical Imaging Reviews ◽

10.2174/1573405613666171123151711 ◽

2019 ◽

Vol 15 (2) ◽

pp. 220-226

Author(s):

Marcus Christian Müller ◽

Michael Windemuth ◽

Sophie Frege ◽

Eva Nadine Striepens

Keyword(s):

Radiation Exposure ◽

Real Time ◽

Vertebral Fractures ◽

Plate Osteosynthesis ◽

Plate Fixation ◽

Femoral Fractures ◽

Dose Monitoring ◽

Osteoporotic Vertebral Fractures ◽

Radiation Dose Monitoring ◽

Dosimetry System

Background: Chronic exposure to occupational ionising radiation is seen as one reason for elevated cancer prevalence. Objective: The aim of this retrospective study was to evaluate radiation exposure of anaesthetists by real-time dosimetry. Methods: Data of 296 patients were analyzed. Ten types of trauma operation procedures including osteosynthesis of upper and lower extremity fractures and minimally invasive stabilisation of traumatic and osteoporotic vertebral fractures were accomplished. Evaluation was performed by an occupational dosimetry system, which visualises anaesthetists radiation exposure feedback compared to surgeons in real-time. Results: A significantly lower radiation exposure to anaesthetists compared to surgeons was observed in four types of operative procedures: Plate fixation of proximal humerus fractures, osteosynthesis of proximal femoral fractures, stabilisation of traumatic and osteoporotic vertebral fractures. In four types of operations (plate osteosynthesis of proximal humeral, distal radial and tibial fractures and intramedullary nailing of the clavicle), anaesthetists` amount of radiation exceeded one-third of the surgeons' exposure, especially if the C-arm tube was positioned close to the anaesthetists work station at the patients' head. Conclusion: By using the occupational radiation dose monitoring system, radiation exposure to anaesthetists was visualised in real-time during trauma operations. Radiation exposure of anaesthetists depends on the type of operation and the position of the C-arm. The system may help to increase anaesthetists` awareness concerning radiation exposure and to enhance compliance in using radiation protection techniques.

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Safety and efficacy of Wharton's jelly‐derived mesenchymal stem cells with teriparatide for osteoporotic vertebral fractures: A phase I/IIa study

Stem Cells Translational Medicine ◽

10.1002/sctm.20-0308 ◽

2020 ◽

Author(s):

JeongHyun Shim ◽

Kyoung‐Tae Kim ◽

Kwang Gi Kim ◽

Un‐Yong Choi ◽

Jae Won Kyung ◽

...

Keyword(s):

Stem Cells ◽

Mesenchymal Stem Cells ◽

Phase I ◽

Vertebral Fractures ◽

Wharton’S Jelly ◽

Safety And Efficacy ◽

Wharton's Jelly ◽

Osteoporotic Vertebral Fractures

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POS0016 THE EVALUATION OF FUNCTIONAL ABILITIES OF PATIENTS WITH OSTEOPOROTIC VERTEBRAL FRACTURES AS A BASIS FOR REHABILITATION PROGRAMS DEVELOPING

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2021-eular.4260 ◽

2021 ◽

Vol 80 (Suppl 1) ◽

pp. 209.2-210

Author(s):

L. Marchenkova ◽

V. Vasileva ◽

M. Eryomushkin

Keyword(s):

Muscle Strength ◽

Vertebral Fractures ◽

Trunk Muscles ◽

Control Group ◽

Study Group ◽

Primary Osteoporosis ◽

X Rays ◽

Functional Abilities ◽

Rehabilitation Programs ◽

Osteoporotic Vertebral Fractures

Background:Due to the demand for special rehabilitation programs for patients with osteoporotic vertebral fractures (VFs), it is of interest to study the functional abilities of those patients. The scientific hypothesis suggests that osteoporotic VFs would cause muscle weakness, muscle dysfunction and conditional disturbances.Objectives:to estimate muscle strength, motor function and coordination disorders in patients with VFs in the setting of systemic osteoporosis as a basis for rehabilitation programs developing.Methods:120 patients aged 43−80 with primary osteoporosis were enrolled. Study group comprised of 60 subjects (56 women, 4 men) with at least 1 VF confirmed by X-rays. Control group included 60 subjects (56 women, 4 men) with osteoporosis but without any osteoporotic fracture. The examination program included back muscles tenzodynamometry, balance tests and stabilometry.Results:Muscle strength deficiency was estimated in study group in trunk flexors (TF) — 40.9% and in trunk extensors (TE) — 18.1% with an adequate function of the left lateral flexors (LLF) and in right lateral flexors (RLF). Patients with VFs had the lower muscle strength vs controls of TE (15.64±9.8 vs 27.73±9.9 kg, p=0.00002), TF (14.61±8.98 vs 21.28±8.38 kg, p=0.0006), LLF (13.10±7.2 vs 24.06±8.9 kg, p=0.005) and RLF 13.44±7.43 vs 24.26±7.65 kg, p=0.0003). Patients with VFs lose their balance faster during one-leg-standing test with open eyes (5.0 [1.0; 10.0] vs 7.5 [5.0; 10.5] sec in control group, p=0.03) and with closed eyes (2.0 [0; 3.0] vs 3.5 [3.0; 5.0] sec, p=0.04). Fukuda-Unterberger test showed greater side dislocation in study group — 40° [25; 45] vs controls 30° [10; 45], (p=0.02). According to stabilometry study group was characterized vs control group by lower balance coefficient with open eyes (77.2±7.6 vs 85.7±9.4%, p=0.002) and with closed eyes (67.1±9.8 vs 73.4±9.9%, p=0.03), greater sagittal displacement (6.8 [2.1; 37.7] vs 4.8 [1.8; 10.7] mm, p=0.025) and deviation in the saggital plane (1.2 [-1.07; 1.5] vs -1.2 [-1.5; 1.2] mm, p=0.01), and also less pressure center velocity (9.51±4.4 vs 7.1±2.7 mm/sec, р=0.009).Conclusion:Osteoporotic VFs are associated with reduction of trunk muscles strength and negatively affect static and dynamic balance function that should be taken into account when developing rehabilitation programs for these patients.Disclosure of Interests:None declared.

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