Sclerotherapy for Vascular Malformations in the Oral and Maxillofacial Region: Treatment and Follow-Up of 66 Lesions

2011 ◽  
Vol 69 (6) ◽  
pp. e88-e92 ◽  
Author(s):  
José Ricardo Sousa Costa ◽  
Marcos Antonio Torriani ◽  
Elaini Sickert Hosni ◽  
Otávio Pereira D'Avila ◽  
Paulo Jeovane de Figueiredo
2019 ◽  
Vol 6 (4) ◽  
pp. 1356
Author(s):  
Nayana Kulkarni ◽  
Ajit Patil ◽  
Ravindra Tandale ◽  
Shital Patil ◽  
Rajnish Nagarkar

Arterio-venous malformations (AVM) are abnormal collection of blood vessels. They are rare congential vascular malformations that account for 1.5% of all vascular abnormalities while 50% of such cases occur in the oral and maxillofacial region. Facial AVM are uncommon. Patients presenting with AVMs require a complete investigation using precise clinical examination and advanced imaging modalities. The treatment of a patient with AVM includes a multi-step process. In this case, we report a case of extensive AVM in the face of a 17-year-olf female patient. The report primarily focuses on the successful anesthetic management for sclerotherapy along with insights on clinical characteristics and imaging manifestations. To the best of our knowledge, this is one of the few cases to be reported in India.


2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Yongsheng Li

Purpose: To explore the efficacy of pingyangmycin (PYM) combined with Neodymium yttrium aluminum garnet (Nd:YAG) laser to treat venous malformations in the oral and maxillofacial region. Methods: Eighty-six patients were randomly divided into two groups. Forty-two patients were allocated to the experimental group and were injected with PYM at the lesion site, followed by Nd:YAG laser irradiation two days later. Forty-four patients were allocated to the control group and received only Nd:YAG laser irradiation (15-30W of power). All patients came back for a follow-up examination one month later. Results: Twenty-eight patients in the experimental group (66.67%) and 16 patients in the control group (36.31%) had no lesions after one treatment. Additionally, 10 patients in the experimental group (23.81%) and nine patients in the control group (20.45%) showed significant improvement at one month post-treatment. Compared to the control group, the experimental group demonstrated superior outcomes and shorter treatment durations. The between-group difference was significant (p<0.05). Conclusion: PYM combined with Nd:YAG laser is an effective treatment of venous malformations in the oral and maxillofacial region, potentially shortening treatment durations.


JMS SKIMS ◽  
2013 ◽  
Vol 16 (2) ◽  
pp. 90-94 ◽  
Author(s):  
Altaf H Malik ◽  
Ajaz A Shah ◽  
Rubeena Tabasum ◽  
Irshad Ahmad ◽  
Manzoor Ahmad

Purpose: To evaluate the efficacy of PRP in regeneration of bone in defects of the oral and maxillofacial region. Methods: A comparative nonrandomized study including 40 patients with bony defects of cystic origin   in the maxillofacial region was carried out in the Department of Oral and Maxillofacial Surgery. Patients were divided into two groups: group A received PRP and in group B PRP was not used. Postoperatively, the patients were monitored regularly by radiographs to evaluate new bone growth at 1st  ,3rd and 6th month clinically and radiographically. Results: Faster bone healing in was observed in the patients in whom PRP was used at every follow up. Conclusion: Defects filled with PRP showed comparatively earlier and faster bone regeneration. JMS 2013;16(2):90-94


2008 ◽  
Vol 132 (6) ◽  
pp. 984-988 ◽  
Author(s):  
Li-Sha Sun ◽  
Zhi-Peng Sun ◽  
Xu-Chen Ma ◽  
Tie-Jun Li

Abstract Context.—Glial choristoma is an uncommon developmental abnormality typically presenting at birth or in early childhood. The nasal region is most frequently affected. Palate, tongue, cheek, scalp, and orbit can also be affected but these occurrences are relatively rare. Objective.—To report 6 cases of glial choristoma arising in the oral and maxillofacial region and to document the clinical and pathologic features of these lesions. Design.—Histologic and immunocytochemical examinations were performed on 6 cases of glial choristoma. Biologic behavior, prognosis, and pathogenesis were discussed together with a review of the literature. Result.—The patients included 5 boys and 1 girl. They all presented with the lesions at birth or soon after birth. Four lesions occurred on the dorsal side of the tongue, near the foramen caecum. One lesion was present in the infratemporal fossa and parapharyngeal space, and the other one was in the submandibular region. All patients received surgical excision, and follow-up data revealed no recurrence for a period of 10 months to 5 years after surgery. Histologically, the lesions showed mature glial cells intermixed with connective tissue. The glial tissue was strongly positive for glial fibrillary acidic protein and S100 but negative for neurofilament. Conclusion.—Glial choristoma should be classified as a developmental malformation that occurs in many sites of the head and neck. In oral cavity, the tongue is the most frequently affected site. Although these lesions are rare, they should be included in the differential diagnosis of congenital masses in the oral and maxillofacial region.


Author(s):  
Ana Carolina Velasco Pondé de Sena ◽  
José Alcides Almeida de Arruda ◽  
Fernanda Pereira Delgado Costa ◽  
Ana Paula Vilaça Lemos ◽  
Fabiana Maria Kakehasi ◽  
...  

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
K. P. Thompson ◽  
◽  
J. Nelson ◽  
H. Kim ◽  
L. Pawlikowska ◽  
...  

Abstract Background Retrospective questionnaire and healthcare administrative data suggest reduced life expectancy in untreated hereditary hemorrhagic telangiectasia (HHT). Prospective data suggests similar mortality, to the general population, in Denmark’s centre-treated HHT patients. However, clinical phenotypes vary widely in HHT, likely affecting mortality. We aimed to measure predictors of mortality among centre-treated HHT patients. HHT patients were recruited at 14 HHT centres of the Brain Vascular Malformation Consortium (BVMC) since 2010 and followed annually. Vital status, organ vascular malformations (VMs) and clinical symptoms data were collected at baseline and during follow-up (N = 1286). We tested whether organ VMs, HHT symptoms and HHT genes were associated with increased mortality using Cox regression analysis, adjusting for patient age, sex, and smoking status. Results 59 deaths occurred over average follow-up time of 3.4 years (max 8.6 years). A history of anemia was associated with increased mortality (HR = 2.93, 95% CI 1.37–6.26, p = 0.006), as were gastro-intestinal (GI) bleeding (HR = 2.63, 95% CI 1.46–4.74, p = 0.001), and symptomatic liver VMs (HR = 2.10, 95% CI 1.15–3.84, p = 0.015). Brain VMs and pulmonary arteriovenous malformations (AVMs) were not associated with mortality (p > 0.05). Patients with SMAD4 mutation had significantly higher mortality (HR = 18.36, 95% CI 5.60–60.20, p < 0.001) compared to patients with ACVRL1 or ENG mutation, but this estimate is imprecise given the rarity of SMAD4 patients (n = 33, 4 deaths). Conclusions Chronic GI bleeding, anemia and symptomatic liver VMs are associated with increased mortality in HHT patients, independent of age, and in keeping with the limited treatment options for these aspects of HHT. Conversely, mortality does not appear to be associated with pulmonary AVMs or brain VMs, for which patients are routinely screened and treated preventatively at HHT Centres. This demonstrates the need for development of new therapies to treat chronic anemia, GI bleeding, and symptomatic liver VMs in order to reduce mortality among HHT patients.


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