Abstract
Purpose Previous evidence indicates significant associations between alcohol-use disorders (AUD) and depressive disorders and their strong links with social conditions. This study aims to investigate the association between AUD and major depressive episode (MDE) across various socio-economic groups. Methods Data from the 2014 Thai National Health Examination Survey was obtained containing a random sample of 13,177 adults aged > 20 years from the whole population. The Alcohol-Use Disorders Identification Test (AUDIT) was used to classify respondents into non-problem, hazardous drinking (score 8-15) and harmful-dependent drinking (score 16-40). MDE was identified using questions based on the DSM-IV. Adjusted odds ratios (AOR) and 95% confidence intervals (CI) were calculated using logistic regression to determine the strength of associations. Results The prevalence of hazardous, harmful-dependent drinking and MDE was 10.3%, 1.9% and 2.5%, respectively. The association between MDE and AUD was modified by education level, wealth index and area of residence, with education having the largest effect (AOR=1.23, 95% CI: 0.55, 2.76 among those completing primary school only and AOR=15.19, 95% CI: 9.5, 24.29 among those completing secondary school or higher). Conclusion Socio-economic factors modify the association between alcohol-use disorder and depressive disorder among Thai people.