Racial Disparities in Inhospital Outcomes for Hepatocellular Carcinoma in the United States

2016 ◽  
Vol 91 (9) ◽  
pp. 1173-1182 ◽  
Author(s):  
Ruma Rajbhandari ◽  
Rachel E. Simon ◽  
Raymond T. Chung ◽  
Ashwin N. Ananthakrishnan
2018 ◽  
Vol 36 (4_suppl) ◽  
pp. 249-249
Author(s):  
Michael Ross Kaufman ◽  
David J. Delgado ◽  
Stephanie Costa ◽  
Brandon George ◽  
Edith P. Mitchell

249 Background: Insufficient evidence exists regarding the presentation and management of elderly patients with hepatocellular carcinoma (HCC). The purpose of this study was to describe racial differences in cancer staging of elderly (65+) patients with HCC diagnosed in the United States. Methods: A retrospective cohort study was conducted using the 1973-2014 Surveillance, Epidemiology and End Results Program (SEER) database of the National Cancer Institute. Patients with primary hepatocellular carcinoma, diagnosed between 2004 and 2014, and with complete information on race, gender, year of diagnosis, age, marital status, region and stage at diagnosis (Derived SEER Summary Stage 2000, and Derived American Joint Committee on Cancer (AJCC) Stage Group, 6th Edition) were included. Descriptive statistics were used to compare sociodemographic and clinical variables with race. Univariate and multivariate logistic regressions were preformed to describe the association of race with the diagnosis of late stage HCC (Regional/Distant vs Localized Stage for SEER Summary Stage, and Stage III/IV vs Stage I/II for AJCC Stage Group). Results: The sample consisted of 19,902 HCC patients: 69.7% White, 9.2% Black, 20.2% API, 1.0% AI; 69.1% male; 45.1% diagnosed in 2004-2009; 56.2% age 65-74, 35.6% 75-84, and 8.2% 85 and older; 58.3% married; 7.4% Midwest, 12.4% Northeast, 17.0% Southeast, 63.2% Pacific West; 44.9% Regional/Distant Stage (SEER Summary Stage) and 41.2% Stage III/IV (AJCC Stage Group). After controlling for confounding variables, Asian/Pacific Islanders had a decreased odds of presenting with late stage disease relative to whites in both the SEER Summary Stage (OR: 0.867, CI:0.805-0.934) and AJCC Stage Group (OR: 0.904, CI:0.838-0.975). Conclusions: Racial disparities exist at the presentation of HCC in the 65+ population. Asian/Pacific Islanders are less likely to be diagnosed with late stage HCC compared to whites. There is a need to study further these relationships in subpopulations.


2018 ◽  
Vol 36 (4_suppl) ◽  
pp. 431-431
Author(s):  
Stephanie Costa ◽  
David J. Delgado ◽  
Michael Ross Kaufman ◽  
Brandon George ◽  
Edith P. Mitchell

431 Background: Insufficient evidence exists regarding the initial management of elderly patients with hepatocellular carcinoma (HCC). The purpose of this study was to describe racial differences in initial treatment of 65+ year old patients with HCC diagnosed in the United States (2004-2014). Methods: A retrospective cohort study was conducted using the 1973-2014 Surveillance, Epidemiology and End Results Program (SEER) database of the National Cancer Institute. Patients with primary hepatocellular carcinoma, diagnosed between 2004 and 2014, and with complete information on race, gender, year of diagnosis, age, marital status, region, tumor status at diagnosis and initial treatment were included. Descriptive statistics were used to compare race with sociodemographic and clinical variables. Univariate and multivariate logistic regressions were performed to describe the association of race with receiving any treatment for HCC (local hepatic therapy and surgical treatment versus no treatment). Results: The sample consisted of 25,499 HCC patients: 70.0% White, 9.1% Black, 19.8% API, 1.0% AI; 68.6% male; 46.8% diagnosed in 2004-2009; 54.8% age 65-74, 45.2% 75 and older; 54.7% married, 7.3% Midwest, 13.8% Northeast, 15.7% Southeast; 81.3% first malignant primary indicator, 13.8% metastasis, 49.3% localized site, and 20.9% receiving initial treatment. After controlling for confounding variables, as compared to White patients, African American patients (OR:0.739 95% CI:0.652, 0.839) had decreased odds of receiving initial treatment; and Asian/Pacific Islander patients (OR:1.490 95% CI:1.371,1.618) had increased odds of receiving initial treatment. Conclusions: Racial disparities exist at the presentation of HCC in the 65+ population. African American patients are less likely to receive treatment and Asian/Pacific Islander patients are more likely to receive treatment. Further research is needed to understand these relationships in subpopulations.


2008 ◽  
Vol 103 (1) ◽  
pp. 120-127 ◽  
Author(s):  
Abby B Siegel ◽  
Russell B McBride ◽  
Hashem B El-Serag ◽  
Dawn L Hershman ◽  
Robert S Brown ◽  
...  

2015 ◽  
Vol 148 (4) ◽  
pp. S-1069-S-1070
Author(s):  
Ruma Rajbhandari ◽  
Raymond T. Chung ◽  
Ashwin N. Ananthakrishnan

2021 ◽  
pp. 014616722110241
Author(s):  
Shai Davidai ◽  
Jesse Walker

What do people know about racial disparities in “The American Dream”? Across six studies ( N = 1,761), we find that American participants consistently underestimate the Black–White disparity in economic mobility, believing that poor Black Americans are significantly more likely to move up the economic ladder than they actually are. We find that misperceptions about economic mobility are common among both White and Black respondents, and that this undue optimism about the prospect of mobility for Black Americans results from a narrow focus on the progress toward equality that has already been made. Consequently, making economic racial disparities salient, or merely reflecting on the unique hardships that Black Americans face in the United States, calibrates beliefs about economic mobility. We discuss the importance of these findings for understanding lay beliefs about the socioeconomic system, the denial of systemic racism in society, and support for policies aimed at reducing racial economic disparities.


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