UV–visible spectroscopy as an alternative to liquid chromatography for determination of everolimus in surfactant-containing dissolution media: A useful approach based on solid-phase extraction

2012 ◽  
Vol 70 ◽  
pp. 94-100 ◽  
Author(s):  
Marika Kamberi ◽  
Thu-Ngoc Tran
Keyword(s):  
Liquid Chromatography ◽  
Solid Phase Extraction ◽  
Solid Phase ◽  
Phase Extraction ◽  
Visible Spectroscopy ◽  
Uv Visible

scholarly journals Determination of 3-Trifluoromethyl-4-Nitrophenol and 3-Trifluoromethyl-4-Nitrophenol Glucuronide in Edible Fillet Tissue of Rainbow Trout and Channel Catfish by Solid-Phase Extraction and Liquid Chromatography

2001 ◽  
Vol 84 (2) ◽  
pp. 392-398 ◽  
Author(s):  
Terrance D Hubert ◽  
Chue Vue ◽  
Jeff A Bernardy ◽  
Daniel L Van Horsen ◽  
Michelle I Rossulek
Keyword(s):  
Liquid Chromatography ◽  
Rainbow Trout ◽  
Solid Phase Extraction ◽  
Channel Catfish ◽  
Solid Phase ◽  
Phase Extraction ◽  
Rainbow Trout Oncorhynchus Mykiss ◽  
Sea Lampreys ◽  
Uv Visible

Abstract 3-Trifluoromethyl-4-nitrophenol (TFM) is a pesticide used for the selective control of sea lampreys (Petromyzon marinus) in stream and river tributaries of the Great Lakes. To determine concentrations of TFM and TFM glucuronide in the edible fillet tissue of fish during sea lamprey control treatments, an analytical method was developed to determine the concentrations of these residues in rainbow trout (Oncorhynchus mykiss; RBT) and channel catfish (Ictalurus punctatis; CCF). Homogenized fillets were extracted with methanol–water (80 + 20). TFM and TFM glucuronide were isolated from coextractives by C18 solid-phase extraction. TFM glucuronide was hydrolyzed to TFM by the addition of β-glucuronidase to the TFM glucuronide extract. The extracts were analyzed separately by liquid chromatography with UV–visible detection. Recoveries from TFM-fortified CCF and RBT tissues were 84.1 and 96.1%, respectively. The method detection limits (MDLs) are 2.4 ng/g for TFM-fortified tissues of CCF and 3 ng/g for those of RBT. Recoveries were 78.8 and 77%from TFM glucuronide-fortified CCF and RBT tissues, respectively. The MDLs for TFM glucuronide-fortified tissues are 3.5 and 6.9 ng/g for CCF and RBT, respectively.

Corncob Waste Based Adsorbent for Solid Phase Extraction of Tartrazine in Carbonated Drinks and Analytical Method using Ultra Performance Liquid Chromatography-Mass Spectrometry

2020 ◽  
Vol 16 (7) ◽  
pp. 924-932
Author(s):  
Yasmeen Mutlaq Ghazi Al Shamari ◽  
Saikh Mohammad Wabaidur ◽  
Abdulrahman Abdullah Alwarthan ◽  
Moonis Ali Khan ◽  
Masoom Raza Siddiqui
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Solid Phase Extraction ◽  
Solid Phase ◽  
Cost Effective ◽  
Ultra Performance Liquid Chromatography ◽  
Phase Extraction ◽  
Food Dye ◽  
Hyphenated Technique

Background : A new method has been developed for the determination of food dye tartrazine in soft drinks. Tartrazine is determined by hyphenated technique Ultra Performance Liquid Chromatography coupled with Mass spectrometry. The solid-phase extraction was used for the extraction of tartrazine. Methods: For the LC-MS analysis of tartrazine acetonitrile, water (80:20) was used as a mobile phase whereas, the C-18 column was selected as the stationary phase. The chromatographic run was allowed for 1 min. The adsorbent of the solid-phase extraction was synthesized from the waste corn cob. Results: Method found to be linear in the range of 0.1 mg L-1 - 10 mg L-1, limits of detection and quantitation were found to be 0.0165 mgL-1 and 0.055 mgL-1, respectively. Tartrazine, in the real sample, was found to be 20.39 mgL-1 and 83.26 mgL-1. Conclusion: The developed UPLC-MS method is rapid, simple, precise and can be used for the quantitative analysis of tartrazine. The solid-phase extraction also involves a cost-effective procedure for extraction as it does not involve the commercial cartridge.

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