The influence of cholinergic agents on histamine release from HMC-1 human mast cell line stimulated with IgG, C-reactive protein and compound 48/80

Life Sciences ◽  
2012 ◽  
Vol 91 (21-22) ◽  
pp. 1053-1057 ◽  
Author(s):  
Peter G. Nazarov ◽  
Anastasia P. Pronina
Keyword(s):  
Mast Cell ◽  
Histamine Release ◽  
Cell Line ◽  
Human Mast Cell ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Cholinergic Agents ◽  
Mast Cell Line

scholarly journals Cysteine Protease Activity and Histamine Release from the Human Mast Cell Line HMC-1 Stimulated by Recombinant Streptococcal Pyrogenic Exotoxin B/Streptococcal Cysteine Protease

2002 ◽  
Vol 70 (7) ◽  
pp. 3944-3947 ◽  
Author(s):  
Yukino Watanabe ◽  
Yuko Todome ◽  
Hisashi Ohkuni ◽  
Shinsaku Sakurada ◽  
Toshio Ishikawa ◽  
...  
Keyword(s):  
Mast Cell ◽  
Histamine Release ◽  
Cell Line ◽  
Cysteine Protease ◽  
Protease Activity ◽  
Human Mast Cell ◽  
Streptococcal Toxic Shock Syndrome ◽  
Streptococcal Pyrogenic Exotoxin B ◽  
Mast Cell Line ◽  
Spe B

ABSTRACT We constructed the expression vector pSK-SCP containing the streptococcal exotoxin B gene (spe b) which expressed protease activity. We showed that the recombinant streptococcal pyogenic exotoxin B/streptococcal cysteine protease (rSPE B/SCP) was secreted into the culture supernatant of the transformant and retained its SCP activity, which was equivalent to or greater than that of the naturally occurring molecule. The secreted rSPE B/SCP induced histamine release and degranulation of the human mast cell line HMC-1. This study may contribute to the understanding of the pathogenic role of SPE B/SCP in streptococcal infection and streptococcal toxic shock syndrome.

scholarly journals Transcriptional complexity of the HSPG2 gene in the human mast cell line, HMC-1

2014 ◽  
Vol 35 ◽  
pp. 123-131 ◽  
Author(s):  
Megan S. Lord ◽  
MoonSun Jung ◽  
Bill Cheng ◽  
John M. Whitelock
Keyword(s):  
Mast Cell ◽  
Cell Line ◽  
Human Mast Cell ◽  
Mast Cell Line

Cytokine release from a human mast cell line (HMC-1) in response to stimulation with anti-IgE and other secretagogues

2000 ◽  
Vol 49 (S1) ◽  
pp. 7-8 ◽  
Author(s):  
J. Wierecky ◽  
J. Grabbe ◽  
H. H. Wolff ◽  
B. F. Gibbs
Keyword(s):  
Mast Cell ◽  
Cell Line ◽  
Human Mast Cell ◽  
Cytokine Release ◽  
Mast Cell Line

The Human Mast Cell Line HMC‐1 Expresses C5a Receptors and Responds to C5a but not to C5a(desArg)

1996 ◽  
Vol 44 (1) ◽  
pp. 30-36 ◽  
Author(s):  
T. WERFEL ◽  
M. OPPERMANN ◽  
J. H. BUTTERFIELD ◽  
G. BEGEMANN ◽  
J. ELSNER ◽  
...  
Keyword(s):  
Mast Cell ◽  
Cell Line ◽  
Human Mast Cell ◽  
C5a Receptors ◽  
Mast Cell Line

Quercetin inhibits expression of inflammatory cytokines through attenuation of NF-κB and p38 MAPK in HMC-1 human mast cell line

2007 ◽  
Vol 56 (5) ◽  
pp. 210-215 ◽  
Author(s):  
Y.-D. Min ◽  
C.-H. Choi ◽  
H. Bark ◽  
H.-Y. Son ◽  
H.-H. Park ◽  
...  
Keyword(s):  
Mast Cell ◽  
Cell Line ◽  
P38 Mapk ◽  
Inflammatory Cytokines ◽  
Human Mast Cell ◽  
Mast Cell Line
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