scholarly journals P48.11 Anlotinib Versus Chemotherapy as a Third-Line or Further Treatment for Advanced Small Cell Lung Cancer

2021 ◽  
Vol 16 (3) ◽  
pp. S504
Author(s):  
Y. Wang ◽  
X. Ling ◽  
S. Cao ◽  
J. Li ◽  
Y. Zhou ◽  
...  
2014 ◽  
Vol 15 (2) ◽  
pp. 110-118 ◽  
Author(s):  
Demetrios Simos ◽  
Golmehr Sajjady ◽  
Melissa Sergi ◽  
Mun Sem Liew ◽  
Raffaele Califano ◽  
...  

2021 ◽  
Vol 16 (10) ◽  
pp. S1078
Author(s):  
T. Beninato ◽  
S. Manglaviti ◽  
E. Zattarin ◽  
G. Apollonio ◽  
E. Galli ◽  
...  

2012 ◽  
Vol 7 (10) ◽  
pp. 1594-1601 ◽  
Author(s):  
Vassiliki A. Papadimitrakopoulou ◽  
Jean-Charles Soria ◽  
Annette Jappe ◽  
Valentine Jehl ◽  
Judith Klimovsky ◽  
...  

Immunotherapy ◽  
2021 ◽  
Author(s):  
Lei Song ◽  
Rengui Zhou ◽  
Xiangyong Li ◽  
Dejian Pan

Small-cell lung cancer (SCLC) is sensitive to chemoradiotherapy but remains to have a poor prognosis. In the immunotherapy era, chemotherapy combined with PD-L1 inhibitors has become a new first-line treatment option for advanced SCLC. The CheckMate 032 study combined a PD-1 blockade and a CTLA-4 inhibitor and found that this dual immunotherapy might be a positive treatment choice for SCLC. In our case, the patient with advanced SCLC received bevacizumab combined with dual immunotherapy over the third line with more than 12 months survival time. The overall survival time was 21.5 months from the start of the third-line treatment and 39 months from the time of extensive-disease SCLC diagnosis. The combination of a VEGF blockade and a dual immunotherapy in SCLC resulted in synergistic treatment effects. Therefore, bevacizumab might be a better adjuvant, either combined with chemotherapy or dual immunotherapy, for patients with persistent disease progression after undergoing immunotherapy.


2009 ◽  
Vol 71 (2) ◽  
pp. 117-126 ◽  
Author(s):  
Adolfo Favaretto ◽  
Giulia Pasello ◽  
Cristina Magro ◽  
Clorinda Schettino ◽  
Cesare Gridelli

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