Validation of Stroke Diagnosis in the National Registry of Hospitalized Patients in the Czech Republic

Background: There are few contemporary epidemiological data on stroke for Central Europe. We performed a population-based study evaluating the incidence of stroke, stroke types, and ischemic stroke (IS) subtypes in Brno, the second biggest city in the Czech Republic (CR). Methods: Using the National Registry of Hospitalized Patients, and hospital databases, we identified all patients hospitalized with a stroke diagnosis in Brno hospitals in 2011. For Brno residents with validated stroke diagnosis, we calculated (a) the overall incidence of hospitalized stroke, (b) incidence rates for IS, subarachnoid hemorrhage (SAH) and intracerebral hemorrhage (ICH), and (c) incidence rates for IS subtypes. We calculated the average annual age- and sex-standardized incidence (European Standard Population and World Health Organization), to compare our results with other studies. Results: The overall crude incidence of stroke in Brno was 213/100,000 population. The incidence of stroke for stroke types were as follows: SAH, 6.9; ICH, 26.4; and IS, 180 cases per 100,000 population, respectively. The WHO-standardized annual stroke incidence was 107 for all strokes and 88 for IS, 14.4 for ICH, and 5 for SAH. For IS subtypes, the WHO-standardized incidence was large artery atherosclerosis 25.8, cardioembolism 27.8, lacunar 21.6, other determined etiology 6.2, and undetermined etiology 6.5 cases per 100,000 population. Conclusions: The stroke incidence is lower than that previously reported for the CR and Eastern Europe probably reflecting socioeconomic changes in post-communistic countries in the region. These findings could contribute to stroke prevention strategies and influence health policies.

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The Factors Influencing Economic Efficiency of the Hospital Bed Care in Terms of the Regional Allowance Organizations

Review of Economic Perspectives ◽

10.2478/revecp-2014-0012 ◽

2014 ◽

Vol 14 (3) ◽

pp. 233-248 ◽

Cited By ~ 4

Author(s):

Ivana Vaňková ◽

Iveta Vrabková

Keyword(s):

Czech Republic ◽

Length Of Stay ◽

Technical Efficiency ◽

Average Length ◽

Allocative Efficiency ◽

Hospitalized Patients ◽

Point Of View ◽

The Czech Republic ◽

Average Length Of Stay ◽

Hospital Bed

Abstract This paper aims to provide an efficiency evaluation of selected hospital bed care providers during years 2010 -2012 with respect to selected factors: The size of the hospital establishment according to number of beds, number of hospitalized patients, the average length of stay per a patient in care, total staff cost calculated per bed, total revenues calculated per bed, and total costs calculated per bed. For this purpose, hospitals providing primarily acute bed care were chosen. From the legal point of view, they are allowance organizations of a particular region. The evaluation concerns both allocative efficiency and technical efficiency. The allocative efficiency is treated from the proper algorithm point of view and it compares total costs calculated per bed with total revenues calculated per bed. A method denominated Data Envelopment Analysis was applied for the calculation of the technical efficiency of units. To be more specific, it was input-oriented model with constant returns to scale (CCR). The input parameters involve the number of beds, the average length of stay and costs per day of stay. Output parameters were as follows: Bed occupancy in days and the number of hospitalized patients. The data published by the Institute of Health Information and Statistic of the Czech Republic and by ÚFIS system (the Data Base of Ministry of Finance of the Czech Republic) were used as the source of data. The evaluation implies that only three hospitals were economically-effective: Silesian Hospital in Opava, Hospital Jihlava, and TGM Hospital Hodonín. The most significant factor influencing the efficiency was determined - the average length of stay.

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Neonatal outcomes after fetal exposure to methadone and buprenorphine: national registry studies from the Czech Republic and Norway

Addiction ◽

10.1111/add.14192 ◽

2018 ◽

Vol 113 (7) ◽

pp. 1286-1294 ◽

Cited By ~ 14

Author(s):

Blanka Nechanská ◽

Viktor Mravčík ◽

Svetlana Skurtveit ◽

Ingunn Olea Lund ◽

Roman Gabrhelík ◽

...

Keyword(s):

Czech Republic ◽

National Registry ◽

Neonatal Outcomes ◽

Fetal Exposure ◽

The Czech Republic

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Socioeconomic characteristics of women with substance use disorder during pregnancy and neonatal outcomes in their newborns: A national registry study from the Czech Republic

Drug and Alcohol Dependence ◽

10.1016/j.drugalcdep.2020.107933 ◽

2020 ◽

Vol 209 ◽

pp. 107933

Author(s):

Viktor Mravčík ◽

Blanka Nechanská ◽

Roman Gabrhelík ◽

Marte Handal ◽

Milada Mahic ◽

...

