A follow-up study of mucociliary clearance and trace element and mineral status in children with chronic rhinosinusitis before and three months after endoscopic sinus surgery

2021 ◽  
pp. 126812
Author(s):  
Svetlana I. Alekseenko ◽  
Sergey Karpischenko ◽  
Sergey Artyushkin ◽  
Svetlana Barashkova ◽  
Mikhail Karganov ◽  
...  
Keyword(s):  
Trace Element ◽  
Chronic Rhinosinusitis ◽  
Endoscopic Sinus Surgery ◽  
Mucociliary Clearance ◽  
Sinus Surgery ◽  
Mineral Status ◽  
Follow Up Study

scholarly journals Twelve-year follow-up study after endoscopic sinus surgery in patients with chronic rhinosinusitis with nasal polyposis

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Lien Calus ◽  
Nicholas Van Bruaene ◽  
Cedric Bosteels ◽  
Sarah Dejonckheere ◽  
Thibaut Van Zele ◽  
...  
Keyword(s):  
Chronic Rhinosinusitis ◽  
Endoscopic Sinus Surgery ◽  
Nasal Polyposis ◽  
Sinus Surgery ◽  
Follow Up Study

Relationship between Olfactory Acuity and Peak Expiratory Flow during Postoperative Follow-up in Chronic Rhinosinusitis Associated with Asthma

2010 ◽  
Vol 119 (11) ◽  
pp. 749-754 ◽  
Author(s):  
Katsuhisa Ikeda ◽  
Hidenori Yokoi ◽  
Takeshi Kusunoki ◽  
Tatuya Saitoh ◽  
Toru Yao ◽  
...  
Keyword(s):  
Chronic Rhinosinusitis ◽  
Peak Expiratory Flow ◽  
Endoscopic Sinus Surgery ◽  
Sinus Surgery ◽  
Olfactory Acuity ◽  
Smell Test ◽  
Initial Symptoms ◽  
Lower Airways ◽  
Expiratory Flow

Objectives The link between nasal and bronchial disease has been studied extensively for chronic rhinosinusitis and asthma. The concept of “united airway allergy” has become widely accepted in the past decade. We evaluated the relationship between the upper and lower airways during follow-up after endoscopic sinus surgery by monitoring sinonasal and pulmonary functions. Methods Thirty-nine subjects with chronic rhinosinusitis associated with bronchial asthma were entered in this study. A self smell test using stick-type odorant materials was carried out daily to evaluate postoperative recurrence of sinonasal disease. Each patient was assessed for peak expiratory flow (PEF) 3 times daily. Results The average (±SD) scores of initial symptoms were 8.3 ± 2.2, which was significantly decreased to 1.5 ± 1.4 by 3 months after operation. During postoperative follow-up, 25 of 39 patients showed no decrease in PEF, whereas the other 14 patients had at least 1 episode of a significant decline in PEF. In the postoperative course, with respect to the self smell test, 24 patients showed no aggravation of smell, but 15 patients had episode(s) of decreased olfaction. Twelve patients demonstrated worsening on the smell test concomitant with a decreased PEF. A discrepancy between olfactory acuity and pulmonary function was recognized in 5 patients. There were 22 patients with a good prognosis of parameters of both the upper and lower airways. Conclusions Daily monitoring of both upper and lower respiratory tract functions clearly revealed dual relationships, indicating that worsening of sinusitis accompanies asthma exacerbation. Appropriate measures of the upper and lower airways following endoscopic sinus surgery can be used to predict patient outcome.

Predictors of disease progression after endoscopic sinus surgery in patients with chronic rhinosinusitis

2019 ◽  
Vol 133 (8) ◽  
pp. 678-684 ◽  
Author(s):  
K Tsuzuki ◽  
K Hashimoto ◽  
K Okazaki ◽  
H Nishikawa ◽  
M Sakagami
Keyword(s):  
Disease Progression ◽  
Chronic Rhinosinusitis ◽  
Endoscopic Sinus Surgery ◽  
Frontal Sinus ◽  
Early Period ◽  
Functional Endoscopic Sinus Surgery ◽  
Sinus Surgery ◽  
Eosinophilic Chronic Rhinosinusitis ◽  
Operative Findings

AbstractObjectiveThis study aimed to determine the predictors of disease progression after functional endoscopic sinus surgery in patients with chronic rhinosinusitis.MethodA total of 281 adult chronic rhinosinusitis patients who underwent primary bilateral functional endoscopic sinus surgery between 2007 and 2017 and had at least 12 months of follow-up endoscopic evaluation were examined. Patients were divided into eosinophilic (n= 205) and non-eosinophilic chronic rhinosinusitis groups (n= 76). In order to determine adverse factors, post-operative endoscopic appearance scores were analysed in relation to the pre- and intra-operative findings using multiple regression analyses.ResultsThe post-operative course of eosinophilic cases deteriorated over time, like the early period for non-eosinophilic cases. Frontal sinus polyps recurred early in eosinophilic chronic rhinosinusitis. Multivariate analyses indicated young adulthood, asthma, high computed tomography score and frontal sinus polyps as significant adverse predictors.ConclusionEarly, appropriate estimation of sinonasal conditions appears to be crucial for successful surgical management of chronic rhinosinusitis.

