CC chemokine receptor 2 functions in osteoblastic transformation of valvular interstitial cells

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Zihao Liu ◽  
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Bingqing Deng ◽  
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Author(s):  
Bedia Agachan ◽  
Rukset Attar ◽  
Elif Isbilen ◽  
Hulya Yilmaz Aydogan ◽  
Seyma Sozen ◽  
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Vol 13 (1) ◽  
pp. 156-159 ◽  
Author(s):  
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Rosemarijn Renckens ◽  
Alex F. de Vos ◽  
Dagmar Kunz ◽  
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ABSTRACT Upon injection of Escherichia coli lipopolysaccharide into human volunteers, the monocyte density of CC chemokine receptor 2 (CCR2) decreased. Minimal CCR2 density was observed 4 h after injection. Peak plasma concentrations of the CCR2 ligand monocyte chemotactic protein 1 and of tumor necrosis factor alpha were reached after 4 h and 2 h, respectively.


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