Keyword(s):

Substance Use ◽

Czech Republic ◽

Substance Use Disorder ◽

National Registry ◽

Neonatal Outcomes ◽

Registry Study ◽

The Czech Republic ◽

Socioeconomic Characteristics

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Development of percutaneous coronary interventions in the Czech Republic in 2005-2018. Results of the National Registry of Cardiovascular Interventions

Intervenční a akutní kardiologie ◽

10.36290/kar.2020.015 ◽

2020 ◽

Vol 19 (1) ◽

pp. 25-29

Author(s):

Michael Želízko ◽

Světlana Drábková ◽

Ingrid Kováčová ◽

Martin Mates

Keyword(s):

Czech Republic ◽

National Registry ◽

Percutaneous Coronary Interventions ◽

The Czech Republic ◽

Coronary Interventions ◽

Percutaneous Coronary ◽

Cardiovascular Interventions

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747Incidence of anencephaly in the Czech Republic: Long-term population based study

International Journal of Epidemiology ◽

10.1093/ije/dyab168.618 ◽

2021 ◽

Vol 50 (Supplement_1) ◽

Author(s):

Antonin Sipek ◽

Vladimir Gregor ◽

Jan Klaschka ◽

Marek Maly ◽

Antonin Sipek

Keyword(s):

Czech Republic ◽

Population Based ◽

National Registry ◽

Ultrasound Screening ◽

Population Based Study ◽

The Czech Republic ◽

Exact Test ◽

Total Incidence ◽

The Central Nervous System

Abstract Background Anencephaly is a lethal anomaly of the central nervous system from the group of neural tube defects. The main goal of our study was to evaluate the incidence of anencephaly (and its possible trends) during the 53 years period. Methods For this study, we used data from the National Registry of Congenital Anomalies of the Czech Republic. We analysed the incidence of anencephaly in births and in prenatally diagnosed cases during the 1964-2016 period. We also evaluated maternal age in these cases. The statistical analysis was performed by Poisson regression and Fisher's exact test. Results During the study period there were 6 891 062 children born in the Czech Republic. Among those, 1232 children were born with anencephaly. Another 966 cases of anencephaly were diagnosed during prenatal diagnosis and these pregnancies were electively terminated, the total number of anencephaly cases was 2198. The total incidence of anencephaly significantly decreased during the study period (p = 0.0136). The incidence in births decreased significantly as well (p < 0.001). We found statistically higher incidence of anencephaly in elder mothers (42 years and over). Conclusions Gradual implementation of ultrasound prenatal diagnostics started in the 80s of the last century and lead to a very significant decrease in the incidence of anencephaly cases in births. Additionally, the total incidence of anencephaly decreased significantly as well. Key messages Incidence of anencephaly in births decreased rapidly with gradual implementation of population wide ultrasound screening.

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Comparison of Therapies in MS Patients After the First Demyelinating Event in Real Clinical Practice in the Czech Republic: Data From the National Registry ReMuS

Frontiers in Neurology ◽

10.3389/fneur.2020.593527 ◽

2021 ◽

Vol 11 ◽

Author(s):

Zbyšek Pavelek ◽

Lukáš Sobíšek ◽

Jana Šarláková ◽

Pavel Potužník ◽

Marek Peterka ◽

...

Keyword(s):

Czech Republic ◽

Clinical Practice ◽

National Registry ◽

Term Therapy ◽

The Czech Republic ◽

Significant Difference ◽

The Central Nervous System ◽

Edss Score ◽

Long Term Therapy ◽

Real Clinical Practice

Background: Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system. Well-established drugs used for MS patients after the first demyelinating event in the Czech Republic include glatiramer acetate (GA), interferon beta-1a (IFNβ-1a), IFN beta-1b (IFNβ-1b), peginterferon beta-1a (peg-IFNβ-1a), and teriflunomide.Objective: The objective of this observational study was to compare the effectiveness of the abovementioned drugs in patients with MS who initiated their therapy after the first demyelinating event. Patients were followed for up to 2 years in real clinical practice in the Czech Republic.Methods: A total of 1,654 MS patients treated after the first demyelinating event and followed up for 2 years were enrolled. Evaluation parameters (endpoints) included the annualized relapse rate (ARR), time to next relapse, change in the Expanded Disability Status Scale (EDSS) score, and time of confirmed disease progression (CDP). When patients ended the therapy before the observational period, the reason for ending the therapy among different treatments was compared.Results: No significant difference was found among the groups of patients treated with IFNβ-1a/1b, GA, or teriflunomide for the following parameters: time to the first relapse, change in the EDSS score, and the proportion of patients with CDP. Compared to IFNβ-1a (44 mcg), a significant increase in the percentage of relapse-free patients was found for GA, but this treatment effect was not confirmed by the validation analysis. Compared to the other drugs, there was a significant difference in the reasons for terminating GA therapy.Conclusion: Small differences were found among GA, IFNβ and teriflunomide therapies, with no significant impact on the final outcome after 2 years. Therefore, in clinical practice, we recommend choosing the drug based on individual potential risk from long-term therapy and on patient preferences and clinical characteristics.

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