Cytoprotective effect of kaempferol against palmitic acid-induced pancreatic β-cell death through modulation of autophagy via AMPK/mTOR signaling pathway

Molecular and Cellular Endocrinology ◽

10.1016/j.mce.2017.02.033 ◽

2017 ◽

Vol 448 ◽

pp. 1-20 ◽

Author(s):

Ritu Varshney ◽

Sumeet Gupta ◽

Partha Roy

Keyword(s):

Palmitic Acid ◽

Signaling Pathway ◽

Mtor Signaling ◽

Pancreatic Β Cell ◽

Mtor Signaling Pathway ◽

Cytoprotective Effect ◽

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Diosgenin reduces phosphodiesterase 3B (PDE3B) through AMP-activated protein kinase/ mechanistic target of rapamycin (AMPK/mTOR) signaling pathway to ameliorate streptozotocin-induced pancreatic β-cell apoptosis and dysfunction

Bioengineered ◽

10.1080/21655979.2021.2023996 ◽

2022 ◽

Vol 13 (2) ◽

pp. 2217-2225

Author(s):

Lijie Ma ◽

Chengfei Zhang ◽

Lili Wu ◽

Lingling Qin ◽

Tonghua Liu

Keyword(s):

Protein Kinase ◽

Signaling Pathway ◽

Cell Apoptosis ◽

Mtor Signaling ◽

Pancreatic Β Cell ◽

Mtor Signaling Pathway ◽

Β Cell ◽

Mechanistic Target Of Rapamycin ◽

Phosphodiesterase 3B ◽

Amp Activated Protein Kinase

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Abstract A18: Geranylgeranoic acid (GGA) induced autophagic cell death through induction of unfolded protein response (UPR) and suppression of mTOR signaling pathway

10.1158/1538-8514.pi3k14-a18 ◽

2015 ◽

Author(s):

Chieko Iwao ◽

Yoshihiro Shidoji

Keyword(s):

Unfolded Protein Response ◽

Signaling Pathway ◽

Mtor Signaling ◽

Autophagic Cell Death ◽

Mtor Signaling Pathway ◽

Unfolded Protein ◽

Protein Response

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Cadmium exposure induces pancreatic β-cell death via a Ca2+-triggered JNK/CHOP-related apoptotic signaling pathway

10.1016/j.tox.2019.152252 ◽

2019 ◽

Vol 425 ◽

pp. 152252 ◽

Author(s):

Cheng-Chin Huang ◽

Chun-Ying Kuo ◽

Ching-Yao Yang ◽

Jui-Ming Liu ◽

Ren-Jun Hsu ◽

...

Keyword(s):

Signaling Pathway ◽

Cadmium Exposure ◽

Pancreatic Β Cell ◽

Β Cell ◽

Apoptotic Signaling

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PAMAM Nanoparticles Promote Acute Lung Injury by Inducing Autophagic Cell Death through the Akt-TSC2-mTOR Signaling Pathway

Journal of Molecular Cell Biology ◽

10.1093/jmcb/mjp002 ◽

2009 ◽

Vol 1 (1) ◽

pp. 37-45 ◽

Author(s):

C. Li ◽

H. Liu ◽

Y. Sun ◽

H. Wang ◽

F. Guo ◽

...

Keyword(s):

Acute Lung Injury ◽

Lung Injury ◽

Signaling Pathway ◽

Mtor Signaling ◽

Autophagic Cell Death ◽

Mtor Signaling Pathway

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PAMAM Nanoparticles Promote Acute Lung Injury by Inducing Autophagic Cell Death through the Akt-TSC2-mTOR Signaling Pathway

Journal of Molecular Cell Biology ◽

10.1093/jmcb/mjq003 ◽

2010 ◽

Vol 2 (2) ◽

pp. 103-103 ◽

Author(s):

C. Li ◽

H. Liu ◽

Y. Sun ◽

H. Wang ◽

F. Guo ◽

...

Keyword(s):

Acute Lung Injury ◽

Lung Injury ◽

Signaling Pathway ◽

Mtor Signaling ◽

Autophagic Cell Death ◽

Mtor Signaling Pathway

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Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway

Scientific Reports ◽

10.1038/s41598-017-10407-w ◽

2017 ◽

Vol 7 (1) ◽

Author(s):

Yujun Xu ◽

Yizhong Wang ◽

Anran Yao ◽

Zhen Xu ◽

Huan Dou ◽

...

Keyword(s):

Lung Cancer ◽

Magnetic Fields ◽

Signaling Pathway ◽

Low Frequency ◽

Mtor Signaling ◽

Mtor Signaling Pathway

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Retraction: PM02734 (Elisidepsin) Induces Caspase-Independent Cell Death Associated with Features of Autophagy, Inhibition of the Akt/mTOR Signaling Pathway, and Activation of Death-Associated Protein Kinase

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-13-1910 ◽

2013 ◽

Vol 19 (17) ◽

pp. 4900-4900

Keyword(s):

Protein Kinase ◽

Signaling Pathway ◽

Mtor Signaling ◽

Mtor Signaling Pathway ◽

Death Associated Protein Kinase ◽

Autophagy Inhibition

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Suppression of PI3K-Akt-mTOR Signaling Pathway in Paradoxical EGF-Induced Cell Death

Annals of Oncology ◽

10.1093/annonc/mdt459.129 ◽

2013 ◽

Vol 24 ◽

pp. ix59

Author(s):

W. Hong-Gyun ◽

K. Kim ◽

S.-R. Jeon

Keyword(s):

Signaling Pathway ◽

Mtor Signaling ◽

Mtor Signaling Pathway

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Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy

Autophagy ◽

10.4161/auto.9099 ◽

2009 ◽

Vol 5 (6) ◽

pp. 824-834 ◽

Author(s):

You-Tong Wu ◽

Hui-Ling Tan ◽

Qing Huang ◽

Choon-Nam Ong ◽

Han-Ming Shen

Keyword(s):

Signaling Pathway ◽

Mtor Signaling ◽

Necrotic Cell Death ◽

Mtor Signaling Pathway ◽

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Coptisine induces autophagic cell death through down-regulation of PI3K/Akt/mTOR signaling pathway and up-regulation of ROS-mediated mitochondrial dysfunction in hepatocellular carcinoma Hep3B cells

Archives of Biochemistry and Biophysics ◽

10.1016/j.abb.2020.108688 ◽

2021 ◽

Vol 697 ◽

pp. 108688

Author(s):

So Young Kim ◽

Hyun Hwangbo ◽

Min Yeong Kim ◽

Seon Yeong Ji ◽

Hyesook Lee ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Mitochondrial Dysfunction ◽

Signaling Pathway ◽

Mtor Signaling ◽

Autophagic Cell Death ◽

Mtor Signaling Pathway ◽

Down Regulation ◽

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