scholarly journals Antibody response to homologous epitopes of Epstein-Barr virus, Mycobacterium avium subsp. paratuberculosis and IRF5 in patients with different connective tissue diseases and in mouse model of antigen-induced arthritis

2020 ◽  
Vol 3 ◽  
pp. 100048 ◽  
Author(s):  
Marco Bo ◽  
Magdalena Niegowska ◽  
Hayley L. Eames ◽  
Hannah Almuttaqi ◽  
Giannina Arru ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Mouse Model ◽  
Antibody Response ◽  
Mycobacterium Avium ◽  
Epstein Barr Virus ◽  
Connective Tissue Diseases ◽  
Mycobacterium Avium Subsp ◽  
Barr Virus ◽  
Epstein Barr ◽  
Mycobacterium Avium Subsp Paratuberculosis

Are Mycobacterium avium subsp. paratuberculosis and Epstein–Barr virus triggers of multiple sclerosis in Sardinia?

2012 ◽  
Vol 18 (8) ◽  
pp. 1181-1184 ◽  
Author(s):  
Davide Cossu ◽  
Speranza Masala ◽  
Eleonora Cocco ◽  
Daniela Paccagnini ◽  
Jessica Frau ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Mycobacterium Avium ◽  
Epstein Barr Virus ◽  
Mycobacterium Avium Subsp ◽  
Healthy Controls ◽  
Humoral Immune ◽  
Barr Virus ◽  
Protein Map ◽  
Epstein Barr ◽  
Mycobacterium Avium Subsp Paratuberculosis

Sardinia acts as an ideal setting for multiple sclerosis (MS) studies because its prevalence of MS is one of the highest worldwide. Several pathogens have been investigated amongst 119 Sardinian MS patients and 117 healthy controls to determine whether they might have a role in triggering MS in genetically predisposed individuals. Mycobacterium avium subsp. paratuberculosis (MAP) and Epstein Barr virus DNA were detected in 27.5% and 17.3%, respectively, of the MS patients. Moreover an extremely high humoral immune response against MAP recombinant protein MAP FprB (homologous to human myelin P0) was observed, whereas no significant results were found against Mycobacterium tuberculosis FprA and Helicobacter pylori HP986 protein.

Quantitative analysis of shedding of Epstein-Barr virus in saliva from patients with connective tissue diseases: a pilot study

2013 ◽  
Vol 52 (7) ◽  
pp. 887-890 ◽  
Author(s):  
Tomoe Kuhara ◽  
Daisuke Watanabe ◽  
Natsuko Ishida ◽  
Yasuhiko Tamada ◽  
Yoshinari Matsumoto ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Pilot Study ◽  
Connective Tissue ◽  
Epstein Barr Virus ◽  
Connective Tissue Diseases ◽  
Barr Virus ◽  
Epstein Barr
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