scholarly journals PMD15 - COMPUTER-ASSISTED (TAONET®) AND MANUAL DOSAGE CONTROL OF PATIENTS ON ORAL ANTICOAGULANT THERAPY IN ROUTINE CLINICAL PRACTICE. PRELIMINARY RESULTS OF A MULTICENTER STUDY

2018 ◽  
Vol 21 ◽  
pp. S245
Author(s):  
N. Cruz ◽  
J. Hernandez ◽  
N. López Andrés ◽  
S. Risoto ◽  
T. Soler ◽  
...  
2020 ◽  
Vol 84 (8) ◽  
pp. 1330-1338 ◽  
Author(s):  
Yutaka Ogino ◽  
Tomoaki Ishigami ◽  
Yugo Minamimoto ◽  
Yuichiro Kimura ◽  
Eiichi Akiyama ◽  
...  

2000 ◽  
Vol 83 (01) ◽  
pp. 49-53 ◽  
Author(s):  
Doris Barcellona ◽  
Paolo Contu ◽  
Gian Sorano ◽  
Vittorio Pengo ◽  
Francesco Marongiu

SummaryThe aims of this study were to investigate on the general adhesion of the patients to oral anticoagulant therapy, and particularly on the quality of life of our patients, the doctor-patient relationship and the Centre-patient relationship. For this purpose we administered a questionnaire containing 17 main questions each with a maximum of 4 secondary questions. The questionnaire was administered to two groups of 127 and 137 oral anticoagulated patients (127 males and 137 females, mean age 55 ± 19 years), followed at two Anticoagulation Clinics, in two Italian cities, Cagliari (Sardinia) and Padua (North East Italy). The cities differed in the number of patients monitored and the management modalities of anticoagulation. The results show that oral anticoagulant therapy does not limit the life-style of the patients. Only 11% of the patients complain of limitations to their daily life. Fifty-two percent believe their health has improved, and 87% are not afraid of negative consequences. The doctor-patient relationship is considered very important by 96% of patients. Seventy-eight percent refer to the Anticoagulation Clinic also for other health problems, 93% consider it important to be assessed by the doctor at the Anticoagulation Clinic, while 83% believe the doctor should always hand out the results personally. We conclude that in general oral anticoagulant therapy is accepted by the majority of patients, in spite of the need for periodic monitoring. The doctor-patient relationship should be taken into account, even in the case of a monitored, computer-assisted method of dose-adjustment.


2011 ◽  
Vol 2 (1) ◽  
pp. 9-28 ◽  
Author(s):  
Luca Masotti ◽  
Mario Di Napoli ◽  
Daniel Godoy ◽  
Daniela Rafanelli ◽  
Giancarlo Liumbruno ◽  
...  

Intracerebral haemorrhage (ICH) represents the most feared complication of therapy with vitamin K antagonists (VKA), so-called oral anticoagulant therapy (OAT). This is a real emergency in clinical practice, being burdened by high mortality, morbidity and residual functional disability. In recent years, there have been widespread indications for the correct management of VKA associated ICH. The urgent OAT reversal represents the cornerstone of VKA associated ICH therapy. The knowledge of these guidelines is of fundamental importance in clinical practice. The urgent OAT reversal could stop the hematoma enlargement which is considered one of the main risk factor of poor outcome in this clinical setting. The aim of urgent OAT reversal is bringing the INR (International Normalized Ratio) to values ≤ 1.4. It is possible by using prothrombin complex concentrate (PCC), fresh frozen plasma (FFP), recombinant activated factor VII (raFVII) together with vitamin K1 intravenous infusion. In this article the Authors review the practical management of urgent OAT reversal in patients suffering for VKA related ICH.


2012 ◽  
Vol 10 (1) ◽  
pp. 17 ◽  
Author(s):  
Rune Rasmussen ◽  
Pernille Corell ◽  
Poul Madsen ◽  
Karsten Overgaard

1977 ◽  
Vol 37 (02) ◽  
pp. 222-232 ◽  
Author(s):  
D. A Tibbutt ◽  
C. N Chesterman ◽  
E. W Williams ◽  
T Faulkner ◽  
A. A Sharp

SummaryTreatment with streptokinase (‘Kabikinase’) was given to 26 patients with venographically confirmed deep vein thrombosis extending into the popliteal vein or above. Treatment was continued for 4 days and the patients were allocated randomly to oral anticoagulant therapy or a course of treatment with ancrod (‘Arvin’) for 6 days followed by oral anticoagulant therapy. The degree of thrombolysis as judged by further venographic examination at 10 days was not significantly different between the 2 groups. The majority of patients showed clinical improvement but there was no appreciable difference between the groups at 3 and 6 months. Haemorrhagic complications were a more serious problem during the period of treatment with ancrod than during the equivalent period in the control group.


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