In vitro DNA binding studies of antiretroviral drug nelfinavir using ethidium bromide as fluorescence probe

Author(s):  
M.M.V. Ramana ◽  
Rahul Betkar ◽  
Amey Nimkar ◽  
Prasanna Ranade ◽  
Balaji Mundhe ◽  
...  
Author(s):  
Xin Yang ◽  
Wan-Hui Liu ◽  
Wei-Jun Jin ◽  
Guo-Li Shen ◽  
Ru-Qin Yu

INDIAN DRUGS ◽  
2018 ◽  
Vol 55 (12) ◽  
pp. 24-26
Author(s):  
C Akhila ◽  
◽  
P Lalitha

DNA binding studies of selected heterocyclic compounds belonging to the class of quinolinones, substituted quinolinones and thiones were carried out using ct-DNA. The binding nature of the compounds with DNA analyzed using UV-spectroscopy revealed the compounds to be DNA intercalators demonstrating the binding nature of compounds with DNA base pairs. This study is aimed at establishing a facile UV spectroscopic technique to arrive at the binding mode of DNA to ligands.


2017 ◽  
Vol 70 (15) ◽  
pp. 2589-2605 ◽  
Author(s):  
Nahid Shahabadi ◽  
Maryam Mahdavi ◽  
Avat (Arman) Taherpour ◽  
Fatemeh Ghasemhezaveh

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