Rapid screening and characterization of triterpene saponins in Acanthopanax senticosus leaves via untargeted MSAll and SWATH techniques on a quadrupole time of flight mass spectrometry

2019 ◽  
Vol 170 ◽  
pp. 68-82 ◽  
Author(s):  
Yong-Gang Xia ◽  
Feng-Qiu Gong ◽  
Xin-Dong Guo ◽  
Yan Song ◽  
Chen-Xue Li ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Time Of Flight ◽  
Rapid Screening ◽  
Triterpene Saponins ◽  
Acanthopanax Senticosus ◽  
Flight Mass Spectrometry

Rapid Screening and Characterization of Triterpene Saponins from the Root of Phytolacca acinosa Roxb by High-Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry

2021 ◽  
Author(s):  
Yun Ling ◽  
Yue Zhu ◽  
Qiao Gan ◽  
Guilan Li ◽  
Zefan Luo ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Electrospray Ionization ◽  
High Performance ◽  
Time Of Flight ◽  
Rapid Screening ◽  
Triterpene Saponins ◽  
Flight Mass Spectrometry

Abstract Triterpene saponins (TSs) are important bioactive constituents with structural diversity widely distributed in many plants. The root of Phytolacca acinosa Roxb (RPa) has been used as a traditional Chinese medicine. However, TSs as the main active ingredients in RPa have not been fully characterized. Here, we profiled TSs from RPa by high-performance liquid chromatography coupled to electrospray ionization and quadrupole time-of-flight mass spectrometry (HPLC-ESI-QTOF-MS/MS). We tentatively identified 29 TSs, including 13 that had not been reported previously from this plant. This study indicates that HPLC-ESI-QTOF-MS/MS is an effective and rapid method for the characterization of complicated TSs in herbal extracts.

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