The potential effect of Wuqinxi exercise for primary osteoporosis: A systematic review and meta-analysis

Maturitas ◽  
2015 ◽  
Vol 82 (4) ◽  
pp. 346-354 ◽  
Author(s):  
Xu Wei ◽  
Aili Xu ◽  
Yukun Yin ◽  
Ranxing Zhang
Bone ◽  
2020 ◽  
Vol 130 ◽  
pp. 115121 ◽  
Author(s):  
Fang Lv ◽  
Xiaoling Cai ◽  
Wenjia Yang ◽  
Leili Gao ◽  
Ling Chen ◽  
...  

BMJ Open ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. e032315 ◽  
Author(s):  
Amy Drahota ◽  
Lambert M Felix ◽  
Bethany E Keenan ◽  
Chantelle C Lachance ◽  
Andrew Laing ◽  
...  

IntroductionFalls in hospitals and care homes are a major issue of international concern. Inpatient falls are the most commonly reported safety incident in the UK’s National Health Service (NHS), costing the NHS £630 million a year. Injurious falls are particularly life-limiting and costly. There is a growing body of evidence on shock-absorbing flooring for fall-related injury prevention; however, no systematic review exists to inform practice.Methods and analysisWe will systematically identify, appraise and summarise studies investigating the clinical and cost-effectiveness, and experiences of shock-absorbing flooring in hospitals and care homes. Our search will build on an extensive search conducted by a scoping review (inception to May 2016). We will search electronic databases (AgeLine, CINAHL, MEDLINE, NHS Economic Evaluation Database, Scopus and Web of Science; May 2016–present), trial registries and grey literature. We will conduct backward and forward citation searches of included studies, and liaise with study researchers. We will evaluate the influence of floors on fall-related injuries, falls and staff work-related injuries through randomised and non-randomised studies, consider economic and qualitative evidence, and implementation factors. We will consider risk of bias, assess heterogeneity and explore potential effect modifiers via subgroup analyses and sensitivity analyses. Where appropriate we will combine studies through meta-analysis. We will use the GRADE (Grading of Recommendations, Assessment, Development and Evaluations) approach to evaluate the quality of evidence and present the results using summary of findings tables, and adhere to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting guidelines.Ethics and disseminationWe will follow the ethical principles of systematic review conduct, by attending to publication ethics, transparency and rigour. Our dissemination plan includes peer-reviewed publication, presentations, press release, stakeholder symposium, patient video and targeted knowledge-to-action reports. This review will inform decision-making around falls management in care settings and identify important directions for future research.PROSPERO registration numberCRD42019118834.


2020 ◽  
Vol 11 (5) ◽  
pp. 3781-3799
Author(s):  
Shoumeng Yan ◽  
Changcong Wang ◽  
Hantong Zhao ◽  
Yingan Pan ◽  
Han Wang ◽  
...  

Previous studies have shown that fasting produces a potential effect in the prevention and treatment of many diseases.


2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Peter Schwarz ◽  
Niklas Rye Jorgensen ◽  
Leif Mosekilde ◽  
Peter Vestergaard

Purpose. Fragility fractures in men constitute a major worldwide public health problem with a life-time risk of 13%. It cannot be directly inferred that antiosteoporotic drugs effective in women have the same effect in men. Our aim was to appraise the existing evidence for efficacy of osteoporosis treatment in men.Methods. This study was a systematic review of the published literature on the clinical efficacy of medical osteoporosis therapy in the reduction of fracture risk in men (age>50 years). Studies included were randomised, placebo-controlled trials of men.Results. Five BMD studies of antiresorptive treatment were included. All studies showed an increase in BMD, but there was only a nonsignificant trend in the reduction of clinical fractures. Three BMD studies of anabolic treatment with teriparatide were also included. These showed a significant mean increase in spine BMD and for vertebral fractures a non-significant trend towards a reduction was seen.Conclusion. The evidence of medical osteoporosis treatment in men is scant and inconclusive due to the lack of prospective RCT studies with fracture prevention as primary end point. So far, all evidence is based on BMD increases in small RCT studies showing BMD increases comparable to those reported in postmenopausal women.


2021 ◽  
Author(s):  
Siyi Zhu ◽  
Yi Li ◽  
Liqiong Wang ◽  
Jinming Huang ◽  
Kangping Song ◽  
...  

Question(s): What is the effectiveness of pulsed electromagnetic fields (PEMFs) for the management of primary osteoporosis in older adults? Design: Systematic review and meta-analysis of randomised or quasi-randomised controlled trial. Participants: Older adults aged over 50 years with primary osteoporosis. Intervention: PEMFs at extremely low frequencies. Outcome measures: Bone mass, number of incident fractures, functional assessments, and adverse events. Results: Eight trials including 396 participants met the inclusion criteria. Low certainty evidence showed that PEMFs was non-inferior to conventional pharmacological agents in preventing the decline of Bone Mineral Density (BMD) at the lumbar (MD 0.01; CI -0.04 to 0.06) and femur neck (MD 0.01; CI -0.02 to 0.04), and improving balance function measured by Berg Balance Scale (BBS) (MD 0.01; CI -0.09 to 0.11) and Timed Up and Go test (MD -0.04; CI -0.80 to 0.72), directly after intervention. The similar effects were observed in BMD and BBS at 12- and 24-weeks follow-up from baseline with moderate certainty evidence. Very low certainty evidence showed that PEMFs (versus exercise) had small but significant effect on BMD at the femur neck (MD 0.10; CI 0.01 to 0.20), and no effect on BMD at the lumbar (MD 0.15; CI -0.04 to 0.35). Conclusion: PEMFs had positive effects non-inferior to first-line treatment on BMD and balance function in older adults with primary osteoporosis, but with low to very low certainty evidence and short-term follow-ups. There is a need for high-quality randomised controlled trials evaluating PEMFs for the management of primary osteoporosis. Registration: PROSPERO CRD42018099518.


2020 ◽  
Author(s):  
Weiwei Huang ◽  
Jiao Li ◽  
Wenxiong Li ◽  
Mingquan Yuan ◽  
Rongqaing Zhang ◽  
...  

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