1592 IMPACT OF COMORBIDITIES ON PERIOPERATIVE COMPLICATIONS AFTER RADICAL CYSTECTOMY FOR BLADDER UROTHELIAL CARCINOMA A TERTIARY SOUTH AMERICAN ONCOLOGY CENTER EXPERIENCE

Abstract Background: To investigate the perioperative efficacy and cost of robot-assisted radical cystectomy(RARC) and laparoscopic RC(LRC) in patients with non-advanced bladder urothelial carcinomaMethods: 156 patients with non-advanced bladder urothelial carcinoma undergoing minimally invasive radical cystectomy in our center between January 2015 and April 2020 were included. Perioperative data and hospitalization expenses were extracted from our database. All analyses were performed using SPSS 23.0 software, and p < 0.05 was considered statistically significant.Results: The proportion of male patients was 86.5%(135/156) and the median age was 65(IQR 59-71) years old. RARC had a lower PSM rate (0 vs 5.3%,P=0.051), longer median operation time(370 vs 305 min,P<0.001) and higher median hospitalization cost(20565.2 vs 15532.4$,P<0.001). There were no significant differences in intraoperative transfusion rate, anesthesia resuscitation in ICU, postoperative hospital stay, 30-d complications and postoperative treatment expenses between the two groups(P=0.815,0.715, 0.817,0.92 and 0.543,respectively.)Conclusion: Short operation time and low hospitalization costs are favorable factors for LRC, but RARC may be the preferred surgical procedure for non-advanced bladder urothelial carcinoma considering the potentially low PSM rate.Trial registration: A complete informed consent was obtained from the patient and their families before the surgery.Informed consent was signed for all patients.This study was approved by the Ethics Review Committee of the Second Xiangya Hospital of Central South University

Download Full-text

Correlation between biopsy and radical cystectomy in assessing grade and depth of invasion in bladder urothelial carcinoma

Urology ◽

10.1016/s0090-4295(01)00998-0 ◽

2001 ◽

Vol 57 (6) ◽

pp. 1063-1066 ◽

Cited By ~ 28

Author(s):

Brian S Chang ◽

Hyung L Kim ◽

Ximing J Yang ◽

Gary D Steinberg

Keyword(s):

Urothelial Carcinoma ◽

Radical Cystectomy ◽

Depth Of Invasion ◽

Bladder Urothelial Carcinoma

Download Full-text

Case Report: Metachronous bilateral upper tract and bladder urothelial carcinoma: a long-term follow-up

F1000Research ◽

10.12688/f1000research.55516.1 ◽

2021 ◽

Vol 10 ◽

pp. 778

Author(s):

Agus Rizal Ardy Hariandy Hamid ◽

Fakhri Zuhdian Nasher ◽

Meilania Saraswati ◽

Sahat Matondang ◽

Chaidir Arif Mochtar

Keyword(s):

Urothelial Carcinoma ◽

Radical Cystectomy ◽

Upper Urinary Tract ◽

Urothelial Cell ◽

Laser Evaporation ◽

Ureteral Orifice ◽

Upper Tract ◽

Bladder Urothelial Carcinoma ◽

Carcinoma Of The Bladder ◽

The Right

Background: Upper tract urothelial carcinoma (UTUC) is a malignant disease of the urothelial cell lining the upper urinary tract from renal calyces, pelvises, and ureter down to the ureteral orifice. Urothelial carcinoma is a multifocal malignant tumor which tends to reoccur after treatment. Radical cystectomy shows that upper tract recurrence occurs in 0.75% to 6.4% of patients. The occurrence of contralateral UTUC after nephroureterectomy is rarer with a prevalence of 0.5%. Case presentation: The case of a 43-year-old male with metachronous bilateral UTUC was reported. The patient had undergone gemcitabine-cysplatine neoadjuvant chemotherapy followed by radical cystectomy and orthotopic neobladder for urothelial carcinoma of the bladder cT2N0M0. Left hydronephrosis was discovered three months after the procedure. The patient was diagnosed with left UTUC cT4N0M0 of renal pyelum after a series of examinations. A left open radical nephroureterectomy was conducted to remove the mass followed by adjuvant chemotherapy. This was followed up with routine ultrasound and magnetic resonance imaging (MRI) every three months with a “tumor-free” period of 26 months. Meanwhile, the patient was re-admitted with fever and an increase in creatinine value of 4.3. After further workups, the patient was diagnosed with UTUC cT2N0M0 of the right renal pyelum. A kidney sparring approach with laser evaporation of the tumor was conducted followed by eight cycles of Gemcitabine intracavity antegrade per nephrostomy. After the regimen was finished, an MRI evaluation was conducted to assess treatment results, and the mass had decreased. Conclusions: This report showed a rare case of urothelial cell carcinoma recurrences. From bladder urothelial carcinoma to left UTUC and then to contralateral UTUC. It is important to evaluate the upper tract to reduce the risk of recurrence.

Download Full-text

Vaginal metastasis of bladder urothelial carcinoma: Description of a case and revision of literature

Archivio Italiano di Urologia e Andrologia ◽

10.4081/aiua.2017.2.156 ◽

2017 ◽

Vol 89 (2) ◽

pp. 156 ◽

Cited By ~ 1

Author(s):

Carmelo A. Di Franco ◽

Daniele Porru ◽

Giovanni Giliberto ◽

Alessandra Viglio ◽

Bruno Rovereto

Keyword(s):

Bladder Cancer ◽

Urothelial Carcinoma ◽

Radical Cystectomy ◽

Vaginal Bleeding ◽

Urothelial Cancer ◽

Vaginal Wall ◽

Rare Entity ◽

Bladder Urothelial Carcinoma ◽

Vaginal Metastasis ◽

History Of

Vaginal metastases from urothelial cancer are a rare entity and in literature, few cases are described. We report a case of a 68 year-old woman with history of bladder urothelial carcinoma underwent to radical cystectomy who came in our department after 5 months for pelvic pain and vaginal bleeding. Objective examination revealed an ulcerative, solid vaginal lesion in the upper vaginal wall. We performed a vaginal biopsy that showed urothelial carcinoma compatible with the primitive bladder cancer. The patient underwent to surgery and was sent to oncological evaluation.

Download Full-text