Effect of Day of the Week on Mortality and Cardiovascular Outcomes Following Elective AAA Repair and Lower Limb Revascularizations: A Population-Based Study

Background. The purpose of this study was to evaluate the overall survival (OS) and associated characteristics for patients with Myxoid Liposarcoma (MLS) over time in The Netherlands. Methods. A population-based study was performed of patients with primary localized (n = 851) and metastatic (n = 50) MLS diagnosed in The Netherlands between 1989 and 2016, based on data from the National Cancer Registry. Results. The median age of the MLS patients was 49 years, and approximately two-thirds was located in the lower limb. An association was revealed between age and the risk of having a Round Cell (RC) tumor. OS rates for primary localized MLS were 93%, 83%, 78%, and 66% after 1, 3, 5, and 10 years, respectively. The median OS for patients with metastatic disease at diagnosis was 10 months. Increasing age (Hazard Ratio (HR) 1.05, p=0.00), a tumor size >5 cm (HR 2.18; p=0.00), and tumor location (trunk HR 1.29; p=0.09, upper limb HR 0.83; p=0.55, and “other” locations HR 2.73; p=0.00, as compared to lower limb) were independent prognostic factors for OS. The percentage of patients treated with radiotherapy (RT) increased over time, and preoperative RT gradually replaced postoperative RT. In contrast to patients with localized disease, significant improvement of OS was observed in patients with metastatic disease over time. Conclusions. In this large nationwide cohort, tumor size and tumor location were independent prognostic factors for OS. Furthermore, a higher probability of an RC tumor with increasing age was suggested. An increased use of RT over the years did not translate into improved OS for localized MLS.

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PCV83 Adherence to Antihypertensive Agents After a Recent Ischemic Stroke and Risk of Cardiovascular Outcomes : A Population Based Study

Value in Health ◽

10.1016/j.jval.2012.08.1026 ◽

2012 ◽

Vol 15 (7) ◽

pp. A377

Author(s):

S. Perreault ◽

A.Y.X. Yu ◽

R. Côté ◽

A. Dragomir ◽

B. White-guay ◽

...

Keyword(s):

Ischemic Stroke ◽

Antihypertensive Agents ◽

Population Based ◽

Cardiovascular Outcomes ◽

Population Based Study

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Cardiovascular outcomes associated with use of clarithromycin: population based study

BMJ ◽

10.1136/bmj.h6926 ◽

2016 ◽

pp. h6926 ◽

Cited By ~ 62

Author(s):

Angel Y S Wong ◽

Adrian Root ◽

Ian J Douglas ◽

Celine S L Chui ◽

Esther W Chan ◽

...

Keyword(s):

Population Based ◽

Cardiovascular Outcomes ◽

Population Based Study

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Cardiovascular Outcomes of Obesity According to Menopausal Status: A Nationwide Population-Based Study

Endocrinology and Metabolism ◽

10.3803/enm.2021.1197 ◽

2021 ◽

Author(s):

Bo Kyung Koo ◽

Sang-Hyun Park ◽

Kyungdo Han ◽

Min Kyong Moon

Keyword(s):

Menopausal Status ◽

Population Based ◽

Cardiovascular Outcomes ◽

Population Based Study

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Abstract 16375: The Association Between Pregestational Hypertension and Cardiovascular Events in Pregnant Females, a Population-based Study

Circulation ◽

10.1161/circ.142.suppl_3.16375 ◽

2020 ◽

Vol 142 (Suppl_3) ◽

Author(s):

Mohamed M Gad ◽

Jasmin Abdeldayem ◽

Devora lichtman ◽

Islam Y Elgendy ◽

Anas M Saad ◽

...

Keyword(s):

Pregnant Women ◽

Multivariate Regression ◽

Nationwide Inpatient Sample ◽

Multivariate Regression Analysis ◽

Population Based ◽

Cardiovascular Outcomes ◽

P Value ◽

Population Based Study ◽

Pregnant Females ◽

The Impact

Introduction: Pregestational hypertension is associated with poor fetal and maternal outcomes, however, the impact on maternal cardiovascular outcomes is not well defined. In this study, we aim to study the impact of pregestational hypertension on maternal cardiovascular outcomes. Methods: Pregnant women hospitalized from January 2016 to December 2017 were identified in the Nationwide Inpatient Sample. Pregnant females with pregestational hypertension were identified using AHRQ comorbidity measures. Outcomes of interest were mortality, myocardial infarction (MI), and stroke. Multivariate regression analysis adjusting for differences in baseline comorbidities was used for odds ratio (OR) and 95% confidence interval (CI). Results: Among 8,141,277 pregnant women, 224,295 (2.76%) had pregestational hypertension. Pregnant females with pregestational hypertension were significantly older (mean age of 31.52 +/- 6.03 vs. 28.65 +/- 5.84, p-value<0.001), and had a higher burden of comorbidities includingpregestational diabetes mellitus (10.4% vs. 1.1%, p-value<0.001), gestational diabetes (26.3% vs. 8.1%, p-value<0.001), obesity (27.6% vs. 7.7%, p-value<0.001), smoking (16.4% vs. 9.8%,p-value<0.001), hyperlipidemia (2.1% vs. 0.2%, p-value<0.001), and depression; 6.6% vs. 3.0%, p-value<0.001. Females with pregestational hypertension had more cesarean section; 46.6% vs. 29.2%, p-value<0.001, intra-uterine death; 1.3% vs. 0.4%, p-value<0.001, and spontaneous abortion; 0.6% vs. 0.3%, p-value<0.001. Pregetational hypertension had higher mortality rate (55.7 vs. 10.1 per 100,000 hospitalizations, p-value<0.001), MI rate (207.3 vs. 9.3 per 100,000 hospitalizations, p-value<0.001), and stroke rate (288.4 vs. 22.6 per 100,000 hospitalizations, p-value<0.001). Pregestational hypertension was associated with significantly worse outcomes including in-hospital mortality (aOR 3.01, 95% CI 2.48-3.67), MI (aOR 8.27, 95% CI 7.30-9.35), and stroke (aOR 9.31, 95% CI 8.47-10.24). Conclusions: Pregestational hypertension is associated with poor maternal cardiovascular outcomes in pregnancy. Further efforts should be directed to identifying high-risk females and better approaches to management are warranted.

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