scholarly journals Reducing relative response factor variation using a multidetector approach for extractables and leachables (E&L) analysis to mitigate the need for uncertainty factors

2020 ◽  
Vol 186 ◽  
pp. 113334
Author(s):  
Mark Anderson Jordi ◽  
Kevin Rowland ◽  
Weixi Liu ◽  
Xingluan Cao ◽  
Jie Zong ◽  
...  
2004 ◽  
Vol 53 (10) ◽  
pp. 1139-1147 ◽  
Author(s):  
Yuichi HORII ◽  
Takao KATASE ◽  
Yun-Seok KIM ◽  
Nobuyoshi YAMASHITA

Molecules ◽  
2020 ◽  
Vol 25 (17) ◽  
pp. 3881
Author(s):  
Ying Qian ◽  
Magdalena Rudzińska ◽  
Anna Grygier ◽  
Roman Przybylski

Triacylglycerols (TGs) are the most common compounds in food lipids, accounting for 95% of the weight of edible oils. The aim of this study was to scrutinize a procedure for quantitatively assessing possible adulteration of olive and rapeseed oil through GC-FID analysis of TGs. The recovery of TG standards ranged from 21% to 148%, and the relative response factor (RRF) ranged from 0.42 to 2.28. The limits of detection were in the range of 0.001 to 0.330 µg/mL, and the limits of quantitation from 0.001 to 1.000 µg/mL. The validated method was used to determine the TGs in olive oil (OO), refined rapeseed oil (RRO), and their blends. Eight TGs were detected in refined rapeseed oil, and 10 in olive oil. The addition of 1% of olive oil to rapeseed oil or vice versa can be detected using this method. Three triacylglycerols were pinpointed as indicators of adulteration of rapeseed oil with olive oil (PPO, PPL, PSO). The method described here can be used for controlling the quality of these oils.


2015 ◽  
Vol 103 ◽  
pp. 188-195 ◽  
Author(s):  
Kristen M. Foley ◽  
Patrick Dolwick ◽  
Christian Hogrefe ◽  
Heather Simon ◽  
Brian Timin ◽  
...  

2012 ◽  
Vol 70 ◽  
pp. 111-116 ◽  
Author(s):  
Bart M.J. De Spiegeleer ◽  
Matthias D’Hondt ◽  
Elien Vangheluwe ◽  
Kirsten Vandercruyssen ◽  
Bart V.I. De Spiegeleer ◽  
...  

1996 ◽  
Vol 123 (1-4) ◽  
pp. 45-53 ◽  
Author(s):  
Luigi Turrio-Baldassarri ◽  
Alessandro di Domenico ◽  
Annarita Fulgenzi ◽  
Cinzia La Rocca ◽  
Nicola Iacovella ◽  
...  

2012 ◽  
Vol 62 (9) ◽  
pp. 1061-1074 ◽  
Author(s):  
Jeremy Avise ◽  
Rodrigo Gonzalez Abraham ◽  
Serena H. Chung ◽  
Jack Chen ◽  
Brian Lamb ◽  
...  

2011 ◽  
Vol 8 (4) ◽  
pp. 1504-1511 ◽  
Author(s):  
Dharmendra Kushwah ◽  
Haresh B. Patel ◽  
Praveen K. Sinha ◽  
Pijush K. Jana

For the determination of accurate quantity of impurities in the samples authentic impurity standards or response factors at a given wavelength must be known. In the presented work a convenient method for determination of relative response factors of impurities has been described without using an authentic impurities standard. An approach for the determination of response factors of the impurities where impurity standard is physically not available was developed and verified using different approaches. One such method was developed and verified by RP-HPLC using Cosmosil C18 MS-II column at UV 238 nm. Two different approaches were employed and the verification of correctness of approach was done using a known related substance of known response factor.


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