Is Implant Placement in the Operating Room a Risk Factor for the Development of Peri-Implantitis? A Retrospective Cohort Analysis

Abstract Aims/Introduction: Previous studies have indicated that serum alanine aminotransferase (ALT) level, serum aspartate aminotransferase (AST) level or ALT/AST ratio may be bound up with diabetes. But the association of ALT/AST ratio and incident diabetes in Chinese adults have not been elaborated yet. The main objective of the present study was to analyze whether ALT/AST ratio was an independent risk factor which attached to the risk of incident diabetes in Chinese adults.Materials and Methods From 2010 to 2016, 685,277 Chinese adults who received a health check in Rich Healthcare Group including all medical records, and the present article was a second retrospective cohort analysis based on above population. As the target independent variable, ALT/AST ratio was measured at baseline while the dependent variable, incident diabetes appeared during follow-up. We used Cox proportional hazard regression models to analyze the prognostic value of ALT/AST on the risk of incident diabetes.Results ALT/AST demonstrated undeniable correlation with incident diabetes (HR = 2.535, 95%CI: 2.190 to 2.934, P < 0.00001). The association between ALT/AST and incident diabetes is only linear. The cumulative incidence (95% CI) rate of incident diabetes in total participants, ALT/AST quartile 1, 2, 3, and 4 was 2.112 (2.016–2.208), 0.992 (.0.857–1.127), 1.430 (1.274–1.586), 2.396 (2.192-2.600) and 3.559 (3.314–3.803), separately. The population with age (30 to < 40 years), BMI (< 24 kg/m2) and SBP (< 140 mmHg) was found to be the stronger association in subgroup analysis.Conclusion In Chinese adults, ALT/AST ratio is an independent risk factor for incident diabetes.

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Assessment of Patients Referred to Specialty Dental Hospitals for Dental Implant Procedure: A Retrospective Cohort Analysis

The Journal of Contemporary Dental Practice ◽

10.5005/jp-journals-10024-1874 ◽

2016 ◽

Vol 17 (6) ◽

pp. 470-475

Author(s):

Rishi Thukral ◽

MC Prasant ◽

Krunal M Punjabi ◽

Aparna Paliwal ◽

Kunal Patel

Keyword(s):

Dental Implants ◽

Dental Implant ◽

Failure Rate ◽

Retrospective Cohort ◽

Cohort Analysis ◽

Prosthetic Rehabilitation ◽

Implant Placement ◽

Retrospective Cohort Analysis ◽

Edentulous Patients ◽

Augmentation Procedure

ABSTRACT Introduction One of the most common and effective ways of replacing missing teeth is by dental implants. Both quality and quantity of bone along with the area of implant placement govern the prognosis of the implant procedure. Certain risk factors predispose the implant treatment to high failure rate. Hence, we assessed the implant patients who were referred from private practitioners to the specialty hospitals from 2010 to 2014. Materials and methods All the patients being referred from private clinics to the specialty dental hospital for the purpose of prosthetic rehabilitation by dental implants from June 2010 to July 2014 were included in the present study. Skilled oral and maxillofacial surgeons were appointed for performing the implant surgical procedures. Prosthetic rehabilitation was done after 6 to 8 weeks and after 10 to 14 weeks in implant cases without and with bone augmentation procedures respectively. Distribution of dental implants based on the indications, location, dimension of augmentation procedure, and complication of implants was analyzed and assessed for the level of significance. Results Of the patients, 712 were females, while the remaining were males. Most of the patients were in the age group of 50 to 59 years. As compared with completely edentulous patients, most of the patients required rehabilitation by a single implant. Maximum dental implants were placed in maxillary premolar region and mandibular first molar region. Over 1,000 cases in this study required rehabilitation by augmentation procedure. Conclusion Partially edentulous patients are most commonly referred to specialized dental hospitals for prosthetic rehabilitation by dental implants, mostly with the purpose of implant placement. Failure rate can be minimized by following strict patient selection protocols along with following a standard surgical criterion. Clinical significance Following standard surgical protocols and strict treatment planning, prognosis of the dental implant procedures can be improved to a greater extent, thereby increasing its clinical success rate. How to cite this article Thukral R, Kumar A, Prasant MC, Punjabi KM, Paliwal A, Patel K. Assessment of Patients Referred to Specialty Dental Hospitals for Dental Implant Procedure: A Retrospective Cohort Analysis. J Contemp Dent Pract 2016;17(6):470-475.

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