Characterization of polysorbate 80 with liquid chromatography mass spectrometry and nuclear magnetic resonance spectroscopy: Specific determination of oxidation products of thermally oxidized polysorbate 80

2012 ◽  
Vol 62 ◽  
pp. 7-16 ◽  
Author(s):  
Erlend Hvattum ◽  
Wai Lam Yip ◽  
David Grace ◽  
Knut Dyrstad
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Liquid Chromatography ◽  
Oxidation Products ◽  
Resonance Spectroscopy ◽  
Polysorbate 80 ◽  
Liquid Chromatography Mass Spectrometry ◽  
Specific Determination

scholarly journals Effects of solasodine of Solanum melongena peel origin in the treatment of palmar arsenical keratosis

2020 ◽  
Vol 13 (2) ◽  
pp. 47-52
Author(s):  
Razia Sultana ◽  
Mir Misbahuddin
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Liquid Chromatography ◽  
Solanum Melongena ◽  
Resonance Spectroscopy ◽  
Liquid Chromatography Mass Spectrometry ◽  
Inclusion Criteria ◽  
Phone Calls ◽  
The Mean ◽  
Peel Extract

This study was conducted to confirm the effect of the ointment containing Solanum melongena peel extract in the treatment of palmar arsenical keratosis and to identify the compound responsible for the effect. In total, 30 patients with moderate to severe palmar arsenical keratosis were enrolled according to the inclusion criteria. Extract from S. melongena peel was obtained and a topical ointment was prepared from the extract and supplied at the field level at an interval of two weeks. Instruction was given to the patients about how to apply the ointment. Adherence and adverse effects of the treatment were monitored regularly through phone calls and during each visit. The mean (± SD) size of the keratotic nodules was 21.9 ± 10.0 mm2 before intervention and 6.6 ± 5.3 mm2 after intervention. The percentage of reduction was 69.8. Nuclear magnetic resonance spectroscopy, infrared spectroscopy, liquid chromatography-mass spectrometry and elemental analysis of the extract was done to identify the compound and solasodine, a steroidal alkaloid, was identified.

Liquid chromatography mass spectrometry based characterization of epitope configurations

2020 ◽  
Vol 12 (45) ◽  
pp. 5476-5484
Author(s):  
Maren Christin Stillesby Levernæs ◽  
Arelí Urtubia Moe ◽  
Sigurd Leinæs Bøe ◽  
Elisabeth Paus ◽  
Léon Reubsaet ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Three Dimensional ◽  
Dimensional Structure ◽  
Liquid Chromatography Mass Spectrometry ◽  
Three Dimensional Structure ◽  
Chromatography Mass Spectrometry ◽  
Pre Treatment

Here we evaluate a quick and easy tool for determination of epitope configuration using immunocapture and liquid chromatography mass spectrometry (LC-MS) subsequent to pre-treatment of the target protein to disrupt its three-dimensional structure.

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