scholarly journals MP52-16 INTRAPARENCHYMAL THERAPY DELIVERY IN THE PROSTATE: THE ROLE OF IMAGING AND DEVICE DESIGN

2017 ◽  
Vol 197 (4S) ◽  
Author(s):  
Hoang-Kim Le ◽  
Martin Brady ◽  
King Scott Coffield ◽  
Thomas Kuehl ◽  
Raghu Raghavan ◽  
...  
Keyword(s):  
Device Design ◽  
Therapy Delivery

The Role of Physical Affordances in Multifunctional Mobile Device Design

2010 ◽  
Vol 5 (4) ◽  
pp. 40-57 ◽  
Author(s):  
Sorin Adam Matei ◽  
Anthony Faiola ◽  
David J. Wheatley ◽  
Tim Altom
Keyword(s):  
Mobile Computing ◽  
Full Advantage ◽  
Mental Models ◽  
Mobile Device ◽  
Design Theory ◽  
Cognitive Models ◽  
Device Design ◽  
Mobile Media ◽  
New Device

As designers of mobile/media-rich devices continue to incorporate more features/functionality, the evolution of interfaces will become more complex. Meanwhile, users cognitive models must be aligned with new device capabilities and corresponding physical affordances. In this paper, the authors argue that based on HCI design theory, users approach objects by building mental models starting with physical appearance. Findings suggest that users who embrace a device’s multifunctionality are prevented from taking full advantage of an array of features due to an apparent cognitive constraint caused by a lack of physical controls. The authors submit that this problem stems from established mental models and past associated behaviors of both mobile and non-mobile interactive devices. In conclusion, users expressed a preference for immediate access and use of certain physical device controls within a multi-tasking environment, suggesting that as mobile computing becomes more prevalent, physical affordances in multifunctional devices may remain or increase in importance.

The Role of Physical Affordances in Multifunctional Mobile Device Design

2012 ◽  
pp. 306-324
Author(s):  
Sorin Adam Matei ◽  
Anthony Faiola ◽  
David J. Wheatley ◽  
Tim Altom
Keyword(s):  
Mobile Computing ◽  
Full Advantage ◽  
Mental Models ◽  
Mobile Device ◽  
Design Theory ◽  
Cognitive Models ◽  
Device Design ◽  
Mobile Media ◽  
New Device

As designers of mobile/media-rich devices continue to incorporate more features/functionality, the evolution of interfaces will become more complex. Meanwhile, users cognitive models must be aligned with new device capabilities and corresponding physical affordances. In this paper, the authors argue that based on HCI design theory, users approach objects by building mental models starting with physical appearance. Findings suggest that users who embrace a device’s multifunctionality are prevented from taking full advantage of an array of features due to an apparent cognitive constraint caused by a lack of physical controls. The authors submit that this problem stems from established mental models and past associated behaviors of both mobile and non-mobile interactive devices. In conclusion, users expressed a preference for immediate access and use of certain physical device controls within a multi-tasking environment, suggesting that as mobile computing becomes more prevalent, physical affordances in multifunctional devices may remain or increase in importance.

Liposomes for Pulmonary Drug Delivery: The Role of Formulation and Inhalation Device Design

2017 ◽  
Vol 23 (3) ◽  
pp. 362-372 ◽  
Author(s):  
Abdelbary Elhissi
Keyword(s):  
Clinical Trials ◽  
Drug Release ◽  
Controlled Drug Release ◽  
Drug Carriers ◽  
Device Design ◽  
Inhalation Device ◽  
Liposome Preparation ◽  
Wide Range ◽  
Therapeutic Molecules

Liposomes are established drug carriers for inhalation owing to their safety and ability to provide controlled drug release in the lung. These carriers can entrap a wide range of therapeutic molecules for delivery in large volumes to the peripheral airways using medical nebulizers. Pressurized metered inhalers (pMDIs), soft mist inhalers (SMIs) and dry powder inhalers (DPIs) can deliver relatively small quantities of medication to the lung when compared to medical nebulizers which can deliver large volumes using simple liposome preparation techniques. Unfortunately, the shearing provided during nebulization to convert the aqueous liposome dispersions into “respirable” aerosol droplets may exert physical stress on liposome bilayers, causing losses of the originally entrapped drug. The development of successful liposome carriers for inhalation depends on two main factors which are formulation composition and nebulizer design, with the aim of reducing the detrimental effect of shearing on liposome stability and maximizing the deposition of vesicles in the ‘deep lung’. A number of nebulizable liposome formulations have reached clinical trials. For example, Arikace® (liposomal amikacin) and Pulmaquin® (liposomal ciprofloxacin) are antibacterial formulations currently in advanced stages of development. In this review, the role of liposome formulation and inhalation device design on the suitability of liposomes for eliciting controlled drug release in the lung was evaluated. Moreover, the factors contributing to the success of Arikace® in clinical trials were appraised.

scholarly journals Evaluating the role of bycatch reduction device design and fish behavior on Pacific salmon (Oncorhynchus spp.) escapement rates from a pelagic trawl

2021 ◽  
Vol 236 ◽  
pp. 105830
Author(s):  
Noëlle Yochum ◽  
Michael Stone ◽  
Karsten Breddermann ◽  
Barry A. Berejikian ◽  
John R. Gauvin ◽  
...  
Keyword(s):  
Pacific Salmon ◽  
Fish Behavior ◽  
Device Design ◽  
Bycatch Reduction

The Role of Nanoscale Silicon in Optical Interconnects

2002 ◽  
Vol 737 ◽  
Author(s):  
Philippe M. Fauchet
Keyword(s):  
Optical Interconnects ◽  
Semiconductor Industry ◽  
Building Blocks ◽  
Device Design ◽  
Major Barrier ◽  
Industry Association ◽  
Semiconductor Industry Association ◽  
Points Of View

ABSTRACTThe semiconductor industry association roadmap has identified interconnects as a major barrier to progress starting in 2010. Optical interconnects (OI) offer an attractive solution for chip-to-chip communications, however there is no general agreement on how to design them. Eventually, OI may also perform a large amount of intra-chip clocking and signaling, which implies that any chip-to-chip OI system must be designed to be compatible with intra-chip OI, from the points of view of manufacturability, architecture, and device design. We are exploring the use of nanoscale silicon for OI. This paper reports progress toward the demonstration of two basic building blocks of an OI system, namely a Si laser and a Si-based modulator.

scholarly journals Exploring the role of Design in the context of Medical Device Innovation

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Keum Hee Kimmi KO ◽  
Jessica Lea DUNN ◽  
David LAHOUD ◽  
Erez NUSEM ◽  
Karla STRAKER ◽  
...  
Keyword(s):  
Medical Device ◽  
Development Process ◽  
Product Development Process ◽  
Health Issues ◽  
Device Design ◽  
Medical Problems ◽  
Medical Device Design ◽  
Commercial Viability ◽  
Design Innovation

Technology is the leading driving force in healthcare and medical device design, however, innovations which emerge from these practices are often driven by clinical requirements. Such innovations are focused on developing products that addresses current health issues, diseases or medical problems – often lacking consideration of the end users’ needs. Design innovation advocates that user-centred design happens much earlier in the product development process so that the patient needs are prioritised. However, this emerging field is yet to be defined and explored in a medical context. This paper therefore proposes a framework of Medical Device Design Innovation to explore the role of design in medical device innovation through two medical device case studies. The proposed framework suggests a way to navigate the nuances and complexities of the medical device industry in order to put the patient first while ensuring commercial viability.

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