Assessment of serum trace elements and electrolytes in children with childhood and atypical autism

2017 ◽  
Vol 43 ◽  
pp. 9-14 ◽  
Author(s):  
Anatoly V. Skalny ◽  
Natalia V. Simashkova ◽  
Tatiana P. Klyushnik ◽  
Andrei R. Grabeklis ◽  
Ivan V. Radysh ◽  
...  
Author(s):  
Priyadarsi Girija Sankar Sethy ◽  
◽  
Gandham Bulliyya ◽  
Tapash Ranjan Rautray ◽  
Shuchismita Behera ◽  
...  

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Yasemin Ucal ◽  
Muhittin Serdar ◽  
Cansu Akın-Levi ◽  
Zeynep Zulfiye Yıldırım-Keles ◽  
Cem Turam ◽  
...  

AbstractObjectivesTrace elements are essential in thyroid functioning as they incorporate into biologically important enzymes as cofactors. The placenta can either activate or inhibit the transfer of maternal trace elements to the unborn. An imbalance of maternal trace elements in pregnancy may affect both maternal and newborn thyroid function.MethodsBlood samples from 315 lactating mothers were collected in the first 48 h after delivery and evaluated for selenium (Se), copper (Cu), manganese (Mn), and zinc (Zn) using flame atomic absorption spectroscopy (FAAS) and quadrupole inductively coupled plasma-mass spectrometer (ICP-MS). Thyroid hormones and auto-antibodies (thyroid-stimulating hormone (TSH), free T3 (fT3), free T3 (fT4), anti–thyroid peroxidase (anti-TPO), and antithyroglobulin (anti-TG)) were analyzed in maternal blood using an electro-chemiluminescence immunoassay (ECLIA). Between 48 and 72 postpartum hours, spot blood samples were used for newborn screening-TSH measurement. Correlation and multivariate analyses were performed to evaluate the effect of maternal trace element levels on newborn screening-TSH levels.ResultsThe medians (min-max) of maternal Se (45.16 µg/L (21.28–79.04)), Cu (210.10 µg/dL (117.04–390.64)), Mn (2.11 µg/L (0.20–3.46)), and Zn (0.43 mg/L (0.24–0.66)) were determined. A positive correlation was detected between Zn and maternal TSH levels (r=0.12, p < 0.05). Newborn screening-TSH was significantly correlated with maternal Cu (r=0.14, p < 0.01). Similarly, Cu exhibited weak associations in clustering analysis while others shared common clusters with newborn-screening TSH.ConclusionsThere was no significant association between most of the maternal serum trace elements and maternal thyroid hormone parameters, with an only exception between maternal Zn and maternal serum TSH. Finally, the association between maternal serum Cu levels and newborn screening-TSH levels may highlight the importance of maternal Cu levels on the newborn thyroid health.


2009 ◽  
Vol 55 (5) ◽  
pp. 407-411 ◽  
Author(s):  
Arthur LEIBOVITZ ◽  
Emilia LUBART ◽  
Julio WAINSTEIN ◽  
Yosef DROR ◽  
Refael SEGAL

Author(s):  
Kursat Gundogan ◽  
Yasemin Emur Gunay ◽  
Nurhayat Tugra Ozer ◽  
Gulsah G. Sahin ◽  
Nilgun Ozlem Alptekinoglu Mendil ◽  
...  

2009 ◽  
Vol 39 (1) ◽  
pp. 23-27 ◽  
Author(s):  
G. C. Gerli ◽  
R. Mongiat ◽  
M. T. Sandri ◽  
A. Agostoni ◽  
V. Gualandri ◽  
...  

Cancer ◽  
1987 ◽  
Vol 60 (8) ◽  
pp. 1842-1846 ◽  
Author(s):  
Yves Beguin ◽  
Francoise Brasseur ◽  
Georges Weber ◽  
Jean Bury ◽  
Jeanne-Marie Delbrouck ◽  
...  

Author(s):  
Naoual El Omri ◽  
Fadwa Mekouar ◽  
Naoufal Assoufi ◽  
Abdelkhalek Maaroufi ◽  
Jihane Smaali ◽  
...  

Background: Several trace elements have been implicated in the etiology of type 2 diabetes, they can influence the onset or pathogenesis of diabetes in various ways including disruption of normal metabolism of glucose and insulin. The purpose of this work is to evaluate the serum status of copper, zinc, selenium, chromium and manganese in Moroccan type 2 diabetics compared to control group.Methods: Blood samples from 100 type 2 diabetics and 90 control subjects were analyzed for blood glucose, glycated hemoglobin (only for diabetics), lipid status and serum trace elements concentrations.Results: Glucose and triglyceride values were statistically higher in diabetics; while those of HDL-cholesterol were lower. Concentrations of zinc, selenium, chromium, and manganese were lower in diabetics compared to controls. In contrast, copper concentrations were higher.Conclusions: The status of trace elements is impaired in type 2 diabetics compared to a control group.


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