scholarly journals P1.03-046 Selection of Subjects at High-Risk for LDCT Lung Cancer Screening Using a Molecular Panel: Results by the ITALUNG Biomarker Study

2017 ◽  
Vol 12 (1) ◽  
pp. S570-S571
Author(s):  
Francesca Carozzi ◽  
Laura Carrozzi ◽  
Fabio Falaschi ◽  
Andrea Lopes Pegna ◽  
Mario Mascalchi ◽  
...  
2020 ◽  
Vol 7 (1) ◽  
pp. e000811
Author(s):  
Oluf Dimitri Røe

Screening a population for a potentially deadly disease, the ultimate goal must be to prevent morbidity and mortality from this disease for the whole population. Unlike breast cancer or cervical cancer screening, where all women are screened after a certain age, CT screening for lung cancer has been based on selection of putative high-risk individuals based on age and smoking cut-off values. The type of selection used leaves too many high-risk individuals behind. The solution is to use only validated risk prediction models for selection.


2020 ◽  
Vol 95 (2) ◽  
pp. 95-103
Author(s):  
Seung Hun Jang

The results of large-scale clinical studies have shown that the lung cancer mortality rate can be reduced by lung cancer screening using low-dose computed tomography (LDCT) in high-risk populations. Lung cancer screening requires rigorous quality control to ensure that imaging can be introduced into evidence-based medical systems and that results can be effectively delivered to examinees. Cessation of smoking is indispensable for reducing mortality in parallel with lung cancer screening. Pulmonary nodules found in LDCT during the Korean National Lung Cancer Screening are categorized according to their characteristics, size, and time of discovery based on the Lung Imaging Reporting And Data System (Lung-RADS); management guidelines are followed according to categorization. To improve the efficiency of lung cancer screening, studies are currently ongoing to enable selection of high-risk groups using lung cancer prediction models and biomarkers. Based on the risk estimation classification of lung cancer, it is expected that the selection of screening subjects and the screening cycle can be differentiated, which will increase the efficiency of screening, reduce the risk of unnecessary radiation exposure, and reduce the cost of screening.


2019 ◽  
Vol 29 (1) ◽  
pp. 19-24
Author(s):  
Wei Hao Kok ◽  
Andrea Ban Yu-Lin ◽  
Shamsul Azhar Shah ◽  
Faisal Abdul Hamid

Background: Lung cancer is the second most common cause of cancer-related death and the third most common cancer in Malaysia. The rising prevalence of lung cancer suggests the need to consider disease screening for early detection, especially in the high-risk population, as it offers the best chance of cure. Objectives: The study aims to determine the willingness of high-risk respondents to participate in a lung cancer screening programme if made available to them, and to determine their attitude towards lung cancer screening and explore factors that might affect participation in a screening programme. Method: This is a cross-sectional, descriptive study over 6 months conducted in adult patients attending medical clinics in Universiti Kebangsaan Malaysia Medical Centre (UKMMC) using face-to-face administered questionnaires. Results: In total 180 respondents were analysed. There were 177 (98.3%) males. Mean age was 59.8 ± 9.1 years. Of the respondents, 138 (76.7%) had poor knowledge about cancer screening. Former smokers comprised 119 (66.1%) of the participants, and 61 (33.9%) were current smokers. In total, 141 (78.3%) respondents indicated willingness to participate in a lung cancer screening programme. Out of this group, 68 (48.2%) respondents were unwilling to pay for the procedure. Only 18 (12.8%) were unwilling to undergo lung cancer treatment if detected early. Conclusions: Awareness about general cancer screening is low. Our study showed that when informed of their high-risk status, respondents were willing to participate in lung cancer screening. There should be more health programmes to promote and raise awareness about lung cancer.


CHEST Journal ◽  
2004 ◽  
Vol 126 (4) ◽  
pp. 749S
Author(s):  
Gregory M. Loewen ◽  
DongFeng Tan ◽  
Donald Klippenstein ◽  
Zachary Grossman ◽  
Enriqueta Nava ◽  
...  

BMJ Open ◽  
2015 ◽  
Vol 5 (7) ◽  
pp. e008254 ◽  
Author(s):  
Noor Ali ◽  
Kate J Lifford ◽  
Ben Carter ◽  
Fiona McRonald ◽  
Ghasem Yadegarfar ◽  
...  

2013 ◽  
Vol 2 ◽  
pp. 114-120 ◽  
Author(s):  
Kinga Kiszka ◽  
Lucyna Rudnicka-Sosin ◽  
Romana Tomaszewska ◽  
Małgorzata Urbańczyk-Zawadzka ◽  
Maciej Krupiński ◽  
...  

Lung Cancer ◽  
2020 ◽  
Vol 148 ◽  
pp. 79-85
Author(s):  
Mark R. Waddle ◽  
Stephen J. Ko ◽  
Jackson May ◽  
Tasneem Kaleem ◽  
Daniel H. Miller ◽  
...  

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