Reversibility of mucociliary clearance and olfaction impairment following endoscopic sinus surgery: a prospective observational study

2021 ◽  
pp. 1-6
Author(s):  
V Hema ◽  
G Rebekah ◽  
R Kurien
Keyword(s):  
Chronic Rhinosinusitis ◽  
Endoscopic Sinus Surgery ◽  
Prospective Observational Study ◽  
Nasal Polyposis ◽  
Mucociliary Clearance ◽  
Functional Endoscopic Sinus Surgery ◽  
Sinus Surgery ◽  
Primary Surgery ◽  
Operative Care ◽  
Olfactory Thresholds

Abstract Objective Chronic rhinosinusitis is associated with altered mucociliary clearance and olfaction. The study aimed to analyse the reversibility of impairment and endoscopic factors predicting changes in mucociliary clearance and olfactory parameters. Methods This prospective study included patients undergoing functional endoscopic sinus surgery for medically refractory chronic rhinosinusitis. Pre- and post-operative measurements of mucociliary clearance, olfactory thresholds, and identification scores were recorded. Results Of the 96 patients, 65.6 per cent had polyposis and 80.2 per cent underwent primary surgery. Improvements in mucociliary clearance and olfaction scores were seen in all patients, with greater reversibility of impairment in patients with polyposis and in those who underwent revision surgery. The presence of polyps correlated significantly with changes in mucociliary clearance and olfaction. Conclusion The study highlights improvements in mucociliary clearance, olfactory thresholds and identification scores after functional endoscopic sinus surgery in chronic rhinosinusitis with or without nasal polyposis, as well as for primary and revision surgeries. Adequate post-operative care and prevention of polyps recurrence help to improve mucociliary clearance and olfaction scores.

scholarly journals Efficacy of Mitomycin-C for Prevention of Adhesion Formation after Functional Endoscopic Sinus Surgery in Cases of Chronic Rhinosinusitis: A Prospective Cross-sectional Study

2014 ◽  
Vol 7 (3) ◽  
pp. 100-104 ◽  
Author(s):  
Anilkumar Suryadev Harugop ◽  
Ramesh Mudhol ◽  
Amit Nargund ◽  
Shailaja Hugar ◽  
Amrit Kapoor ◽  
...  
Keyword(s):  
Chronic Rhinosinusitis ◽  
Mitomycin C ◽  
Endoscopic Sinus Surgery ◽  
Adhesion Formation ◽  
Cross Sectional Study ◽  
Functional Endoscopic Sinus Surgery ◽  
Sinus Surgery ◽  
Sectional Study ◽  
Cross Sectional

ABSTRACT Objective To determine whether topical application of mitomycin- C at the conclusion of FESS decreases the incidence of postoperative adhesion formation. Study design Prospective cross-sectional study. Materials and methods Between June 2011 and June 2013, 42 patients (65 sides) aged between 16 and 66 years diagnosed to have chronic rhinosinusitis (CRS) underwent FESS. At the conclusion of the ESS, cotton ribbon wick soaked with 1 ml mitomycin-C (0.4 mg/ml) was placed in right/left/ both middle meati, near the widened sinus ostia for a period of 4 minutes. Following application, nasal cavity was irrigated with sterile normal saline. Patients were examined weekly for 1 month after surgery. Additional examinations were done at the end of 2nd and 3rd months postoperatively. At the end of 3 months follow-up, the outcome was assessed subjectively by symptoms and objectively by endoscopic findings. Results At the end of 3 months follow-up, a significant decrease (80%) in symptom scores was observed (6.64 ± 1.80, p < 0.001). Similarly in sinonasal outcome test (SNOT) score we observed a significant reduction (71%) in scores (17.76 ± 8.17, p < 0.001) and 3.1% cases showed adhesions. Conclusion CRS patients have remarkable improvement in their symptoms after FESS. Topical application of mitomycin-C at the conclusion of FESS/ESS has a role in prevention of adhesion formation. How to cite this article Harugop AS, Mudhol R, Nargund A, Hugar S, Kapoor A, Shetty R. Efficacy of Mitomycin-C for Prevention of Adhesion Formation after Functional Endoscopic Sinus Surgery in Cases of Chronic Rhinosinusitis: A Prospective Cross-sectional Study. Clin Rhinol An Int J 2014;7(3):100-104.

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