Recent insights in pituitary diseases.

2021 ◽  
pp. 104094
Author(s):  
Philippe Chanson
Keyword(s):  
Pituitary Diseases

Use of tolvaptan in acute post-surgical hyponatremia in patients with pituitary diseases

2020 ◽  
Author(s):  
Emanuele Ferrante ◽  
Rita Indirli ◽  
Beatrice Mantovani ◽  
Arianna Cremaschi ◽  
Serban Andreea Liliana ◽  
...  
Keyword(s):  
Pituitary Diseases

scholarly journals Reappraising the Role of Trans-Sphenoidal Surgery in Prolactin-Secreting Pituitary Tumors

Cancers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 3252
Author(s):  
Pier Paolo Mattogno ◽  
Quintino Giorgio D’Alessandris ◽  
Sabrina Chiloiro ◽  
Antonio Bianchi ◽  
Antonella Giampietro ◽  
...  
Keyword(s):  
Pituitary Tumors ◽  
Female Gender ◽  
Clinical History ◽  
Serum Prolactin ◽  
Cure Rate ◽  
Cross Sectional ◽  
Unique Challenge ◽  
Best Management ◽  
Pituitary Diseases

Background: Prolactinomas represent a unique challenge for endocrinologists and neurosurgeons. Considering recent innovations in surgical practice, the authors aimed to investigate the best management for prolactinomas. Methods: A retrospective, cross-sectional and monocentric study was designed. Consecutive patients affected by prolactinomas were enrolled if treated with a first-line treatment with a dopamine agonist (DA) or trans-sphenoidal surgery (TSS). Patients carried giant prolactinomas, and those with a follow-up <12 months were excluded. Results: Two hundred and fifty-nine patients were enrolled. The first treatment was DA for 140 patients and TS for 119 cases. One hundred and forty-six of 249 patients (58.6%) needed a second therapy. The mean follow-up was 102.2 months (12–438 months). Surgery highly impacted on the cure rate—in particular, in females (p = 0.0021) and in microprolactinomas (p = 0.0020). Considering the multivariate analysis, the female gender and surgical treatment in the course of the clinical history were the only independent positive predictors of a cure at the end of 5 years follow-up (p = 0.0016, p = 0.0005). The evaluation of serum prolactin (24 hours after TSS) revealed that 86.4% of patients with postoperative prolactin (PRL) ≤10 ng/mL were cured at the end of the follow-up (p < 0.0001). Conclusions: According to our experience, surgery allows a high cure rate of prolactinomas, particularly in females with microadenoma, with a good safety profile. TSS for prolactinomas should be considered as a concrete option, during the multidisciplinary evaluation, in centers of reference for pituitary diseases.

Usefulness of plasma pregnenolone sulfate in testing pituitary-adrenal function in children

1986 ◽  
Vol 113 (4_Suppl) ◽  
pp. S259-S263 ◽  
Author(s):  
E. de Peretti ◽  
M.G. Forest ◽  
B. Loras ◽  
Y. Morel ◽  
M. David ◽  
...  
Keyword(s):  
Normal Subjects ◽  
Adrenal Function ◽  
Pituitary Function ◽  
First Year ◽  
Dynamic Tests ◽  
Pregnenolone Sulfate ◽  
Pituitary Diseases ◽  
First Year Of Life ◽  
Dexamethasone Suppression ◽  
Abrupt Rise

SUMMARY In normal subjects, plasma pregnenolone sulfate (PS) levels high at birth, decreased during the first year of life in relation to the pattern of involution of the fetal adrenal zone. Thereafter, PS levels, in contrast with those of DHAS, did not show the abrupt rise characteristic of the adrenarche, but increased very progressively till adulthood. The response of PS to various provocative tests of adrenal and pituitary function (ACTH and Metyrapone stimulation, dexamethasone suppression), has been established in normal subjects. The measurement of plasma PS levels in basal conditions as well as in response to dynamic tests was very useful in the diagnosis of various adrenal and pituitary diseases in children.

scholarly journals Plasma LH, FSH and TSH responses to the synthetic enkephalin analog (FK 33-824) in normal subjects and patients with pituitary diseases.

1982 ◽  
Vol 137 (3) ◽  
pp. 283-287 ◽  
Author(s):  
REIKO DEMURA ◽  
TOSHIHIRO SUDA ◽  
ICHIJI WAKABAYASHI ◽  
MASAMI ONO ◽  
KAZUKO JIBIKI ◽  
...  
Keyword(s):  
Normal Subjects ◽  
Pituitary Diseases

scholarly journals Pituitary Diseases and Bone

2018 ◽  
Vol 39 (4) ◽  
pp. 440-488 ◽  
Author(s):  
Gherardo Mazziotti ◽  
Stefano Frara ◽  
Andrea Giustina
Keyword(s):  
Pituitary Diseases

Miscellaneous Pituitary Diseases

2015 ◽  
pp. 177-177
Author(s):  
Suvarna Khadilkar ◽  
Vibha More
Keyword(s):  
Pituitary Diseases

Endocrine disorders in pregnancy

2018 ◽  
pp. 283-296
Author(s):  
Helen E. Turner ◽  
Richard Eastell ◽  
Ashley Grossman
Keyword(s):  
Thyroid Hormone ◽  
Hyperemesis Gravidarum ◽  
Post Partum ◽  
Management Strategies ◽  
Normal Pregnancy ◽  
Endocrine Disorders ◽  
Pituitary Diseases ◽  
Pregnant State ◽  
Pituitary Adrenal Axis ◽  
In Pregnancy

This chapter discusses thyroid, adrenal, and pituitary diseases that occur during pregnancy. A series of changes in thyroid hormone economy take place in normal pregnancy. As a result of these changes, thyroid hormone levels in pregnancy differ from those in the non-pregnant state. This chapter includes a description of normal thyroid physiology and thyroid pathophysiology, including hyperemesis gravidarum, post-partum thyroiditis, hypothyroidism, and hyperthyroidism. Changes in the hypothalamo-pituitary–adrenal axis during normal and abnormal pregnancies are also described, with syndromes such as Cushing’s syndrome and Addison’s disease listed. Finally, pituitary adenomas in pregnancy, and their respective features and management strategies, are listed, including acromegaly, hypopituitarism, TSH-secreting adenomas, and prolactinoma.

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